RTECS NUMBER : XH9425000
CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
3,3-dimethyl-7-oxo-6- (2-phenylacetamido)-, compd.
with N,N'-dibenzylethylenediamine (2:1)
CAS REGISTRY NUMBER : 1538-09-6
OTHER CAS REGISTRY NOS. : 12705-12-3
LAST UPDATED : 199707
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C32-H36-N4-O8-S2.C16-H20-N2
MOLECULAR WEIGHT : 909.22
WISWESSER LINE NOTATION : T45 ANV ESTJ CMV1R& F F GVQ & 2 &622
COMPOUND DESCRIPTOR : Drug
Reproductive Effector
SYNONYMS/TRADE NAMES :
* Beacillin
* Benzacillin
* Benzapen
* Benzathine benzylpenicillin
* Benzathine penicillin
* Benzathine penicillin G
* Benzethacil
* Benzylpenicillin benzathine
* Benzylpenicillin dibenzylethylenediamine salt
* Bica-penicillin
* Bicillin
* Cepacilina
* Cillenta
* Debecillin
* Debecylina
* Diamine penicillin
* Diaminocillina
* Dibencil
* Dibencillin
* N,N'-Dibenzylethylenediamine bis(benzyl penicillin)
* Dibenzylethylenediamine-di-penicillin G
* N,N'-Dibenzylethylenediamine, compounded with penicillin G (1:2)
* N,N'-Dibenzylethylenediamine salt of benzylpenicillin
* Durabiotic
* Dura-penita
* Duropenin
* Ethylenediamine, N,N'-dibenzyl-, compd. with penicillin G (1:2)
* Extencilline
* Extenicilline
* Lentocillin
* Lentopenil
* Leomypen
* Longacilina
* Longicil
* Megacillin suspension
* Moldamin
* NCI-C56100
* Neolin
* Penadur
* Penadur L-A
* Pendepon
* Pen-Di-Ben
* Penditan
* Penduran
* Penicillin G, benzathine
* Penicillin G, compd. with N,N'-dibenzylethylenediamine (2:1)
* Penicillin G salt of N,N'-dibenzylethylenediamine
* Penidural
* Penidure
* Permapen
* Tardocillin
* Vicin
* Wycillina
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,774,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 460 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC)
V.1-12, 1951-62. For publisher information, see CLMEA3.
Volume(issue)/page/year: 4,633,1954
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - rat
DOSE : 22905 ug/kg
SEX/DURATION : female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
REFERENCE :
BEXBAN Bulletin of Experimental Biology and Medicine (English Translation).
Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY
10013) V.41- 1956- Volume(issue)/page/year: 82,1076,1976
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - T1268
No. of Facilities: 49 (estimated)
No. of Industries: 1
No. of Occupations: 2
No. of Employees: 1896 (estimated)
No. of Female Employees: 921 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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