*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : XW1050000
CHEMICAL NAME : Tomatine
CAS REGISTRY NUMBER : 17406-45-0
BEILSTEIN REFERENCE NO. : 0078250
REFERENCE : 4-27-00-01954 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C50-H83-N-O21
MOLECULAR WEIGHT : 1034.34
COMPOUND DESCRIPTOR : Mutagen
Natural Product
SYNONYMS/TRADE NAMES :
* A''-Tomatidine
* Lycopersicin
* Tomatidine, glycoside
* Tomatin
* alpha-Tomatine
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 17,61,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SZAPAC Schweizerische Zietschrift fuer Allgemeine Pathologie und
Bakteriologie. (White Plains, NY) V.1-3, 1938-40; V.13-22, 1950-59. For
publisher information, see ECEBDI. Volume(issue)/page/year: 22,557,1959
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca
Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 8(2),218,1982
** MUTATION DATA **
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Microorganism - not otherwise specified
DOSE/DURATION : 25 ppm
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 17,61,1979
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Microorganism - not otherwise specified
DOSE/DURATION : 25 ppm
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 17,61,1979
*** END OF RECORD ***
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