* Compocillin
* Hydrabamine penicillin G
* Penicillin G compd. with N,N'-bis(dehydroabietyl)ethylenediamine (2:1)
* Penicillin G hydrabamine
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : XH9801000
CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
3,3-dimethyl-7-oxo-6-((phenylacetyl)
amino)-2S-(2-alpha,5-alpha,6-beta))-, compd. with
(1R-(1-alpha(1R*,4aS*,10aR*),4a-beta,10a-
alpha))-N,N'-bis((1,2,3,4,4a,9,10,10a-octahydro-1,4a-
dimethyl-7-(1-methyle thyl)-1-
phenanthrenyl)methyl)-1,2-ethanediamine (2:1)
CAS REGISTRY NUMBER : 3344-16-9
LAST UPDATED : 199712
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C42-H64-N2.2C16-H18-N2-O4-S
MOLECULAR WEIGHT : 1265.92
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Compocillin
* Hydrabamine penicillin G
* Penicillin G compd. with N,N'-bis(dehydroabietyl)ethylenediamine (2:1)
* Penicillin G hydrabamine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC)
V.1-12, 1951-62. For publisher information, see CLMEA3.
Volume(issue)/page/year: 5,315,1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher
information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : >1254 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher
information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher
information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955
TYPE OF TEST : LD - Lethal dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher
information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955
*** END OF RECORD ***
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