TM
Xpert EV鈩?
Material Safety Data Sheet
Effective Date: December 2005
1. Product and Company Information
Product name: Xpert EV鈩?
Common name: Not applicable
Compound name: Not applicable
Manufacturer: Telephone Numbers:
Cepheid (888) 838-3222
904 Caribbean Drive 24-Hour Emergency Telephone:
Sunnyvale, CA 94089 CHEMTREC (800) 424-9300
USA
2. Composition/Hazardous Ingredients
This product consists of a cartridge with five reagent beads to which aqueous reagent
solutions are added as part of an assay.
HAZARDOUS INGREDIENTS:
CAS# Chemical Name OSHA PEL
64-17-5 Ethanol 1000 ppm
69-65-8 D-Mannitol N/A
593-84-0 Guanidine Thiocyanate N/A
616-91-1 N-Acetyl-L-Cysteine N/A
7447-40-7 Potassium Chloride N/A
25322-68-3 Polyethylene Glycol (PEG 8000) N/A
75277-39-3 HEPES Salt N/A
3. Hazards Identification
Emergency Overview
Caution! May cause irritation to eye, skin irritation, and respiratory tract. Harmful if
swallowed or inhaled.
300-4075 Rev A Page 1
TM
Xpert EV鈩?
Material Safety Data Sheet
Effective Date: December 2005
POTENTIAL HEALTH EFFECTS:
Eye: May cause eye irritation.
Skin: May cause skin irritation.
Ingestion: Contains toxic components. May cause irritation of the digestive tract. At
very high doses, may cause vomiting, disorientation, weakness, low blood pressure,
convulsions, and death.
Inhalation: May cause irritation of the respiratory tract.
Chronic: No information found.
NFPA Hazard Rating (estimated): Health 3; Flammability 3; Instability: 0
4. First Aid Measures
Eye: Flush thoroughly with running water. Get medical advice if irritation
develops.
Skin: Wash skin with soap and plenty of water. Remove contaminated clothing
and wash before reuse. Get medical advice if irritation develops or
persists.
Ingestion: If swallowed, wash out mouth with water provided person is conscious.
Never give anything by mouth to an unconscious person. Get medical
attention. Do not induce vomiting unless directed to do so by medical
personnel.
Inhalation: Remove to fresh air and get medical attention for any breathing difficulty.
5. Fire Fighting Measures
General Information: Binding Reagent is flammable and other components may be
combustible.
Lysis Reagent may emit toxic and flammable fumes of cyanide in a fire. As in any fire,
wear self-contained breathing apparatus in pressure-demand (MSHA/NIOSH
approved or equivalent) and full protective gear.
Extinguishing Media: Dry chemical or carbon dioxide.
Flash Point: Not available.
Auto-ignition Temperature: Not available.
Explosion: Not considered an explosion hazard.
Explosion Limits, Upper: Not available.
NFPA Rating (estimated): Health: 3; Flammability: 3; Instability: 0
300-4075 Rev A Page 2
TM
Xpert EV鈩?
Material Safety Data Sheet
Effective Date: December 2005
6. Accidental Release Measures
Turn off potential ignition sources. Use proper personal protective equipment as
indicated in Section 8. Absorb liquids with inert material and sweep up loose solids.
Place residues in a suitable container for waste disposal. After removal, ventilate
contaminated area and flush thoroughly with water.
7. Handling and Storage
Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion. Keep
container tightly closed and store away from incompatible substances or from sources of
heat or ignition. Do not reuse container. Containers may be hazardous when empty.
8. Exposure Controls/Personal Protection
Exposure Limits: None established.
PERSONAL PROTECTIVE EQUIPMENT:
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure. Wash hands in case
of contact.
Respirators: Depending on actual exposure conditions, use of a respirator in accordance
with 29 CFR 1910.134 may be necessary.
Ventilation: A system of local or general exhaust is recommended.
Work Practices: Facilities storing or using this product should be equipped with an
eyewash station and a safety shower.
9. Physical and Chemical Properties
Appearance: Cartridge containing reagent white beads and clear aqueous reagents.
Physical State: Solid and liquid components.
Odor: Odorless. pH: 6-8 (Liquid reagents).
Vapor Pressure: Not applicable. Vapor Density: Not applicable.
300-4075 Rev A Page 3
TM
Xpert EV鈩?
Material Safety Data Sheet
Effective Date: December 2005
Evaporation Rate: Not applicable. Viscosity: Not applicable.
Boiling Point: Not applicable. Freezing/Melting Point: Not applicable.
Decomposition Temperature: No data. Solubility: Not applicable.
Specific Gravity/Density: Not available. Molecular Formula: Not applicable.
Molecular Weight: Not applicable.
10. Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, heat, flames, ignition sources.
Incompatibilities with Other materials: Strong oxidizing agents, peroxides, strong
acids and bases, acid chlorides, acid anhydrides, alkali metals, ammonia.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen
oxides, sulfur oxides, potassium oxides, hydrogen chloride, cyanide.
Hazardous Polymerization: Will not occur.
11. Toxicological Information
CAS # Name LD50/LC50 Carcinogenicity
64-17-5 Ethanol Oral rat LD50: 7060 mg/kg NTP - No
69-65-8 D-Mannitol Oral rat LD50: 13500 mg/kg NTP - No
593-84-0 Guanidine Thiocyanate No data found. NTP - No
616-91-1 N-Acetyl-L-Cysteine Oral rat LD50: 5050 mg/kg NTP - No
7447-40-7 Potassium Chloride Oral rat LD50: 2600 mg/kg NTP - No
Oral rat LD50: >30000 mg/kg NTP - No
Polyethylene Glycol (PEG
25322-68-3 (estimated from data for PEG 6000
8000)
and PEG 20000)
75277-39-3 HEPES Salt No data found. NTP - No
(Only select data presented here. See Registry of Toxic Effects of Chemical Substances
database for complete information.)
Other: The toxicological effects of this product have not been fully investigated.
300-4075 Rev A Page 4
TM
Xpert EV鈩?
Material Safety Data Sheet
Effective Date: December 2005
12. Ecological Information
Ecotoxicity: No data found.
Environmental Fate: No data found.
13. Disposal Considerations
Dispose of in accordance with all federal, state, and local waste regulations.
14. Transport Information
Transport in accordance with all federal, state, and local transportation regulations. May
qualify for small quantity exemptions.
15. Regulatory Information
CERCLA SARA 302 SARA 313
CAS# Name
RQ EHS
64-17-5 Ethanol No No No
69-65-8 D-Mannitol No No No
593-84-0 Guanidine Thiocyanate No No No
616-91-1 N-Acetyl-L-Cysteine No No No
7447-40-7 Potassium Chloride No No No
25322-68-3 Polyethylene Glycol (PEG 8000) No No No
75277-39-3 HEPES Salt No No No
300-4075 Rev A Page 5
TM
Xpert EV鈩?
Material Safety Data Sheet
Effective Date: December 2005
16. Other Information
Cepheid makes no warranties as to the accuracy or completeness of this information and
disclaims any liability in connection with its use. Cepheid鈥檚 obligations shall be only as
set forth in Cepheid鈥檚 standard terms and conditions of sale for this product. In no case
will Cepheid be liable for any incidental, indirect or consequential damages arising out
of the sale, resale, use or misuse of the product.
300-4075 Rev A Page 6
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