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MSDS 
:
 Universal Coagulation Reference Plasma
CAS 
:
 1310-73-2
SYNONYMS 
:
 None.
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 1310-73-2 |Sodium hydroxide | 0.08% | 215-185-5 |
|----------------|--------------------------------------|----------|-----------|
| 7365-45-9 |HEPES | 0.4% | 230-907-9 |
|----------------|--------------------------------------|----------|-----------|
| 7447-41-8 |Lithium chloride | 0.04% | 231-212-3 |
|----------------|--------------------------------------|----------|-----------|
| 9011-04-5 |Polybrene | 0.001% | unlisted |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Not available.

Potential Health Effects
Eye:
May cause eye irritation.
Skin:
Prolonged and/or repeated contact may cause irritation and/or
dermatitis. Product tests non-reactive for HBsAg and negative for
antibodies to HIV and HCV. However, material should be handled as
potentially infectious.
Ingestion:
May cause irritation of the digestive tract.
Inhalation:
Prolonged exposure may result in dizziness and general weakness.
Chronic:
No information found.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of soap and water.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
In case of spill, sweep up solid or absorb liquid with inert
material, then place into a biohazard container. Wear protective
equipment.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid
contact with skin and eyes. Avoid ingestion and inhalation.
Storage:
Store in a cool place in the original container and protect from
sunlight.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Good general ventilation should be sufficient to control airborne
levels.
Exposure Limits
CAS# 1310-73-2:
United Kingdom, WEL - STEL: 2 mg/m3 STEL
United States OSHA: 2 mg/m3 TWA
Belgium - TWA: 2 mg/m3 VLE
France - VME: 2 mg/m3 VME
Germany: 2 mg/m3 TWA (inhalable fraction)
Japan: 2 mg/m3 Ceiling
Malaysia: 2 mg/m3 Ceiling
Spain: 2 mg/m3 VLA-EC
CAS# 7365-45-9:

CAS# 7447-41-8:

CAS# 9011-04-5:


Personal Protective Equipment

Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Solid
Color: white
Odor: Odorless.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Not available.
Specific Gravity/Density: Not available.
Molecular Formula: Not applicable.
Molecular Weight:

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
None reported.
Incompatibilities with Other Materials:
None reported.
Hazardous Decomposition Products:
None.
Hazardous Polymerization: Has not been reported

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 1310-73-2: WB4900000
CAS# 7365-45-9: TL6809000
CAS# 7447-41-8: OJ5950000
CAS# 9011-04-5: MO1400000
LD50/LC50:
CAS# 1310-73-2: Draize test, rabbit, eye: 400 ug Mild; Draize test,
rabbit, eye: 1% Severe; Draize test, rabbit, eye: 50 ug/24H Severe;
Draize test, rabbit, eye: 1 mg/24H Severe; Draize test, rabbit,
skin: 500 mg/24H Severe.
CAS# 7365-45-9.
CAS# 7447-41-8: Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 500 mg/24H Severe; Oral, mouse: LD50 =
1165 mg/kg; Oral, mouse: LD50 = 1165 mg/kg; Oral, rabbit: LD50 = 800
mg/kg; Oral, rabbit: LD50 = 775 mg/kg; Oral, rat: LD50 = 526 mg/kg;
Oral, rat: LD50 = 1530 mg/kg; Skin, rabbit: LD50 = 1629 mg/kg; Skin,
rat: LD50 = 1488 mg/kg.
CAS# 9011-04-5.
Carcinogenicity:
Sodium hydroxide -
Not listed by ACGIH, IARC, or NTP.
HEPES -
Not listed by ACGIH, IARC, or NTP.
Lithium chloride -
Not listed by ACGIH, IARC, or NTP.
Polybrene -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****



**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Shipping Name: CORROSIVE SOLID, N.O.S.*
Hazard Class: 8
UN Number: 1759
Packing Group: II
IMO
Shipping Name: CORROSIVE SOLID, N.O.S.
Hazard Class: 8
UN Number: 1759
Packing Group: II
RID/ADR
Shipping Name: CORROSIVE SOLID, N.O.S.
Hazard Class: 8
UN Number: 1759
Packing group: II
USA RQ: CAS# 1310-73-2: 1000 lb final RQ; 454 kg final RQ

