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MSDS  : Cyanogen chloride
CAS  : 506-77-4
SYNONYMS  : * Chlorcyan * Chlorine cyanide * Chlorocyan * Chlorocyanide * Chlorocyanogen * Chlorure de cyanogene * Cyanogen chloride * RCRA waste number P033
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : GT2275000
CHEMICAL NAME : Cyanogen chloride
CAS REGISTRY NUMBER : 506-77-4
BEILSTEIN REFERENCE NO. : 0969190
REFERENCE : 4-03-00-00090 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 29
MOLECULAR FORMULA : C-Cl-N
MOLECULAR WEIGHT : 61.47
WISWESSER LINE NOTATION : G CN
COMPOUND DESCRIPTOR : Agricultural Chemical
Tumorigen
Human
SYNONYMS/TRADE NAMES :
* Chlorcyan
* Chlorine cyanide
* Chlorocyan
* Chlorocyanide
* Chlorocyanogen
* Chlorure de cyanogene
* Cyanogen chloride
* RCRA waste number P033

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Human
DOSE/DURATION : 10 mg/m3
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation
Sense Organs and Special Senses (Eye) - conjunctive irritation
Lungs, Thorax, or Respiration - chronic pulmonary edema
REFERENCE :
WHOTAC World Health Organization, Technical Report Series. (WHO, 1211
Geneva, 27, Switzerland) No.1- 1950- Volume(issue)/page/year: -,31,1970

TYPE OF TEST : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Human - man
DOSE/DURATION : 2 gm/m3
TOXIC EFFECTS :
Skin and Appendages - primary irritation (after topical exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB158-508

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1341,1935

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 3300 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB158-508

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : 6 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB158-508

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1341,1935

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 3150 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB158-508

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Bird - pigeon
DOSE/DURATION : 8700 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
Ger. Dem. Rep.) Volume(issue)/page/year: 4,1341,1935

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - domestic
DOSE/DURATION : 2970 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB158-508

*** REVIEWS ***

ACGIH TLV-CL 0.75 mg/m3 (0.3 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-AUSTRALIA:TWA 0.3 ppm (0.6 mg/m3) JAN 1993

OEL-BELGIUM:STEL 0.3 ppm (0.75 mg/m3) JAN 1993

OEL-DENMARK:TWA 0.1 ppm (0.3 mg/m3) JAN 1993

OEL-FINLAND:STEL 0.1 ppm (0.3 mg/m3);Skin JAN 1993

OEL-FRANCE:STEL 0.3 ppm (0.6 mg/m3) JAN 1993

OEL-THE NETHERLANDS:TWA 0.3 ppm (0.6 mg/m3) JAN 1993

OEL-SWEDEN:TWA 0.1 ppm (0.3 mg/m3);STEL 0.3 ppm (0.8 mg/m3) JAN 1993

OEL-SWITZERLAND:TWA 0.3 ppm (0.8 mg/m3) JAN 1993

OEL-UNITED KINGDOM:TWA 0.3 ppm (0.6 mg/m3);STEL 0.3 ppm JAN 1993

OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV

OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO CYANOGEN CHLORIDE-air:CL 0.3 ppm
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 84337
No. of Facilities: 34 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 134 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 84337
No. of Facilities: 4 (estimated)
No. of Industries: 1
No. of Occupations: 16
No. of Employees: 1391 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9033

On EPA IRIS database

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

NTP Carcinogenesis studies; selected, October 1997


*** END OF RECORD ***
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