RTECS NUMBER : DH2455000
CHEMICAL NAME : Benzoic acid, p-hydroxy-, methyl ester, sodium deriv.
CAS REGISTRY NUMBER : 5026-62-0
LAST UPDATED : 199712
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C8-H7-O3.Na
MOLECULAR WEIGHT : 174.14
WISWESSER LINE NOTATION : OR DVO1 &-NA-
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Bonomold OMNa
* Methyl p-hydroxybenzoate, sodium salt
* Preserval MS
* Sodium 4-carbomethoxyphenolate
* Sodium, (p-carboxyphenoxy)-, methyl ester
* Sodium p-methoxycarbonylphenoxide
* Sodium methyl p-hydroxybenzoate
* Sodium methylparaben
* Solparol
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 45,260,1956
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 760 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Behavioral - somnolence (general depressed activity)
Behavioral - ataxia
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 45,260,1956
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 170 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAPMA8 Journal of the American Pharmaceutical Association, Scientific
Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see
JPMSAE. Volume(issue)/page/year: 45,260,1956
*** END OF RECORD ***
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