**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 367-25-9 |2,4-Difluoroaniline | 99 | 206-687-5 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: 20/21/22 36/37/38
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
May cause eye irritation. May cause chemical conjunctivitis and
corneal damage.
Skin:
Harmful if absorbed through the skin. May cause skin sensitization,
an allergic reaction, which becomes evident upon re-exposure to this
material. May cause irritation and dermatitis. May cause cyanosis of
the extremities.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. Methemoglobinemia is characterized by dizziness,
drowsiness, headache, shortness of breath, cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood),
rapid heart rate and chocolate-brown colored blood. Overexposure may
cause methemoglobinemia.
Inhalation:
May cause respiratory tract irritation. Aspiration may lead to
pulmonary edema. Methemoglobinemia is characterized by dizziness,
drowsiness, headache, shortness of breath, cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood),
rapid heart rate and chocolate-brown blood. Inhalation of aniline
causes anoxia due to the formation of methemoglobin. Inhalation at
high concentrations may cause CNS depression and asphixiation.
Chronic:
May cause methemoglobinemia, which is characterized by
chocolate-brown colored blood, headache, weakness, dizziness, breath
shortness, cyanosis (bluish skin due to deficient oxygenation of
blood), rapid heart rate, unconsciousness and possible death.
Repeated exposure may cause sensitization dermatitis.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene
Blue depending on the methemoglobin concentration in the blood.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Use water spray to keep fire-exposed containers
cool. Vapors may be heavier than air. They can spread along the
ground and collect in low or confined areas. Combustible liquid and
vapor. Approach fire from upwind to avoid hazardous vapors and toxic
decomposition products.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Avoid contact with eyes, skin, and clothing. Empty
containers retain product residue, (liquid and/or vapor), and can be
dangerous. Keep container tightly closed. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to
heat, sparks or open flames. Use only with adequate ventilation. Keep
away from heat, sparks and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Store in a tightly closed
container. Store in a cool, dry, well-ventilated area away from
incompatible substances. Isolate from oxidizing materials and acids.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 367-25-9:
Personal Protective Equipment
Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: clear brown
Odor: aniline-like
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 170 deg C @ 753mm Hg
Freezing/Melting Point: -7.5 deg C
Autoignition Temperature: > 600 deg C (> 1,112.00 deg F)
Flash Point: 62 deg C ( 143.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >500 deg C
Solubility in water: 20 G/L WATER (20 C)
Specific Gravity/Density: 1.2680g/cm3
Molecular Formula: C6H5F2N
Molecular Weight: 129.11
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Ignition sources, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, hydrogen fluoride gas, aniline.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 367-25-9: BX3680000
LD50/LC50:
CAS# 367-25-9: Inhalation, rat: LC50 = 6210 mg/m3/4H; Oral, rat:
LD50 = 820 mg/kg; Skin, rat: LD50 = 672 mg/kg.
Carcinogenicity:
2,4-Difluoroaniline -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: FLUOROANILINES
Hazard Class: 6.1
UN Number: 2941
Packing Group: III
IMO
Shipping Name: FLUOROANILINES
Hazard Class: 6.1
UN Number: 2941
Packing Group: III
RID/ADR
Shipping Name: FLUOROANILINES
Hazard Class: 6.1
UN Number: 2941
Packing group: III
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 20/21/22 Harmful by inhalation, in contact with
skin and if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 367-25-9: No information available.
Canada
CAS# 367-25-9 is listed on Canada's NDSL List.
