*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : YS9868000
CHEMICAL NAME : Urea, 1,3-dimethyl-
CAS REGISTRY NUMBER : 96-31-1
BEILSTEIN REFERENCE NO. : 1740672
REFERENCE : 4-04-00-00207 (Beilstein Handbook Reference)
LAST UPDATED : 199710
DATA ITEMS CITED : 10
MOLECULAR FORMULA : C3-H8-N2-O
MOLECULAR WEIGHT : 88.13
WISWESSER LINE NOTATION : 1MVM1
COMPOUND DESCRIPTOR : Mutagen
Reproductive Effector
SYNONYMS/TRADE NAMES :
* N,N'-Dimethylharnstoff
* N,N'-Dimethylurea
* sym-Dimethylurea
* 1,3-Dimethylurea
* Symmetric dimethylurea
* Urea, N,N'-dimethyl-
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag,
Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
Volume(issue)/page/year: 19,1073,1969
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 4962 mg/kg
TOXIC EFFECTS :
Behavioral - tremor
Lungs, Thorax, or Respiration - cyanosis
Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 54,188,1935
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 2 gm/kg
SEX/DURATION : female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 23,335,1981
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE : 2 gm/kg
SEX/DURATION : female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Specific Developmental Abnormalities - craniofacial
(including nose and tongue)
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 23,335,1981
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE : 2 gm/kg
SEX/DURATION : female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 23,335,1981
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Protozoa - Chlamydomonas reinhardi
DOSE/DURATION : 400 mmol/L
REFERENCE :
FOMIAZ Folia Microbiologica (Prague). (Academia, Vodickova 40, 112 29
Prague 1, Czechoslavakia) V.4- 1959- Volume(issue)/page/year:
20,452,1975
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Human Lymphocyte
DOSE/DURATION : 40 mmol/L
REFERENCE :
PNASA6 Proceedings of the National Academy of Sciences of the United States
of America. (National Academy of Sciences, Printing & Pub. Office, 2101
Constitution Ave., Washington, DC 20418) V.1- 1915-
Volume(issue)/page/year: 79,1171,1982
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0293-8714
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
|
Uridine, 2'-deoxy-, 5'-(dihydrogen phosphate)
| 964-26-1 |
|
Urea, 1,1-dimethyl-
| 598-94-7 |
|
Uridine, 2'-deoxy-5-ethyl-
| 15176-29-1 |
|
Uridine, 2'-deoxy-5-ethynyl-
| 61135-33-9 |
|
Uridine, 2'-deoxy-5-fluoro-
| 50-91-9 |
|
Uridine, 5'-deoxy-5-fluoro-
| 3094-09-5 |
|
Uridine, 2'-deoxy-5-fluoro-3'-O-(phenylmethyl)-
| 95969-44-1 |
|
Uridine, 2'-deoxy-5-fluoro-3'-O-(phenylmethyl)-,5'-acetate
| 103766-68-3 |
|
Uridine, 2'-deoxy-5-(hydroxymethyl)-
| 5116-24-5 |
|
Uridine, 2'-deoxy-5-iodo-
| 54-42-2 |
|
Uridine, 2'-deoxy-5-(2-iodovinyl)-, (E)-
| 69304-48-9 |
|
Uridine, 2'-deoxy-5-mercapto-
| 7085-54-3 |
|
Urea, 1,3-dimethyl-
| 96-31-1 |
|
Uridine, 2'-deoxy-5-methoxymethyl-
| 5116-22-3 |
|
Uridine, 2'-deoxy-5-nitro-, 5'-dihydrogen phosphate
| 5116-22-3 |
|
Uridine, 2'-deoxy-5-(1-propenyl)-, (E)-
| 66270-29-9 |
|
Uridine, 2'-deoxy-5-(3,3,3-trifluoro-1-propenyl)-,(E)-
| 69819-96-1 |
|
Uridine, 2'-deoxy-5-vinyl-
| 55520-67-7 |
|
Uridine, 5'-dihydrogen phosphate, disodium salt
| 3387-36-8 |
|
Uridine, 5-fluoro-
| 316-46-1 |
|
Uridine, 5-fluoro-2',3'-O-(1-methylethylidene)-
| 2797-17-3 |
|
Uridine, 5-((formyloxy)methyl)-
| 129051-71-4 |
|
Uridine, 4-hydrazone
| 57294-74-3 |
|
Urea, 1-(N,N-dimethylalanyl)-3-(p-ethoxyphenyl)-
| 4046-47-3 |
|
Uridine, 4-oxime
| 3258-02-4 |
|
Uridine, 5'-(tetrahydrogen triphosphate)
| 63-39-8 |
|
5'-Uridylic acid
| 58-97-9 |
|
5'-Uridylic acid, sodium salt
| 7545-48-4 |
|
UrocalumSUBSTANCE DEFINITION :Extracted from C. salicina Oerst.REFERENCE :NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,Japan) Volume(issue)/page/year: 6,96,1982
| 7545-48-4 |
|
Urokrein
| 7545-48-4 |
|
Ursa-9(11),12-diene-3,28-diol, bis(hydrogen1,2-benzendicarboxylate), disodium salt, (3-beta)-
| 146029-91-6 |
|
Urs-12-ene-23,28-dioic acid, 2,3-bis(acetyloxy)-,(2-alpha,3-beta,4-beta,20-beta)-
| 79679-46-2 |
|
Urs-12-ene-27,28-dioic acid, 3-beta-hydroxy-
| 465-74-7 |
|
Urs-12-en-28-oic acid, 3-beta-hydroxy-,2-(dimethylamino)ethyl ester, hydrochloride
| 465-74-7 |
|
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