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MSDS  : Coumarin, 3-chloro-7-hydroxy-4-methyl-, bis(2-chloroethyl) phosphate
CAS  : 321-55-1
SYNONYMS  : * O,O-Bis(2-chloroethyl) O-(3-chloro-4-methyl-7-coumarinyl) phosphate * 3-Chloro-7-hydroxy-4-methylcoumarin bis(2-chloroethyl)phosphate * 3-Chloro-4-methyl-umbelliferone bis(2-chloroethyl)phosphate * Di-(2-chloroethyl)-3-chloro-4-methyl-7-coumarinyl phosphate * Di-(2-chloroethyl) 3-chloro-4-methylcoumarin-7-yl phosphate * O,O-Di(2-chloroethyl)-O-(3-chloro-4-methylcoumarin-7-yl)phosphate * Ethanol, 2-chloro-, hydrogen phosphate, ester with 3-chloro-7-hydroxy-4-methylcoumarin * Ethanol, 2-chloro-, phosphate diester, ester with 3-chloro-7-hydroxy-4-methylcoumarin * Eustidil * Galloxon * Galoxane * Galoxone * 96H60 * Haloxon * Helmirane * Helmiron * Helmirone * Loxon * Luxon * LXON
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : GN5250000
CHEMICAL NAME : Coumarin, 3-chloro-7-hydroxy-4-methyl-,
bis(2-chloroethyl) phosphate
CAS REGISTRY NUMBER : 321-55-1
BEILSTEIN REFERENCE NO. : 1271357
LAST UPDATED : 199612
DATA ITEMS CITED : 8
MOLECULAR FORMULA : C14-H14-Cl3-O6-P
MOLECULAR WEIGHT : 415.60
WISWESSER LINE NOTATION : T66 BOVJ DG E1 IOPO&O2GO2G
COMPOUND DESCRIPTOR : Agricultural Chemical
Mutagen
SYNONYMS/TRADE NAMES :
* O,O-Bis(2-chloroethyl) O-(3-chloro-4-methyl-7-coumarinyl) phosphate
* 3-Chloro-7-hydroxy-4-methylcoumarin bis(2-chloroethyl)phosphate
* 3-Chloro-4-methyl-umbelliferone bis(2-chloroethyl)phosphate
* Di-(2-chloroethyl)-3-chloro-4-methyl-7-coumarinyl phosphate
* Di-(2-chloroethyl) 3-chloro-4-methylcoumarin-7-yl phosphate
* O,O-Di(2-chloroethyl)-O-(3-chloro-4-methylcoumarin-7-yl)phosphate
* Ethanol, 2-chloro-, hydrogen phosphate, ester with
3-chloro-7-hydroxy-4-methylcoumarin
* Ethanol, 2-chloro-, phosphate diester, ester with
3-chloro-7-hydroxy-4-methylcoumarin
* Eustidil
* Galloxon
* Galoxane
* Galoxone
* 96H60
* Haloxon
* Helmirane
* Helmiron
* Helmirone
* Loxon
* Luxon
* LXON

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research.
(Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way,
Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 17,108,1973

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >6 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71.
Discontinued. Volume(issue)/page/year: 9,119,1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : >7 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
16,1183,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Bird - chicken
DOSE/DURATION : 800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year:
16,1183,1967

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - domestic
DOSE/DURATION : 763 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Behavioral - food intake (animal)
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
AJVRAH American Journal of Veterinary Research. (American Veterinary
Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.1- 1940-
Volume(issue)/page/year: 41,1857,1980

** MUTATION DATA **

TYPE OF TEST : DNA inhibition
TEST SYSTEM : Human Cells - not otherwise specified
DOSE/DURATION : 10 mg/L
REFERENCE :
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub.,
1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
Volume(issue)/page/year: 10,143,1982

*** REVIEWS ***

TOXICOLOGY REVIEW
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44
Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year:
46,1,1973

TOXICOLOGY REVIEW
PMDCAY Progress in Medical Chemistry. (Elsevier Science Pub. Co., Inc., 52
Vanderbilt Ave., New York, NY 10017) V.1- 1961- Volume(issue)/page/year:
10,85,1974


