**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 485-49-4 |(+)-Bicuculline | 98 | 207-619-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 23/24/25
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed.Highly
toxic.The toxicological properties of this material have not been
fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be fatal if absorbed through the
skin.
Ingestion:
May be fatal if swallowed. May cause irritation of the digestive
tract. The toxicological properties of this substance have not been
fully investigated.
Inhalation:
May be fatal if inhaled. May cause respiratory tract irritation. The
toxicological properties of this substance have not been fully
investigated.
Chronic:
Prolonged exposure may cause non-specific nervous system effects.
Prolonged or repeated exposure may cause convulsions.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If breathing is difficult, give oxygen. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply
artificial respiration using oxygen and a suitable mechanical device
such as a bag and a mask.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam. Use
agent most appropriate to extinguish fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Clean up spills immediately, observing precautions in the
Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Minimize dust generation and
accumulation. Do not breathe dust, vapor, mist, or gas. Do not get in
eyes, on skin, or on clothing. Keep container tightly closed. Do not
ingest or inhale. Use only in a chemical fume hood. Wash clothing
before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep
refrigerated. (Store below 4C/39F.)
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use only under a
chemical fume hood.
Exposure Limits
CAS# 485-49-4:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: light yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 196 - 198 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C20H17NO6
Molecular Weight: 367.36
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stability unknown.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 485-49-4: LV0909840
LD50/LC50:
Not available.
Intraperitoneal, mouse: LD50 = 8480
Carcinogenicity:
(+)-Bicuculline -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2811
Packing Group: II
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: II
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: II
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
S 38 In case of insufficient ventilation, wear
suitable respiratory equipment.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 485-49-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 485-49-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 485-49-4 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 3/08/1999 Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
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| 6282-98-0 |
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M-Carborane
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|
3-Methoxyphenethylamine
| 2039-67-0 |
|
3,4-(Methylenedioxy)phenylacetic Acid, 98.5+% (Titr.)
| 2861-28-1 |
|
6-Amino-2-methyl-2-heptanol, 98%
| 372-66-7 |
|
6-Amino-2-Methyl-2-Heptanol Hydrochloride, 98+% (Titr.)
| 543-15-7 |
|
1-(3-Methoxyphenyl)-piperazine, 98%
| 16015-71-7 |
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Isopropyl-??-D-thiogalactopyranoside, DNase, RNase, Protease free
| 367-93-1 |
|
Duolite mb6113, non-regenerable mixed bed resin
| 7732-18-5 |
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Linolenic acid, 99%
| 463-40-1 |
|
Beta-Tetralone, 95%
| 530-93-8 |
|
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| 5787-71-3 |
|
DL-XYLOSE, 98%
| 41247-05-6 |
|
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| 305-01-1 |
|
Scopoletin, 95%
| 92-61-5 |
|
Sarcosine ethyl ester hydrochloride, 97+%
| 52605-49-9 |
|
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| 155-58-8 |
|
Pentaerythrityl Tetraacetate
| 597-71-7 |
|
L-4-Chlorophenylalanine, 98%
| 14173-39-8 |
|
(+)-Bicuculline, 98%
| 485-49-4 |
|
Phosphoenolpyruvic Acid, Monopotassium Salt, 99%
| 4265-07-0 |
|
N-(2-Aminoethyl)-Piperidine, 98%
| 27578-60-5 |
|
Coumarin 338, Laser Grade, 99% (UV-Vis)
| 62669-75-4 |
|
beta-D-Glucose pentaacetate, 98%
| 604-69-3 |
|
Harmine, 98%
| 442-51-3 |
|
l-Prolinamide, 98%
| 7531-52-4 |
|
Methyl carbamate, 99%
| 598-55-0 |
|
L-Proline methyl ester hydrochloride, 98%
| 2133-40-6 |
|
Phenyl-beta-d-galactopyranoside, 98%
| 2818-58-8 |
|
Dl-cystine, 99%
| 923-32-0 |
|
6-(Carbobenzyloxyamino)caproic acid, 98%
| 1947-00-8 |
|
2,5-Anhydro-D-Mannitol, 99%
| 41107-82-8 |
|
Cytidine 5'-Monophosphate, Disodium Salt Hydrate
| 6757-06-8 |
|
Beta-Alanine Ethyl Ester Hydrochloride, 98 %
| 4244-84-2 |
|
Ethyl (R)-(-)-2-pyrrolidone-5-carboxylate, 99%
| 68766-96-1 |
|
9-Fluorenylmethyl pentafluorophenyl carbonate, 98%
| 88744-04-1 |
|
2,3:5,6-Di-O-isopropylidine-alpha-D-mannofuranose, 98%
| 14131-84-1 |
|
o-(1,2-Dihydro-2-oxo-1-pyridyl)-n,n,n',n'- tetramethyluronium
| 125700-71-2 |
|
(s)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone, 97%
| 17342-08-4 |
|
L-Serinamide hydrochloride, 98%
| 65414-74-6 |
|
o-Benzotriazol-1-yl-n,n,n',n'-tetramethyluronium tetrafluoroborate,
| 125700-67-6 |
|
O-(n-succinimidyl)-n,n,n',n'-tetramethyl uronium tetrafluoroborate,
| 105832-38-0 |
|
Octafluoronaphthalene, 96%
| 313-72-4 |
|
n-(tert-Butoxycarbonyl)-l-laspartic acid, 99%
| 13726-67-5 |
|
n-alpha-Carbobenzyloxy-l-tryptophan, 99%
| 7432-21-5 |
|
l-Cysteine methyl ester hydrochloride, 98%
| 18598-63-5 |
|
N-Acetyl-5-Hydroxytryptamine, 99%
| 1210-83-9 |
|
DL-Tryptophan, 99+%
| 54-12-6 |
|
3-Bromobenzoic hydrazide, 98%
| 39115-96-3 |
|
2-Amino-5-bromobenzoic acid, 97%
| 5794-88-7 |
|
|