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MSDS  : BRL 2333,AMOXIL
CAS  : 61336-70-7
NAME  : amoxycillin trihydrate
===================== Product Identification =====================

MSDS NAME:BRL 2333,AMOXIL
NIIN:01-011-1464
MSDS Number: BWLDM
=== Responsible Party ===
Company:SMITHKLINE BEECHAM PHARMACEUTICALS RESEARCH & DEVE
Address:709 SWEDELAND RD
Box:1539
City:KING OF PRUSSIA
State:PA
ZIP:19406-7400
Country:US
Info Phone Num:215-270-7300/7400
Emergency Phone Num:215-270-7300/7400
CAGE:0P1L6
=== Contractor Identification ===
Company:BEECHAM LABORATORIES
Box:City:CHICAGO
State:IL
ZIP:60675
Phone:(800) 251-7040
CAGE:04683
Company:SMITHKLINE BEECHAM PHARMACEUTICALS RESEARCH & DEVE
Address:709 SWEDELAND RD
Box:1539
City:KING OF PRUSSIA
State:PA
ZIP:19406
Country:US
Phone:215-270-6110
CAGE:0P1L6

============= Composition/Information on Ingredients =============

Name:AMOXYCILLIN TRIHYDRATE
CAS:61336-70-7
RTECS #:XH8310000
Fraction by Wt: 100%
Other REC Limits:1 MG/M3 8HR TWA, MFR

===================== Hazards Identification =====================

LD50 LC50 Mixture:LD50 (ORAL, RAT) IS >15,000 MG/KG.
Routes of Entry: Inhalation:YES Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:TARGET ORGANS:EYES, SKIN, RESPIRATORY
& GI TRACTS. ACUTE- MAY CAUSE EYE AND SKIN IRRITATION. INHALATION
MAY CAUSE ALLERGIC REACTION SUCH AS SNEEZING, COUGHING. MAY CAUSE
ALLERGIC REACTION IN SENSITIVE INDIVIDUAL BY INGESTION. MAY CAUSE
NAUSEA, VOMITING, DIARRHEA. CONTACT WITH SKIN MAY CAUSE RASH.
CHRONIC- UNKNOWN.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:EYES, SKIN IRRITATION; SKIN ITCHING, REDNESS,
SWELLING OF THE LIPS AND TONGUE OR FACE, RASH; EYE REDNESS AND
SWELLING; NAUSEA, VOMITING, DIARRHEA, COUGHING, SHORTNESS OF
BREATH, RUNNING NOSE, WHEEZING , DIFFICULTY IN BREATHING, STOMACH
DISCOMFORT, SORE OR DRY MOUTH OR SORE TONGUE
Medical Cond Aggravated by Exposure:INDIVIDUAL WITH KNOWN SENSITIVITY
TO PENICILLIN OR CEPHALOSPORIN ANTIBIOTICS MIGHT BE SENSITIVE TO
THIS PRODUCT.

======================= First Aid Measures =======================

First Aid:CALL A DOCTOR IF SYMPTOMS PERSIST. EYE:IMMEDIATELY FLUSH WITH
WATER FOR 15 MINUTES, HOLDING EYELIDS OPEN. SKIN:WASH WITH SOAP &
WATER. INHALED:REMOVE TO FRESH AIR. PROVIDE CPR/OXYGEN IF NEEDED.
ORAL:D ECISION TO INDUCE VOMITING MUST BE MADEBY A QUALIFIED
MEDICAL PERSONNEL. CALL A PHYSICIAN/POISON CONTROL CENTER
IMMEDIATELY. NOTE TO PHYSICIAN:TREAT AS AN OVERDOSAGE OF PENICILLIN
ANTIBIOTICS.