*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Coumarin, 3-amino-4-diethylamino- 101468-13-7
Coumarin, 3-amino-4-dipropylamino- 69405-47-6
Coumarin, 6-amino-, hydrochloride 63989-79-7
Coumarin, 7-amino-4-hydroxy-3-sulfanilamido-,monosodium salt 13711-97-2
Coumarin, 3-amino-4-methylamino- 59288-10-7
Coumarin, 3-amino-4-(4-methyl-1-piperazinyl)- 59288-17-4
Coumarin, 3-amino-4-morpholino- 59288-16-3
Clinoptilolite 12173-10-3
Coumarin, 6-amino-3-(morpholinocarbonyl)- 18144-57-5
Coumarin, 4-amino-3-nitro- 38464-21-0
Coumarin, 3-amino-4-(4-phenyl-1-piperazinyl)- 69405-48-7
Coumarin, 3-amino-4-piperidino- 38464-24-3
Coumarin, 6-amino-3-(piperidinocarbonyl)- 18144-56-4
Coumarin, 6-amino-3-((piperidinocarbonyl)methyl)- 18144-59-7
Coumarin, 6-amino-3-(4-pyridyl)- 3390-71-4
Coumarin, 3-amino-4-(1-pyrrolidinyl)- 59288-15-2
Coumarin, 6-amino-3-(1-pyrrolidinylcarbonyl)- 18144-55-3
Coumarin, 6-amino-3-((1-pyrrolidinylcarbonyl)methyl)- 18144-58-6
Citric acid, trisodium salt, compd. with potassiumcitrate and citric acid, (2:2:1) 55049-48-4
Clinoptilolite (AlNaH16(SiO4)5.4H2O) 67240-23-7
Coumarin, 4-anilino-3-nitro- 50527-30-5
Coumarin, 3-benzoyl- 1846-74-8
Coumarin, 3-(2-benzoylethyl)-4-hydroxy- 6431-16-9
Coumarin, 4-benzylamino-3-nitro- 50527-29-2
Coumarin,3-(3-(4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxy- 56073-07-5
Coumarin,8-((bis(2-hydroxyethyl)amino)methyl)-6,7-dihydroxy-4-methyl-, hydrochloride 1039-82-3
Coumarin, 5,7-bis(2-morpholinoethoxy)-4-methyl-,hydrochloride 1039-82-3
Coumarin,3-(3-(4'-bromo-1,1'-biphenyl-4-yl)-3-hydroxy-1-phenylpropyl)-4-hydroxy- 28772-56-7
Coumarin,3-(3-(4'-bromo-1,1'-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl)-4-hydrox y- 56073-10-0
Coumarin,6-bromo-4-hydroxy-3-((m-hydroxyphenyl)carbamoyl)- 19225-15-1
Clinoptilolite (Na(AlSi5O12).xH2O) 12271-42-0
Coumarin, 6-bromo-3-(2-pyridyl)- 958-58-7
Coumarin, 6-bromo-3-(4-pyridyl)- 67210-65-5
Coumarin, 3-butyl- 66898-41-7
Coumarin, 4-butylamino-3-nitro- 50527-27-0
Coumarin, 8-tert-butyl-4,6-dimethyl- 17874-34-9
Coumarin, 6-chloro- 2051-59-4
Coumarin, 3,3'-(o-chlorobenzylidene)bis(4-hydroxy- 4322-58-1
Coumarin, 3,3'-(p-chlorobenzylidene)bis(4-hydroxy- 4322-59-2
Coumarin, 3-(p-chloro-alpha-ethylbenzyl)-4-hydroxy- 2728-02-1
Coumarin, 3-chloro-7-hydroxy-4-methyl-,bis(4-chlorobutyl)phosphate 14745-61-0
Clitoria ternatea Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family FabaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 14745-61-0
Coumarin, 3-chloro-7-hydroxy-4-methyl-,bis(2-chloroethyl) phosphate 321-55-1
Coumarin, 3-chloro-7-hydroxy-4-methyl-,bis(2-chloropropyl)phosphate 4482-85-3
Coumarin, 3-chloro-7-hydroxy-4-methyl-,bis(3-chloropropyl) phosphate 4467-21-4
Coumarin, 3-chloro-7-hydroxy-4-methyl-,bis(2,3-dichloropropyl)phosphate 14663-70-8
Coumarin, 3-chloro-7-hydroxy-4-methyl-, dibutylphosphate 14663-66-2
Coumarin, 3-chloro-7-hydroxy-4-methyl-, diethylphosphate 321-54-0
Coumarin, 3-chloro-7-hydroxy-4-methyl-, dipropylphosphate 14663-67-3
Coumarin, 3-chloro-7-hydroxy-4-methyl-, O-ester withO,O-diethyl phosphorothioate 56-72-4

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