*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : WZ1797000
CHEMICAL NAME : Terephthaloyl chloride
CAS REGISTRY NUMBER : 100-20-9
BEILSTEIN REFERENCE NO. : 0607796
REFERENCE : 4-09-00-03318 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 12
MOLECULAR FORMULA : C8-H4-Cl2-O2
MOLECULAR WEIGHT : 203.02
WISWESSER LINE NOTATION : GVR DVG
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* 1,4-Benzenedicarbonyl chloride
* 1,4-Benzenedicarbonyl dichloride
* p-Phenylenedicarbonyl dichloride
* p-Phthaloyl chloride
* p-Phthaloyl dichloride
* Terephthalic acid chloride
* Terephthalic acid dichloride
* Terephthalic dichloride
* Terephthaloyl dichloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York,
Academic Press, Inc., 1969 Volume(issue)/page/year: -,475,1969
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 700 mg/m3/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation
Lungs, Thorax, or Respiration - dyspnea
Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0533726
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2140 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(12),35,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 950 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(12),35,1984
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0533726
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 4168 mg/kg/26W-I
TOXIC EFFECTS :
Liver - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(12),40,1984
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 4122 mg/kg
SEX/DURATION : male 26 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(12),35,1984
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 4122 mg/kg
SEX/DURATION : female 26 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
Volume(issue)/page/year: 49(12),35,1984
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X4188
No. of Facilities: 27 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 212 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
Terephthalamide,N,N'-bis(1-methyl-4-piperidylmethyl)-, hemihydrate
| 10593-60-9 |
Terephthalamide, N,N'-bis(4-piperidylmethyl)-,hydrate
| 15234-94-3 |
Terephthalamide, N,N'-dimethyl-N,N'-dinitroso-
| 133-55-1 |
Terephthalamidine,N,N''-bis(p-(methylamidino)phenyl)-,tetrahydrochloride
| 2053-23-8 |
Sulfuric acid, zinc salt, basic
| 68813-94-5 |
Terephthalanilide,2-amino-4',4''-bis(N-methylamidino)-,trihydrochloride
| 68813-94-5 |
Terephthalanilide,2-amino-4',4''-bis(5-methyl-2-imidazolin-2-yl)-
| 4607-27-6 |
Terephthalanilide,4',4''-bis(2-imidazolin-2-ylamino)-
| 537-66-6 |
Terephthalanilide,4',4''-bis(2-imidazolin-2-yl)-2-chloro-
| 1820-92-4 |
Terephthalic acid
| 100-21-0 |
Terephthalic acid, compd. with3-(2-aminoethyl)indol-5-ol and acetate (1:2:2)
| 52671-02-0 |
Terephthalic acid, bis(3-dibutylaminopropyl) ester,hydrochloride
| 52671-02-0 |
Terephthalic acid, bis(2-diethylaminoethyl) ester,hydrochloride
| 52671-02-0 |
Terephthalic acid, bis(2-dimethylaminoethyl) ester,hydrochloride
| 52671-02-0 |
Terephthalic acid, bis(2-ethylhexyl) ester
| 6422-86-2 |
Sulfurous acid
| 7782-99-2 |
Terephthalic acid,bis(1-methyl-4-phenyl-4-piperidylmethyl) ester,dihydrochloride, hydrate
| 102339-08-2 |
Terephthalic acid, dibutyl ester
| 1962-75-0 |
Terephthalic acid, dicyclopentyl ester
| 18699-50-8 |
Terephthalic acid, didodecyl ester
| 18749-84-3 |
Terephthalic acid, diester with2-methyl-1-piperidinepropanol, hydrochloride
| 18749-84-3 |
Terephthalic acid, diethyl ester
| 636-09-9 |
Terephthalic acid, diisobutyl ester
| 18699-48-4 |
Terephthalic acid, diisopropyl ester
| 6422-84-0 |
Terephthalic acid, dimethyl ester
| 120-61-6 |
Terephthalic acid, dipentyl ester
| 1818-95-7 |
Sulfurous acid, bis(alpha-methylphenethyl) ester
| 74039-47-7 |
Terephthalic acid, dipropyl ester
| 1962-74-9 |
Terephthalic acid, disodium salt
| 10028-70-3 |
Terephthalic acid, 1,4-dithio-
| 1076-98-8 |
Terephthalic acid, 1,4-dithio-,S,S-bis(2,3-epithiopropyl) ester
| 1076-98-8 |
Terephthalic acid, compd. with dodecylguanidine (12)
| 19727-17-4 |
Terephthalic acid, tetrachloro-, dimethyl ester
| 1861-32-1 |
Terephthalic acid, 2,3,5,6-tetraiodo-,bis(2,3-dihydroxypropyl) ester
| 61838-99-1 |
Terephthalic acid, 2,3,5,6-tetraiodo-,bis(2-hydroxyethyl) ester
| 61838-98-0 |
Terephthalic acid, 2,3,5,6-tetraiodo-, dimethyl ester
| 61839-06-3 |
Terephthalohydroxamic acid
| 20073-80-7 |
Sulfurous acid, bis(2-propynyl) ester
| 1899-25-8 |
Terephthaloyl chloride
| 100-20-9 |
Tergitol anionic P-28
| 141-65-1 |
Tergitol 12-M-10 (nonionic)
| 12627-30-4 |
Tergitol minfoam
| 12627-30-4 |
Tergitol min-foam 1X
| 103331-86-8 |
Tergitol min-foam 2X
| 103331-86-8 |
Tergitol NP-14
| 9016-45-9 |
Tergitol NP-27
| 9016-45-9 |
Tergitol NP-33 (nonionic)
| 9016-45-9 |
Tergitol NP-35 (nonionic)
| 9016-45-9 |
Sulfurous acid, butyl 4-chloro-2-butynyl ester
| 74039-48-8 |
Tergitol NP-40 (nonionic)
| 9016-45-9 |
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