===================== Fire Fighting Measures =====================

Flash Point:NONE
Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, FOAM OR DRY CHEMICAL.
USE WATER SPRAY TO COOL FIRE EXPOSED CONTAINERS.
Fire Fighting Procedures:WEAR PROTECTIVE CLOTHING AND NIOSH-APPROVED
SELF-CONTAINED BREATHING APPARATUS. MOVE CONTAINERS FROM FIRE AREA
IF POSSIBLE WITHOUT PERSONAL RISK.
Unusual Fire/Explosion Hazard:AS WITH ANY FINELY DIVIDED ORGANIC SOLID,
DUST MAY BE EXPLOSIVE IF MIXED WITH AIR IN CRITICAL PROPORTIONS &
IN THE PRESENCE OF AN IGNITION SOURCE.

================== Accidental Release Measures ==================

Spill Release Procedures:WEAR PROTECTIVE EQUIPMENT. CAREFULLY SCOOP OR
SHOVEL SPILLED MATERIAL INTO A SUITABLY LABELLED CONTAINER FOR
RECOVERY OR DISPOSAL. AVOID GENERATING DUST. WASH DOWN SPILLAGE
AREA WITH LARGE AMOUNT OF W ATER TO ON-SITE WASTE WATER TREATMENT
SYSTEM.
Neutralizing Agent:NOT RELEVANT

====================== Handling and Storage ======================

Handling and Storage Precautions:STORE IN COOL (LESS THAN 86F), DRY,
TIGHTLY CLOSED CONTAINER, AWAY FROM MOISTURE AND SUNLIGHT. KEEP OUT
OF REACH OF CHILDREN.
Other Precautions:AS A GENERAL RULE, WHEN HANDLING PHARMACEUTICAL
PRODUCTS, AVOID ALL FORMS OF CONTACT AND INHALATION OF DUST, FUMES,
MISTS, AND/OR VAPORS ASSOCIATED WITH THE PRODUCT. GROUND ALL
EQUIPMENTS.

============= Exposure Controls/Personal Protection =============

Respiratory Protection:NONE NORMALLY REQUIRED. IF DUST PRESENT, WEAR
NIOSH-APPROVED DUST MASK OR RRESPIRATOR.
Ventilation:LOCAL EXHAUST RECOMMENDED FOR DUSTY SITUATION
Protective Gloves:DISPOSABLE SURGICAL LATEX GLOVES
Eye Protection:DUST-RESISTANT SAFETY GOGGLES
Other Protective Equipment:EYE WASH STATION, SAFETY SHOWER, PROTECTIVE
CLOTHING AND/OR UNIFORM
Work Hygienic Practices:OBSERVE GOOD PERSONAL HYGIENE PRACTICES AND
RECOMMENDED PROCEDURES. WASH HANDS AFTER HANDLING.
Supplemental Safety and Health

================== Physical/Chemical Properties ==================

HCC:T6
NRC/State Lic Num:NOT RELEVANT
Boiling Pt:B.P. Text:DECOMPOSES
Vapor Pres:NEGLIGIBLE
pH:3.5-6
Viscosity:NOT RELEVANT
Evaporation Rate & Reference:NOT RELEVANT
Solubility in Water:SLIGHT
Appearance and Odor:WHITE OR ALMOST WHITE CRYSTALLINE POWDER - ODORLESS

================= Stability and Reactivity Data =================

Stability Indicator/Materials to Avoid:YES
WATER
Stability Condition to Avoid:EXCESSIVE HEAT, DIRECT SUNLIGHT,
GENERATION OF DUST
Hazardous Decomposition Products:TOXIC GASES INCLUDING CARBON MONOXIDE,
CARBON DIOXIDE, OXIDES OF SULPHUR AND NITROGEN ARE EXPECTED.

==================== Disposal Considerations ====================

Waste Disposal Methods:RECOVER OR RECYCLE IF POSSIBLE. DISPOSAL SHOULD
BE IN ACCORDANCE WITH ALL LOCAL, STATE AND FEDERAL REGULATIONS.
RECOMMENDED PROCEDURE IS BY INCINERATION.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

*** END OF RECORD ***
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BRL 2333,AMOXIL 61336-70-7
LAROTID,19167,19980 61336-70-7

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