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 1310-73-2: 1
CAS# 7365-45-9: No information available.
CAS# 7447-41-8: 1
CAS# 9011-04-5: 2
Canada
CAS# 1310-73-2 is listed on Canada's DSL List.
CAS# 7365-45-9 is listed on Canada's DSL List.
CAS# 7447-41-8 is listed on Canada's DSL List.
CAS# 1310-73-2 is listed on Canada's Ingredient Disclosure List.
CAS# 7365-45-9 is not listed on Canada's Ingredient Disclosure List.
CAS# 7447-41-8 is not listed on Canada's Ingredient Disclosure List.
CAS# 9011-04-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1310-73-2 is listed on the TSCA inventory.
CAS# 7365-45-9 is listed on the TSCA inventory.
CAS# 7447-41-8 is listed on the TSCA inventory.
CAS# 9011-04-5 is not listed on the TSCA inventory.
It is for research and development use only.

**** SECTION 16 - ADDITIONAL INFORMATION ****

Text for R-phrases from Section 2
R 35 Causes severe burns.
MSDS Creation Date: 9/02/1997 Revision #5 Date: 2/06/2004

The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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ALL MSDS PAGES IN THIS GROUP
NAMECAS
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Factor VII Abnormal Control Level 2
Factor VII Abnormal Control Level 1
Factor VII Deficient Plasma 7365-45-9
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Factor V Abnormal Control Level 3
2-Chloro-4-Methylaniline, 98% 615-65-6
Guanidine acetate 593-87-3
Factor V Abnormal Control Level 2
Ammonium Sulfobetaine - 22.5 % Solution in Water 0-00-1
Thromboplastin-D 0-01-1
Universal Coagulation Reference Plasma 1310-73-2
4-Fluorobenzoic Acid, 99% 456-22-4
Eosin Y, 1 % Alcoholic 64-17-5
Methylsulfuric Acid Sodium Salt (Pract), 99% (Titr.) 512-42-5
Histomount T 108-88-3
1-Chloro-2,3-epoxypropane 106-89-8
2-Chloroethanol 107-07-3
4-Chloromercuribenzene sulfonic acid, sodium salt 14110-97-5
4-Chloro-7-nitrobenzofuazan 10199-89-0
Chloroauric Acid (51 % Au) 16903-35-8
2-Chlorophenol 95-57-8
Phenyltrimethylammonium tribromide, 97% 4207-56-1
4-Chorophenol 106-48-9
Chlorophenol Red 4430-20-0
N-Chlorosuccinimide 128-09-6
4-Chlorotoluene 106-43-4
Cinnamaldehyde 104-55-2
Cinnamic Acid 621-82-9
Citraconic Anhydride 616-02-4
L-Citrulline 372-75-8
Cobalt (II) Carbonate 12602-23-2
2,4,6-Collidine 108-75-8
Creatine Anhydrous 57-00-1
Creatinine 60-27-5
Cresol Mixed Isomers 1319-77-3
o-Cresolphthaleindi-(methyliminodi-acetic acid) 2411-89-4
m-Cresol Purple Solution 0.04 % 108-39-4
Cresol Red Solid 1733-12-6
Cresol Red Solution 0.02 % 64-17-5
o-Cresolsulfonphthaleindi-(methyliminodiacetic acid) disodium salt 1611-35-4
6-Methoxyquinaldine 1078-28-0
Crotonaldehyde 4170-30-3
12-Crown-4 ether 294-93-9
15-Crown-5 Ether 33100-27-5
18-Crown-6 Ether 17455-13-9
Copper (II) Acetate 142-71-2
n-(4-Chloroacetylphenyl)methanesulfonamide , 98% (uv-vis) 64488-52-4
(2R,3S)-1-Carboxy-4-Propyl-2,3-Dihydroxy-Cyclohexa-4,6-Diene, 0-01-1
Copper (II) Nitrate 3251-23-8

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