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MSDS  : 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-, (3R- (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,10-alpha,12-b eta,12aR*))-, mixt. with (3R-(3- alpha,5a-beta,6-beta,8a-beta,9-alpha,10-beta,12-beta, 12aR*))-10-ethoxydeca hydro-3,6,9- trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxe pin
CAS  : 123492-25-1
SYNONYMS  : * alpha/beta-Arteether * 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin, 10-ethoxydecahydro-3,6,9-trimethyl-
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : KD4165500
CHEMICAL NAME : 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin,
10-ethoxydecahydro-3,6,9-trimethyl-, (3R-
(3-alpha,5a-beta,6-beta,8a-beta,9-alpha,10-alpha,12-b
eta,12aR*))-, mixt. with (3R-(3-
alpha,5a-beta,6-beta,8a-beta,9-alpha,10-beta,12-beta,
12aR*))-10-ethoxydeca hydro-3,6,9-
trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxe
pin
CAS REGISTRY NUMBER : 123492-25-1
LAST UPDATED : 199310
DATA ITEMS CITED : 1
MOLECULAR FORMULA : C17-H28-O5.C17-H28-O5
MOLECULAR WEIGHT : 624.90
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* alpha/beta-Arteether
* 3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin,
10-ethoxydecahydro-3,6,9-trimethyl-

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : >1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland
Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year:
27,297,1989