CAS# 367-25-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 367-25-9 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 9/02/1997 Revision #5 Date: 5/13/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
4'-Isocyanato-5'-nitrobenzo-15-crown-5, 99.5%
| 83935-64-2 |
|
Trimethylacetonitrile, 98%
| 630-18-2 |
|
Thallium(iii) oxide, 99+%
| 1314-32-5 |
|
Methyl laurate, 96%
| 111-82-0 |
|
4-Methylsulphonylphenol,95%
| 14763-60-1 |
|
Triphenylmethanol, 97%
| 76-84-6 |
|
Methyl P-Nitrobenzenesulfonate
| 6214-20-6 |
|
4-Pentylbiphenyl, 99%
| 7116-96-3 |
|
Alpha, 4-Dimethyl-3-Hydroxyphenethylamine Hydrochloride, 98%
| 29440-90-2 |
|
2-Bromo-5-nitrotoluene, 99%
| 7149-70-4 |
|
4-Chloro-o-phenylenediamine, tech., 80+%
| 95-83-0 |
|
2-Hydroxyphenylacetic Acid, 99%
| 614-75-5 |
|
Tetramethylammonium tetrafluoroborate,97%
| 661-36-9 |
|
Hydroxyguanidine sulfate, hydrate, 99% (on the dry basis)
| 6345-29-5 |
|
1-Naphthylacetic acid, 99%
| 86-87-3 |
|
2,3',6-Trichloroindophenol sodium salt (pract)
| 6273-47-8 |
|
2-tert-Butyl-4-methylphenol, 99%
| 2409-55-4 |
|
1,3-Diacetylbenzene, 99%
| 6781-42-6 |
|
Diphenic Acid, 98%
| 482-05-3 |
|
L-Thyroxine, Sodium Salt Pentahydrate, 99%
| 6106-07-6 |
|
3-Amino-5,6-Dimethyl-1,2,4-Triazine, 97%
| 17584-12-2 |
|
1,1,2,2-Tetraethoxyethane, 99+%
| 3975-14-2 |
|
Coumarin 120, Laser Grade, 99% (UV-VIS)
| 26093-31-2 |
|
Toluidine Red
| 2425-85-6 |
|
Carbon tetrabromide, 99%
| 558-13-4 |
|
4,4'-Methylenebis(2-isopropyl-6-methylaniline), 98% (Titr.)
| 16298-38-7 |
|
3-Methylglutaric acid, 99%
| 626-51-7 |
|
2-Methyl-2-Butene
| 513-35-9 |
|
2,4-Difluoroaniline, 99%
| 367-25-9 |
|
3-Iodobenzoic acid, 98%
| 618-51-9 |
|
N,N-Dibutylformamide, 99+%
| 761-65-9 |
|
DL-Camphoroquinone, 99%
| 10373-78-1 |
|
4-Phenyltoluene, 98%
| 644-08-6 |
|
Chloro bis-(4-fluorophenyl)methane, 98%
| 27064-94-4 |
|
Diethylzinc, 15 wt.% solution in hexane
| 110-54-3 |
|
3-Phenoxybenzoic acid, 99%
| 3739-38-6 |
|
2-Chloro-5-(Fluorosulfonyl)-Benzoic Acid 99+%
| 21346-66-7 |
|
Cycloheptanone, 98%
| 502-42-1 |
|
DL-3-aminoisobutyric acid monohydrate , 99%
| 10569-72-9 |
|
3-Bromo-1,2-Propanediol, 97%
| 4704-77-2 |
|
3-Methylcholanthrene, 99%
| 56-49-5 |
|
Chrome Azurol S
| 1667-99-8 |
|
Amberlite xad-7 hp
| 37380-43-1 |
|
Trans-1-Methoxy-3-Trimethylsilyloxy-1,3- Butadiene
| 54125-02-9 |
|
2,3-Dibromothiophene,97%
| 3140-93-0 |
|
4-Nitrodiphenylamine, 98+%
| 836-30-6 |
|
Cesium nitrate, 99.99%
| 7789-18-6 |
|
(2R,3R)-1-Carboxy-2,3-Dihydroxy-4-Methylcyclohexa-3,5-Diene, 95%
| 0-01-1 |
|
1-Hexene, 97%
| 592-41-6 |
|
4,4'Diaminodiphenylamine Sulfate, Tech., 85%
| 53760-27-3 |
|
|