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MSDS  : Silane, trimethoxyvinyl-
CAS  : 2768-02-7
SYNONYMS  : * A 171 * A 171 (Silane derivative) * Ethenyltrimethoxysilane * KBM 1003 * Silane, ethenyltrimethoxy- * SZ 6300 * (Trimethoxysilyl)ethene * Trimethoxyvinylsilane * V 4917 * Vinyl trimethoxy silane * VTS-M * Y 4302
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : VV6770000
CHEMICAL NAME : Silane, trimethoxyvinyl-
CAS REGISTRY NUMBER : 2768-02-7
BEILSTEIN REFERENCE NO. : 1099136
REFERENCE : 4-04-00-04256 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 11
MOLECULAR FORMULA : C5-H12-O3-Si
MOLECULAR WEIGHT : 148.26
WISWESSER LINE NOTATION : 1U1-SI-O1&O1&O1
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* A 171
* A 171 (Silane derivative)
* Ethenyltrimethoxysilane
* KBM 1003
* Silane, ethenyltrimethoxy-
* SZ 6300
* (Trimethoxysilyl)ethene
* Trimethoxyvinylsilane
* V 4917
* Vinyl trimethoxy silane
* VTS-M
* Y 4302

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1224,1986

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1224,1986

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 7340 uL/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise
specified
Behavioral - somnolence (general depressed activity)
Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539432

TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2773 ppm
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation
Behavioral - somnolence (general depressed activity)
Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539432

TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3360 uL/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539432

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 400 ppm/14W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes
REFERENCE :
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert
Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)-
1978- Volume(issue)/page/year: 17,800,1989

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 750 ppm/6H/9D-I
TOXIC EFFECTS :
Behavioral - fluid intake
Kidney, Ureter, Bladder - hematuria
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0539432

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA Section 8(e) Risk Notification, 8EHQ-1292-8623

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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