*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
1H,3H-4,7-Epoxy-3a,7a-propanoisobenzofuran-1,3-dione,tetrahydro-, (3a-alpha,4-beta,7-beta,7a-alpha)- 115966-98-8
3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin,decahydro-10-methoxy-3,6,9-trimethyl-,(3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR)-, (+)- 71963-77-4
3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin,decahydro-10-methoxy-3,6,9-trimethyl-,(3R-(3-alpha,5a-beta,6-beta,8a-alpha,9-alpha,10-beta,12-beta,12aR*))- 80286-56-2
3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin-10-alpha-ol, decahydro-3,6,9-trimethyl-, propionate (ester) 56973-26-3
1,5-Epoxy-1H-(1,4)oxazocino(4,3-a)benzimidazole,3,4,5,6-tetrahydro-1-phenyl- 76099-34-8
3,12-Epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin,10-ethoxydecahydro-3,6,9-trimethyl-, (3R-(3-alpha,5a-beta,6-beta,8a-beta,9-alpha,10-alpha,12-beta,12aR*))-, mixt. with (3R-(3-alpha,5a-beta,6-beta,8a-beta,9-alpha,10-beta,12-beta,12aR*))-10-ethoxydeca hydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano(4,3-j)-1,2-benzodioxepin 123492-25-1
3,12-Epoxy-12H-pyranol(4,3-j)-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, (3-alpha,5a-beta,6-beta,8a-beta,9-alpha,12-beta,12aR*)-(+)- 63968-64-9
6,9-Epoxy-6H,8H-pyrido(3',2'4,5)imidazo(2,1-c)oxazepine, 9,10-dihydro-6-phenyl- 76099-26-8
6,9-Epoxy-6H,8H-pyrido(4',3'4,5)imidazo(2,1-c)oxazepine, 9,10-dihydro-6-phenyl- 76099-28-0
7,10-Epoxy-6H,10H-pyrido(3',44,5)imidazo(2,1-c)(1,4)oxazepine, 7,8-dihydro-10-phenyl- 76099-29-1
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-te trone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-8-ethyl-3-( 2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl -,(3S-(3R*(E(1S*,3S*,4S*)),4S*,19S*,26aR*))- 104987-12-4
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-te trone,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy -3-(2-(4-hydroxy-3-methoxycyclohexyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-,(3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR *))- 104987-11-3
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-te trone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hyd roxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,8,10,12,18-pentameth yl-,(3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR *))- 104987-09-9
15,19-Epoxy-1H,3H-pyrrolo(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H)-te trone, 5,6,8,11,12,13,14,15,16,17,18,19,23,24,25,25a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hyd roxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl -8-(2-propenyl)-,(3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR *))- 104987-10-2
Epoxy resin 618 104987-10-2
2,6-Epoxyoxireno(f)isobenzofuran-3,5-dione,hexahydro-, (1a-alpha,2-beta,2a-alpha,5a-alpha,6-beta,6a-alpha)- 82660-86-4
Epoxy resin (dimethylhydantoin deriv.) 82660-86-4
Epoxy resin erl-2795 25068-38-6
Epoxy resin err-0100 57608-57-8
Epoxy resin err-0901 57608-57-8
1,4-Epoxy-1H,3H-(1,4)thiazepino(4,3-a)benzimidazole,4,5-dihydro-1-phenyl- 76099-30-4
12,16-Epoxy-5H,12H-6,11b,16a-triazadibenzo(b,h)cyclonona(jkl)cyclopent(e)- as-indacen-5-one,6,7,13,14,15,16-hexahydro-13-methoxy-12-methyl-14-(methylamino)-, hydrochloride,(12-alpha,13-beta,14-beta,16-alpha)-(+)- 76099-30-4
Equilenin, benzoate 604-58-0
Equilin, benzoate 6030-80-4
Equinatoxin 54578-46-0
Equinatoxin ISUBSTANCE DEFINITION :Lethal and hemolytic toxin from the sea anemone Actinia equina L.REFERENCE :TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,UK) V.1- 1962- 54578-46-0
9,4-(Epoxypentadeca(1,11,13)trienimino)-1H-benzofuro(5,4-g)indole-3-carbox ylic acid, 9,10-dihydro-10,26-dioxo-5,6,16,18,20-pentahydroxy-7,9,15,17,19,21,25-heptameth yl-14-methoxy-, methyl ester,16-acetate 102366-76-7
Equinatoxin IIISUBSTANCE DEFINITION :Lethal and hemolytic toxin from the sea anemone Actinia equina L.REFERENCE :TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,UK) V.1- 1962- Volume(issue)/page/year: 26,441,1988 102366-76-7
Equisetin 57749-43-6
Equisetum diffusum D. Don, extractSUBSTANCE DEFINITION :Plant belonging to the family EquisetaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 12,512,1974 57749-43-6
Erabutoxin 59536-69-5
Erabutoxin A 11094-61-4
Erabutoxin A, 26-L-histidine- 9083-23-2
Eradicane 51990-04-6
Eragrostis diarrhena (schult. f.) Steud., extractSUBSTANCE DEFINITION :Plant belonging to the family PoaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 51990-04-6
Eragrostis tremula Hochst., extractSUBSTANCE DEFINITION :Plant belonging to the family GramineaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 51990-04-6
Eragrostis unioloides (retz.) Nees ex Steud., extractexcluding rootsSUBSTANCE DEFINITION :Plant belonging to the family PoaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,487,1984 51990-04-6
9,4-(Epoxypentadeca(1,11,13)trienimino)-1H-benzofuro(5,4-g)indole-3-carbox ylic acid, 9,10-dihydro-10,26-dioxo-5,6,16,18,20-pentahydroxy-14-methoxy-2,7,9,15,17,19,21 ,25-octamethyl-, methyl ester,16-acetate 51990-04-6
Eranthemum capense Linn., extractSUBSTANCE DEFINITION :Plant belonging to the family AcanthaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-Volume(issue)/page/year: 22,487,1984 51990-04-6
Eranthemum roseum R. Br., root and stem extractSUBSTANCE DEFINITION :Plant belonging to the family AcanthaceaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 51990-04-6
Erbium chloride 10138-41-7
Erbium citrate 3088-54-8
Erbium edetate 12611-40-4
Erbium(III) nitrate (13) 10168-80-6
Erbium(III) nitrate, hexahydrate (136) 13476-05-6
Erbium trioxide 12061-16-4
Erechtites valerianaefolia DC., extractSUBSTANCE DEFINITION :Plant belonging to the family CompositaeREFERENCE :IJEBA6 Indian Journal of Experimental Biology. (Publications & InformationDirectorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- 12061-16-4
Eremomycin 110865-90-2
9,4-(Epoxypentadeca(1,11,13)trienimino)-1H-benzofuro(5,4-g)indole-10,26(9H )-dione, 3-acetyl-5,6,16,18,20-pentahydroxy-14-methoxy-1,2,7,9,15,17,19,21,25-nonamethyl-, 16-acetate 21240-38-0
Eremomycin, sulfateSUBSTANCE DEFINITION :Extracted from Actinomycate INA-238REFERENCE :AMBIEH Antibiotiki i Meditsinskaya Biotekhnologiya. Antibiotics and MedicalBiotechnology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.30-V.32,1985-1987 Volume(issue)/page/year: 32,910,1987 21240-38-0

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