*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : XV0700000
CHEMICAL NAME : p-Tolunitrile
CAS REGISTRY NUMBER : 104-85-8
LAST UPDATED : 199707
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C8-H7-N
MOLECULAR WEIGHT : 117.16
WISWESSER LINE NOTATION : NCR D1
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* Benzonitrile, 4-methyl-
* p-Cyanotoluene
* 4-Cyanotoluene
* p-Methylbenzonitrile
* 4-Methylbenzonitrile
* 4-Methylcyanobenzene
* Nitril kyseliny p-toluylove
* p-Toluenenitrile
* 4-Toluenkarbonitril
* p-Toluic nitrile
* p-Tolunitril
* 4-Tolunitrile
* p-Toluonitrile
* p-Tolylnitrile
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,904,1986
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Mild
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,904,1986
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. (Darmstadt, Fed.
Rep. Ger.) V.1-25, 1951-75. Volume(issue)/page/year: 19,225,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZAARAM Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. (Darmstadt, Fed.
Rep. Ger.) V.1-25, 1951-75. Volume(issue)/page/year: 19,225,1969
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1080 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Lungs, Thorax, or Respiration - dyspnea
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 5,161,1899
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
m-Toluidine, 4-(octyloxy)-alpha-(p-tolylsulfonyl)-
| 5819-78-3 |
m-Toluidine, N-(2-oxazolin-2-yl)-
| 65536-43-8 |
o-Toluidine, N-(2-oxazolin-2-yl)-
| 23417-34-7 |
o-Toluidine,N-(2-oxazolin-2-yl)-alpha,alpha,alpha-trifluoro-
| 33588-19-1 |
o-Toluidine, 4,4'-pentamethylenedioxydi-,dihydrochloride
| 110194-72-4 |
p-Toluidine, alpha-phenyl-, hydrochloride
| 6317-57-3 |
p-Toluidine, N-phenylpropyl-
| 63980-34-7 |
p-Toluidine, alpha-(phenylthio)-
| 13738-70-0 |
Thorium(IV) nitrate, mixed with trisodium citrate
| 63870-17-7 |
m-Toluidine, N-phenyl-alpha,alpha,alpha-trifluoro-
| 101-23-5 |
m-Toluidine, 4-(m-tolylazo)-
| 3398-09-2 |
m-Toluidine, 4-(p-tolylazo)-
| 3963-79-9 |
o-Toluidine, 4-(m-tolylazo)-
| 4829-62-3 |
o-Toluidine, 4-(o-tolylazo)-
| 97-56-3 |
o-Toluidine, 4-(p-tolylazo)-
| 63980-18-7 |
p-Toluidine, 2-(o-tolylazo)-
| 63980-19-8 |
p-Toluidine, alpha-(p-tolylthio)-
| 54306-13-7 |
m-Toluidine, alpha,alpha,alpha-trifluoro-
| 98-16-8 |
p-Toluidine, alpha,alpha,alpha-trifluoro-
| 455-14-1 |
Thioxanthene-2-sulfonamide,N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-
| 5591-45-7 |
Thorium oxide
| 1314-20-1 |
p-Toluidine,alpha,alpha,alpha-trifluoro-2,6-dinitro-N,N-dipropyl-
| 1582-09-8 |
m-Toluidine, alpha,alpha,alpha-trifluoro-,hydrochloride
| 2646-97-1 |
m-Toluidine, 2,4,6-trinitro-
| 22603-58-3 |
m-Tolunitrile
| 620-22-4 |
o-Tolunitrile
| 529-19-1 |
p-Tolunitrile
| 104-85-8 |
o-Tolunitrile, 4-(bis(2-chloroethyl)amino)-
| 73940-94-0 |
p-Tolunitrile, alpha-(2-bornylamino)-, hydrobromide,endo-(+-)-
| 22243-56-7 |
o-Tolunitrile, alpha-chloro-
| 612-13-5 |
o-Tolunitrile, alpha-cyano-
| 3759-28-2 |
Thorium sodium citrate
| 73909-14-5 |
m-Tolunitrile, alpha-((2-(decylamino)ethyl)dithio)-,monohydrochloride
| 13116-80-8 |
p-Tolunitrile, alpha-((2-(decylamino)ethyl)dithio)-,monohydrochloride
| 13116-79-5 |
p-Tolunitrile,alpha,alpha'-(hexamethylenedinitrilo)di-
| 73940-95-1 |
m-Tolunitrile, alpha-(methylnitrosamino)-
| 98736-49-3 |
p-Tolunitrile, alpha-(4-morpholinyl)-
| 37812-51-4 |
p-Toluoyl chloride
| 874-60-2 |
p-Tolyloxy,2,6-di-tert-butyl-alpha-(3,5-di-tert-butyl-4-oxo-2,5-cyclohexadien-1-ylide ne)-
| 2370-18-5 |
Tolypanthus involucratus (Roxb.) Bl., extractSUBSTANCE DEFINITION :Plant belonging to the family LoranthaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 2370-18-5 |
Tolypomycin RB
| 102489-35-0 |
Tomastachin
| 102489-35-0 |
Th-R
| 79469-19-5 |
Tomatine
| 17406-45-0 |
alpha-Tomatine, hydrochloride
| 17605-83-3 |
Tongmai Yangxin Oral Liquid
| 17605-83-3 |
Tongxuanlifei granule
| 17605-83-3 |
Tonka absolute
| 8046-22-8 |
Toona serrata (royle) Roem., extract excluding rootsSUBSTANCE DEFINITION :Plant belonging to the family MeliaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 26,883,1988
| 8046-22-8 |
Toona serrata (royle) Roem., stem bark extractSUBSTANCE DEFINITION :Plant belonging to the family MeliaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
| 8046-22-8 |
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