INVITROGEN CORPORATION -- GUANIDINE HYDROCHLORIDE, 46-0061
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Material Safety Data Sheet
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MSDS Num: CJRSD
MSDS NAME: GUANIDINE HYDROCHLORIDE, 46-0061
Responsible Party
Name: INVITROGEN CORPORATION
Address: 1600 FARADAY AVENUE
City: CARLSBAD CA 92008
Info Phone: 800-955-6288
Emergency Phone Number: 800-451-8346
Resp. Party Other MSDS No.: 213
Review Ind: Y
Published: Y
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Contractor Summary
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Name: INVITROGEN CORPORATION (U.S. HEADQUARTERS)
Address: 1600 FARADAY AVENUE
City: CARLSBAD CA 92008
Phone: 800-955-6288
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Item Description Information
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Ingredients
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Cas: 50-01-1
RTECS #: MF4300000
Name: GUANIDINE HYDROCHLORIDE
Percent by Wt: 57.3
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Health Hazards Data
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LD50 LC50 Mixture: LD50:(ORAL,RAT) 475 MG/KG & TOX INFO.
Route Of Entry Inds - Inhalation: YES
Skin: YES
Ingestion: YES
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: ACUTE: CAUSES SEVERE IRRITATION. CHRONIC: HIGH
CONCENTRATIONS ARE EXTREMELY DESTRUCTIVE TO TISSUES OF MUCOUS MEMBRANES AND
UPPER RESPIRATORY TRACT, EYES AND SKIN. CAN CAUSE NERVOUS SYSTEM DISTURBANCES
. TARGET ORGAN DATA: BEHAVIORAL (ALTERED SLEEP TIME, EXCITEMENT);
GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA); BONE MARROW; NERVES.
First Aid: INGESTION: WASH OUT MOUTH WITH WATER. CONTACT MD IMMEDIATELY.
INHALATION: REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. SKIN: REMOVE CONTA
MINATED CLOTHING AND SHOES. WASH SKIN WITH SOAP AND COPIOUS AMOUNTS OF WATER.
EYES: IMMEDIATELY FLUSH EYES AND UNDER EYELIDS WITH COPIOUS AMOUNTS OF WATER
FOR AT LEAST 15 MINUTES. CONTACT MD.
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Handling and Disposal
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Spill Release Procedures: WEAR A NIOSH APPROVED RESPIRATOR, SAFETY GOGGLES,
RUBBER BOOTS AND GLOVES. SWEEP UP AND PLACE IN A BAG AND HOLD FOR WASTE
DISPOSAL. AVOID RAISING DUST.
Waste Disposal Methods: DISPOSE OF I/A/W ALL FEDERAL, STATE AND LOCAL
REGULATIONS.
Handling And Storage Precautions: STORE IN A TIGHTLY CLOSED CONTAINER IN A
COOL, DRY PLACE. AVOID INHALATION, EYE CONTACT, SKIN AND CLOTHING. TOXIC.
SEVERE IRRITANT.
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Fire and Explosion Hazard Information
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Flash Point Text: NO DATA AVAIL
Autoignition Temp Text: N/AV
Lower Limits: NOT AVAIL
Upper Limits: NOT AVAIL
Extinguishing Media: WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER, ALCOHOL
OR POLYMER FOAM.
Fire Fighting Procedures: USE NIOSH APPROVED SCBA AND FULL PROTECTIVE EQUIPMENT
(FP N).
Unusual Fire/Explosion Hazard: EMITS TOXIC FUMES UNDER THERMAL CONDITIONS.
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Control Measures
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Respiratory Protection: NIOSH APPROVED RESPIRATOR APPROPRIATE FOR EXPOSURE OF
CONCERN (FP N).
Protective Gloves: IMPERVIOUS GLOVES (FP N).
Eye Protection: ANSI APPROVED CHEMICAL WORKERS GOGGLES (FP N).
Other Protective Equipment: EYE WASH & DELUGE SHOWER MEETING ANSI DESIGN
CRITERIA (FP N).
Supplemental Safety and Health: PHYSICAL/CHEMICAL CHARACTS: WATER REACTIVE: NO
DATA AVAILABLE.
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Physical/Chemical Properties
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B.P. Text: NO DATA AVAILABLE
Melt/Freeze Pt: >181.C, 357.8F
M.P/F.P Text: 181-183C
Vapor Pres: NO DATA AVAILABLE
Vapor Density: NOT AVAIL
Spec Gravity: NO DATA AVAILABLE
Evaporation Rate & Reference: NO DATA AVAILABLE
Solubility in Water: SOLUBLE
Appearance and Odor: WHITE CRYSTALLINE POWDER.
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: MOISTURE.
Materials To Avoid: STRONG OXIDIZING AGENTS, PROTECT FROM MOISTURE.
Hazardous Decomposition Products: HAZARDOUS COMPOSTION PRODUCTS: TOXIC FUMES OF
CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN OXIDES AND HYDROGEN CHLORIDE GAS.
Hazardous Polymerization Indicator: NO
Conditions To Avoid Polymerization: WILL NOT OCCUR.
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Toxicological Information
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Toxicological Information: ANIMAL TOXICITY: LD50:(IPR,MUS) 500 MG/KG.
LDLO:(SCU,RAT) 404 MG/KG. LDLO:(ORAL,MAM) 300 MG/KG. IRRITANT DATA: NO DATA
AVAILABLE.
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Other Information
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Other Information: MFR'S FAX NUMBER: (760) 603-7201. PRODUCT DESCRIPTION:
XPRESS - GUANIDIUM.
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HAZCOM Label
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MSDS NAME: GUANIDINE HYDROCHLORIDE, 46-0061
Company: INVITROGEN CORPORATION (U.S. HEADQUARTERS)
Street: 1600 FARADAY AVENUE
City: CARLSBAD CA
Zipcode: 92008
Health Emergency Phone: 800-451-8346
Label Required IND: Y
Date Of Label Review: 09/28/1999
Status Code: A
Origination Code: F
Chronic Hazard IND: Y
Eye Protection IND: YES
Skin Protection IND: YES
Signal Word: DANGER
Respiratory Protection IND: YES
Health Hazard: Severe
Contact Hazard: Severe
Fire Hazard: Slight
Reactivity Hazard: None
Hazard And Precautions: ACUTE: CAUSES SEVERE IRRITATION. CHRONIC: HIGH
CONCENTRATIONS ARE EXTREMELY DESTRUCTIVE TO TISSUES OF MUCOUS MEMBRANES AND
UPPER RESPIRATORY TRACT, EYES AND SKIN. CAN CAUSE NERVOUS SYSTEM DISTURBANCES
. TARGET ORGAN DATA: BEHAVIORAL (ALTEREDSLEEP TIME, EXCITEMENT);
GASTROINTESTINAL (HYPERMOTILITY, DIARRHEA); BONE MARROW; NERVES.
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