**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| Not available |Rabbit Brain Extract | <0.9% | unlisted |
|----------------|--------------------------------------|----------|-----------|
| 7365-45-9 |HEPES | 0.50% | 230-907-9 |
|----------------|--------------------------------------|----------|-----------|
| 7647-14-5 |Sodium chloride | 0.21 % | 231-598-3 |
|----------------|--------------------------------------|----------|-----------|
| 9002-92-0 |Brij-35 | 0.05% | unlisted |
|----------------|--------------------------------------|----------|-----------|
| Not available |BSA Fraction V | 0.84% | unlisted |
|----------------|--------------------------------------|----------|-----------|
| 10043-52-4 |Calcium chloride | 0.11 % | 233-140-8 |
|----------------|--------------------------------------|----------|-----------|
| 25322-68-3 |Polyethylene glycol | 0.29% | unlisted |
|----------------|--------------------------------------|----------|-----------|
| 26628-22-8 |Sodium azide | 0.08% | 247-852-1 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: None Listed.
Risk Phrases: None Listed.
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea.
Inhalation:
May cause respiratory tract irritation.
Chronic:
No information found.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Wash hands before eating. Remove
contaminated clothing and wash before reuse. Use with adequate
ventilation. Minimize dust generation and accumulation. Avoid
contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool place in the original container and protect from
sunlight. Keep container closed when not in use.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Good general ventilation should be sufficient to control airborne
levels. Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower.
Exposure Limits
CAS# 0-01-1:
CAS# 7365-45-9:
CAS# 7647-14-5:
Russia: 5 mg/m3 TWA
CAS# 9002-92-0:
CAS# 9048-46-1:
CAS# 10043-52-4:
CAS# 25322-68-3:
Germany: 1000 mg/m3 TWA (inhalable fraction)
Netherlands: 1000 mg/m3 MAC
CAS# 26628-22-8:
United Kingdom, WEL - TWA: 0.1 mg/m3 TWA (as NaN3)
United Kingdom, WEL - STEL: 0.3 mg/m3 STEL (as NaN3)
Belgium - TWA: 0.1 mg/m3 VLE
Belgium - STEL: 0.30 mg/m3 VLE
France - VLE: 0.1 ppm VLE; 0.3 mg/m3 VLE
Germany: 0.2 mg/m3 TWA
Malaysia: 0.29 mg/m3 Ceiling (as sodium azide); 0.11 ppm Ceiling
hydrazoic acid vapour
Netherlands: 0.3 mg/m3 STEL
Netherlands: 0.1 mg/m3 MAC
Spain: 0.1 mg/m3 VLA-ED
Spain: 0.3 mg/m3 VLA-EC; 0.1 ppm VLA-EC (as hydrazoic acid vapor)
0.18 mg/m3 VLA-EC (a
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid
Color: white
Odor: Odorless.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble in water.
Specific Gravity/Density: Not available.
Molecular Formula: Not applicable.
Molecular Weight:
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, incompatible materials.
Incompatibilities with Other Materials:
Strong oxidants.
Hazardous Decomposition Products:
No data available.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 0-01-1 unlisted.
CAS# 7365-45-9: TL6809000
CAS# 7647-14-5: VZ4725000
CAS# 9002-92-0: JR5960000 JR5970000 JR5990000 MD0875000
CAS# 9048-46-1 unlisted.
CAS# 10043-52-4: EV9800000
CAS# 25322-68-3: TQ3500000 TQ3520000 TQ3560000 TQ3580000
TQ3600000 TQ3610000 TQ3620000 TQ3630000 TQ3650000
TQ3675000 TQ3700000 TQ3800000 TQ3850000 TQ4025000
TQ4026000 TQ4027000 TQ4028000 TQ4030000 TQ4040000
TQ4041000 TQ4050000 TQ4070000 TQ4100000 TQ4105000
TQ4110000 TQ4950000 TQ5090000 TR1579850 ZD2465300
CAS# 26628-22-8: VY8050000
LD50/LC50:
Not available.
Not available.
CAS# 7647-14-5: Draize test, rabbit, eye: 100 mg Mild; Draize test,
rabbit, eye: 100 mg/24H Moderate; Draize test, rabbit, eye: 10 mg
Moderate; Draize test, rabbit, skin: 50 mg/24H Mild; Draize test,
rabbit, skin: 500 mg/24H Mild; Inhalation, rat: LC50 = >42 gm/m3/1H;
Oral, mouse: LD50 = 4 gm/kg; Oral, rat: LD50 = 3000 mg/kg; Skin,
rabbit: LD50 = >10 gm/kg.
CAS# 9002-92-0: Draize test, rabbit, eye: 10 mg; Draize test,
rabbit, eye: 100 mg; Draize test, rabbit, eye: 750 ug/24H Severe;
Draize test, rabbit, skin: 100 mg; Draize test, rabbit, skin: 500
mg/24H Mild; Draize test, rabbit, skin: 75 mg/24H Mild; Draize test,
rabbit, skin: 500 mg/24H Moderate; Oral, mouse: LD50 = 4940 mg/kg;
Oral, mouse: LD50 = 1170 mg/kg; Oral, mouse: LD50 = 3500 mg/kg;
Oral, mouse: LD50 = 1170 mg/kg; Oral, rat: LD50 = 8600 mg/kg; Oral,
rat: LD50 = 4150 mg/kg; Oral, rat: LD50 = 8600 mg/kg; Oral, rat:
LD50 = 1 gm/kg.
