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MSDS  : Gluconic acid, iron(2+) salt (21)
CAS  : 299-29-6
SYNONYMS  : * Fergon * Fergon preparations * Ferlucon * Ferronicum * Ferrous gluconate * Gluco-ferrum * Iromin * Iron gluconate * Irox (gador) * Nionate * Ray-gluciron
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : LZ5150000
CHEMICAL NAME : Gluconic acid, iron(2+) salt (2:1)
CAS REGISTRY NUMBER : 299-29-6
OTHER CAS REGISTRY NOS. : 18829-42-0
LAST UPDATED : 199701
DATA ITEMS CITED : 17
MOLECULAR FORMULA : C12-H22-Fe-O14
MOLECULAR WEIGHT : 446.19
WISWESSER LINE NOTATION : Q1YQYQYQYQVO & 2-FE-
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
Human
SYNONYMS/TRADE NAMES :
* Fergon
* Fergon preparations
* Ferlucon
* Ferronicum
* Ferrous gluconate
* Gluco-ferrum
* Iromin
* Iron gluconate
* Irox (gador)
* Nionate
* Ray-gluciron

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - child
DOSE/DURATION : 162 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
Gastrointestinal - nausea or vomiting
REFERENCE :
JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N.
Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year:
218,1179,1971

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 2237 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: UR-3490-168

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 3950 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove
Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year:
241,296,1961

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove
Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year:
241,296,1961

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 199 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AJMSA9 American Journal of the Medical Sciences. (Slack Inc., 6900 Grove
Rd., Thorofare, NJ 08086) New series: V.1- 1841- Volume(issue)/page/year:
241,296,1961

** TUMORIGENIC DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2600 mg/kg/13W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
Reproductive - Tumorigenic effects - ovarian tumors
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60,
1940-78. For publisher information, see JJIND8. Volume(issue)/page/year:
24,109,1960

*** REVIEWS ***

TOXICOLOGY REVIEW
CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher
information, see JTCTDW. Volume(issue)/page/year: 4,615,1971

*** U.S. STANDARDS AND REGULATIONS ***

MSHA STANDARD-air:TWA 1 mg(Fe)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,138,1971

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-DENMARK:TWA 1 mg(Fe)/m3 JAN 1993

OEL-FINLAND:TWA 1 mg(Fe)/m3 JAN 1993

OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JAN 1993

OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JAN 1993

OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JAN 1993

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80415
No. of Facilities: 181 (estimated)
No. of Industries: 2
No. of Occupations: 12
No. of Employees: 14676 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 80415
No. of Facilities: 454 (estimated)
No. of Industries: 4
No. of Occupations: 18
No. of Employees: 10496 (estimated)
No. of Female Employees: 3906 (estimated)

*** STATUS IN U.S. ***

EPA GENETOX PROGRAM 1988, Negative: D melanogaster Sex-linked lethal

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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