LIFE TECHNOLOGIES INC -- 15596-026 TRIZOL REAGENT
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Material Safety Data Sheet
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MSDS Num: BZDPQ
MSDS NAME: 15596-026 TRIZOL REAGENT
Responsible Party
Name: LIFE TECHNOLOGIES INC
Address: 8451 HELGERMAN CT
Box: 6009
City: GAITHERSBURG MD 20884
Info Phone: 301-431-8585
Emergency Phone Number: 301-431-8585
Review Ind: Y
Published: Y
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Preparer Co. when other than Responsible Party Co.
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Name: LIFE TECHNOLOGIES INC
Address: 8451 HELGERMAN CT
Box: 6009
City: GAITHERSBURG MD 20884
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Contractor Summary
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Name: LIFE TECHNOLOGIES INC
Address: 8451 HELGERMAN CT
Box: 6009
City: GAITHERSBURG MD 20884
Phone: 301-431-8585
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Ingredients
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Cas: 108-95-2
RTECS #: SJ3325000
Name: PHENOL (IARC CARC - GROUP 3) *96-1*
% Wt: <50
Other REC Limits: 5 MG/CUM
OSHA PEL: 19 MG/CUM
ACGIH TLV: 19 MG/CUM (SKIN)
EPA Rpt Qty: 1000 LBS
DOT Rpt Qty: 1000 LBS
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Name: TRADE SECRET COMPONENT
% Wt: >50
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Health Hazards Data
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LD50 LC50 Mixture: ORAL LD50(RAT): 317 MG/KG
Route Of Entry Inds - Inhalation: YES
Skin: YES
Ingestion: YES
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: DEATH HAS BEEN REPORTED TO OCCUR W/IN 10 MINS AFTER SKIN
CONTACT. MAY BE FATAL IF ABSORBED THROUGH THE SKIN, INHALED/SWALLOWED. CAUSES
SEVERE BURNS TO SKIN, EYES, NOSE, THROAT, LUNGS/STOMACH. AREAS MA Y BECOME
DEEPLY ERODED & SCARRED. MAY DAMAGE CNS, KIDNEYS, LIVER, PANCREAS. (SEE
SUPP)
Explanation Of Carcinogenicity: NONE
Signs And Symptions Of Overexposure: CHEMICAL BURN, WATER/BLURRING OF THE EYES,
CONGESTION OF THE LUNGS/LIVER/KIDNEY/SPLEEN. IRRITATION, SWEATING, HEADACHE,
THIRST, NAUSEA, ABDOMINAL PAIN, DIARRHEA, CYANOSIS, TWITCHING, TREMORS,
CONVULSI ONS, COMA
Medical Cond Aggravated By Exposure: CONVULSIVE DISORDERS & ABNORMALITITES
OF THE SKIN, RESPIRATORY TRACT, KIDNEYS, LIVER & SPLEEN.
First Aid: THERE IS NO KNOWN ANTIDOTE. TREAT SYMPTOMATICALLY. INHALATION:
REMOVE TO FRESH AIR. GIVE CPR IF BREATHING HAS STOPPED. EYES/SKIN:
IMMEDIATELY FLUSH THOROUGHLY W/LARGE AMOUNTS OF WATER FOR 15 MINS. ING
ESTION: DON'T INDUCE VOMITING. GIVE EGGS, MILK/LARGE AMOUNTS OF WATER. OBTAIN
MEDICAL ATTENTION IN ALL CASES.
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Handling and Disposal
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Spill Release Procedures: EVACUATE AREA. WEAR PROTECTIVE EQUIPMENT. LAND:
CONTAIN W/DAMS/PITS. USE PROTECTIVE COVER; PLASTIC SHEET TO PREVENT
DISSOLVING IN FIRE FIGHTING WATER/RAIN. NEUTRALIZE. WATER: APPLY ACTIVATED
CHARCOAL AT RATE OF 10X THE MAOUNT OF MATERIAL. (SEE SUPP)
Neutralizing Agent: LAND-SLAKED LIME/CRUSHED LIMESTONE/SODIUM BICARBONATE.
Waste Disposal Methods: PHENOL MUST NOT BE DISCHARGED/RELEASED INTO
STREAMS/LAKES. RECOMMENDED DISPOSAL METHOD IS INCINERATION. DISPOSE OF
IAW/LOCAL, STATE & FEDERAL REGULATIONS. POISON UN2821. EPA WASTE NO: U188
(PHENOL).
Handling And Storage Precautions: STORAGE PRESSURE: ATMOSPHERIC. STORE <77F.
STORE IN A COOL, DRY, WELL VENTILATED PLACE AWAY FROM HEAT & OXIDIZERS.
KEEP CONTAINER TIGHTLY CLOSED.
Other Precautions: PROTECT FROM DAMAGE. DON'T GET ON SKIN, IN EYES/ON CLOTHING
& INHALE VAPORS. PHENOL IS SLIGHTLY TOXIC TO FISH & AQUATIC
INVERTEBRATES.