CAS# 9048-46-1.
CAS# 10043-52-4: Oral, mouse: LD50 = 1940 mg/kg; Oral, rabbit: LD50
= 1384 mg/kg; Oral, rat: LD50 = 1 gm/kg.
CAS# 25322-68-3: Draize test, rabbit, eye: 500 mg/24H Mild; Draize
test, rabbit, eye: 100 uL Mild; Draize test, rabbit, eye: 500 mg
Mild; Draize test, rabbit, eye: 500 mg Mild; Draize test, rabbit,
eye: 500 mg Mild; Draize test, rabbit, eye: 500 mg Mild; Draize
test, rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, eye: 500
mg/24H Mild; Draize test, rabbit, eye: 500 mg Mild; Draize test,
rabbit, eye: 500 mg/24H Mild; Draize test, rabbit, skin: 500 mg/24H
Mild; Draize test, rabbit, skin: 500 mg/24H Mild; Draize test,
rabbit, skin: 500 mg Mild; Oral, mouse: LD50 = 34 gm/kg; Oral,
mouse: LD50 = 31 gm/kg; Oral, mouse: LD50 = 28915 mg/kg; Oral, mouse:
LD50 = 36 gm/kg; Oral, rabbit: LD50 = 17300 mg/kg; Oral, rabbit: LD50
= 76 gm/kg; Oral, rabbit: LD50 = 14 gm/kg; Oral, rabbit: LD50 = 17300
mg/kg; Oral, rabbit: LD50 = 26800 mg/kg; Oral, rabbit: LD50 = 19
gm/kg; Oral, rabbit: LD50 = 28900 mg/kg; Oral, rabbit: LD50 = 76
gm/kg; Oral, rat: LD50 = 28 gm/kg; Oral, rat: LD50 = 31640 mg/kg;
CAS# 26628-22-8: Inhalation, mouse: LC50 = 32400 ug/m3; Inhalation,
rat: LC50 = 37 mg/m3; Oral, mouse: LD50 = 27 mg/kg; Oral, rat: LD50
= 27 mg/kg; Skin, rabbit: LD50 = 20 mg/kg; Skin, rat: LD50 = 50
mg/kg.
Carcinogenicity:
Rabbit Brain Extract -
Not listed by ACGIH, IARC, or NTP.
HEPES -
Not listed by ACGIH, IARC, or NTP.
Sodium chloride -
Not listed by ACGIH, IARC, or NTP.
Brij-35 -
Not listed by ACGIH, IARC, or NTP.
BSA Fraction V -
Not listed by ACGIH, IARC, or NTP.
Calcium chloride -
Not listed by ACGIH, IARC, or NTP.
Polyethylene glycol -
Not listed by ACGIH, IARC, or NTP.
Sodium azide -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: III
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: III
USA RQ: CAS# 26628-22-8: 1000 lb final RQ; 454 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 0-01-1: No information available.
CAS# 7365-45-9: No information available.
CAS# 7647-14-5: 0
CAS# 9002-92-0: 2
CAS# 9048-46-1: No information available.
CAS# 10043-52-4: 0
CAS# 25322-68-3: 1
CAS# 26628-22-8: 2
Canada
CAS# 7365-45-9 is listed on Canada's DSL List.
CAS# 7647-14-5 is listed on Canada's DSL List.
CAS# 9002-92-0 is listed on Canada's DSL List.
CAS# 10043-52-4 is listed on Canada's DSL List.
CAS# 25322-68-3 is listed on Canada's DSL List.
CAS# 26628-22-8 is listed on Canada's DSL List.
CAS# 0-01-1 is not listed on Canada's Ingredient Disclosure List.
CAS# 7365-45-9 is not listed on Canada's Ingredient Disclosure List.
CAS# 7647-14-5 is not listed on Canada's Ingredient Disclosure List.
CAS# 9002-92-0 is listed on Canada's Ingredient Disclosure List.
CAS# 9048-46-1 is not listed on Canada's Ingredient Disclosure List.
CAS# 10043-52-4 is not listed on Canada's Ingredient Disclosure List.
CAS# 25322-68-3 is not listed on Canada's Ingredient Disclosure List.
CAS# 26628-22-8 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 0-01-1 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 7365-45-9 is listed on the TSCA inventory.
CAS# 7647-14-5 is listed on the TSCA inventory.
CAS# 9002-92-0 is listed on the TSCA inventory.
CAS# 9048-46-1 is not listed on the TSCA inventory.
It is for research and development use only.
CAS# 10043-52-4 is listed on the TSCA inventory.
CAS# 25322-68-3 is listed on the TSCA inventory.
CAS# 26628-22-8 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
Text for R-phrases from Section 2
MSDS Creation Date: 9/02/1997 Revision #3 Date: 4/30/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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