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MSDS  : D-Gluconic acid, compd. with N,N''-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13- tetraazatetradecane diimidamide (2:1)
CAS  : 18472-51-0
SYNONYMS  : * Abacil * Arlacide G * Bacticlens * Biguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-, digluconate * 1,6-Bis(5-(p-chlorophenyl)biguandino)hexane digluconate * Caswell No. 481G * Chlorhexidine digluconate * Chlorhexidine di-D-gluconate * Chlorhexidine gluconate * Chlorhexidin glukonatu * Corsodyl * Disteryl * Gluconic acid, compd. with 1,1'-hexamethylene bis(5-(p-chlorophenyl)biguanide) (2:1), D- * 1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide)digluconate * Hibiclens * Hibidil * Hibiscrub * Hibitane 5 * Orahexal * Peridex * Peridex (antiseptic) * Plac out * Plurexid * Septeal * Unisept
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : DU1950000
CHEMICAL NAME : D-Gluconic acid, compd. with
N,N''-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-
tetraazatetradecane diimidamide (2:1)
CAS REGISTRY NUMBER : 18472-51-0
OTHER CAS REGISTRY NOS. : 14007-07-9
60042-57-1
LAST UPDATED : 199706
DATA ITEMS CITED : 10
MOLECULAR FORMULA : C22-H30-Cl2-N10.2C6-H12-O7
MOLECULAR WEIGHT : 897.88
WISWESSER LINE NOTATION : GR DMYUM&MYUM&M6MYUM&MYUM&MR DG &QVYQYQYQYQ1Q 2
COMPOUND DESCRIPTOR : Drug
Mutagen
SYNONYMS/TRADE NAMES :
* Abacil
* Arlacide G
* Bacticlens
* Biguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-, digluconate
* 1,6-Bis(5-(p-chlorophenyl)biguandino)hexane digluconate
* Caswell No. 481G
* Chlorhexidine digluconate
* Chlorhexidine di-D-gluconate
* Chlorhexidine gluconate
* Chlorhexidin glukonatu
* Corsodyl
* Disteryl
* Gluconic acid, compd. with 1,1'-hexamethylene
bis(5-(p-chlorophenyl)biguanide) (2:1), D-
* 1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide)digluconate
* Hibiclens
* Hibidil
* Hibiscrub
* Hibitane 5
* Orahexal
* Peridex
* Peridex (antiseptic)
* Plac out
* Plurexid
* Septeal
* Unisept

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,255,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 3320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,255,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 24200 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,255,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,255,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,255,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 12900 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,255,1982

** MUTATION DATA **

TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 1 mg/L
REFERENCE :
ESKGA2 Eisei Kagaku. Hygienic Chemistry. (Nippon Yakugakkai, 2-12-15
Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1953-
Volume(issue)/page/year: 32,171,1986

*** U.S. STANDARDS AND REGULATIONS ***

EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X3093
No. of Facilities: 4592 (estimated)
No. of Industries: 5
No. of Occupations: 36
No. of Employees: 643404 (estimated)
No. of Female Employees: 561783 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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