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Fire and Explosion Hazard Information
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Flash Point Method: CC
Flash Point Text: 167F
Extinguishing Media: CO2, DRY CHEMICAL, FOAM, WATER SPRAY
Fire Fighting Procedures: WEAR SELF CONTAINED BREATHING APPARATUS &
PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard: TOXIC/CAUSTIC VAPORS GENERATE WHEN PHENOL IS
HEATED. CAN REACT VIOLENTLY W/ALUMINUM CHLORIDE/NITROBENZENE, BUTADIENE &
OXIDIZERS TO FORM MIXTURES W/AIR.
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Control Measures
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Respiratory Protection: USE NIOSH-APPROVED W/ORGANIC VAPOR CARTRIDGE & MIST
FILTER (FOR HANDLING LARGER QUANTITIES/WHERE PHENOL VAPOR CONCENTRATIONS ARE
<125 PPM). USE SCBA W/FULL-FACE PROTECTION (WHERE A RELEASE OF PHENOL V
APOR CONCENTRATION IS >125 PPM).
Ventilation: LOCAL EXHAUST SYSTEM
Protective Gloves: NEOPRENE/EQUIVALENT
Eye Protection: SAFETY GLASSES W/SIDE SHIELDS
Other Protective Equipment: LAB COAT/IMPERVIOUS PROTECTIVE CLOTHING
(RUBBERIZED) FOR HANDLING LARGE QUANTITIES/MANAGING A SIGNIFICANT RELEASE.
Supplemental Safety and Health: SPILL PROC CONT'D: RELEASE TO ATMOSPHERE: APPLY
WATER SPRAY TO KNOCK DOWN & REDUCE VAPORS. KNOCK-DOWN WATER IS CONSIDERED
CORROSIVE & TOXIC. DIKE/DAM THE AREA TO CONTAIN THE KNOCK-DOWN WATER FOR
DISPO SAL. INCOMPATIBILITIES CONT'D: BORON TRIFLUORIDE, DIETHYLLEHERTE,
ALUMINUM, LEAD, MAGNESIUM, ZINC & THEIR ALLOYS.
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Physical/Chemical Properties
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B.P. Text: 359.24F
M.P/F.P Text: 105.5F
Vapor Pres: 0.35
Vapor Density: 3.24
Spec Gravity: 1.058
PH: 4-5
Solubility in Water: >100 MG/ML
Appearance and Odor: RED SOLUTION W/A SWEET, TARRY, PUNGENT AROMATIC ODOR
Percent Volatiles by Volume: 100
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: TEMPERATURES IN EXCESS OF 98.6F (NATURAL
DISCOLORS).
Materials To Avoid: ALUMINUM CHLORIDE, NITROBENZENE, BUTADIENE, OXIDIZERS,
ACIDS, CALCIUM HYPOCHLORITE, FORMALDEHYDE, ACETALDHYDE, (SEE SUPP
Hazardous Decomposition Products: BY THERMAL DECOMPOSITION: OXIDES OF CARBON,
NITROGEN, SULFUR, CO
Hazardous Polymerization Indicator: NO
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Toxicological Information
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Ecological Information
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MSDS Transport Information
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Regulatory Information
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Other Information
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HAZCOM Label
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MSDS NAME: 15596-026 TRIZOL REAGENT
Company: LIFE TECHNOLOGIES INC
Street: 8451 HELGERMAN CT
PO Box: 6009
City: GAITHERSBURG MD
Zipcode: 20884
Health Emergency Phone: 301-431-8585
Label Required IND: Y
Date Of Label Review: 12/16/1998
Status Code: C
Label Date: 12/16/1998
Origination Code: G
Hazard And Precautions: DEATH HAS BEEN REPORTED TO OCCUR W/IN 10 MINS AFTER
SKIN CONTACT. MAY BE FATAL IF ABSORBED THROUGH THE SKIN, INHALED/SWALLOWED.
CAUSES SEVERE BURNS TO SKIN, EYES, NOSE, THROAT, LUNGS/STOMACH. AREAS MA Y
BECOME DEEPLY ERODED & SCARRED. MAY DAMAGE CNS, KIDNEYS, LIVER, PANCREAS.
(SEE SUPP) CHEMICAL BURN, WATER/BLURRING OF
THE EYES, CONGESTION OF THE LUNGS/LIVER/KIDNEY/ SPLEEN. IRRITATION, SWEATING,
HEADACHE, THIRST, NAUSEA, ABDOMINAL PAIN, DIARRHEA, CYANOSIS, TWITCHING,
TREMORS, CONVULSIONS, COMA
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Disclaimer (provided with this information by the compiling agencies): This
information is formulated for use by elements of the Department of Defense.
The United States of America in no manner whatsoever expressly or implied
warrants, states, or intends said information to have any application, use or
viability by or to any person or persons outside the Department of Defense
nor any person or persons contracting with any instrumentality of the United
States of America and disclaims all liability for such use. Any person
utilizing this instruction who is not a military or civilian employee of the
United States of America should seek competent professional advice to verify
and assume responsibility for the suitability of this information to their
particular situation regardless of similarity to a corresponding Department
of Defense or other government situation.
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