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MSDS  : Acrylonitrile, 2-(p-methoxyphenyl)-3,3-diphenyl-
CAS  : 16143-89-8
SYNONYMS  : * alpha-(p-Methoxyphenyl)-beta,beta-diphenylacrylonitrile * 2-(p-Methoxyphenyl)-3,3-diphenylacrylonitrile
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : AT6900000
CHEMICAL NAME : Acrylonitrile, 2-(p-methoxyphenyl)-3,3-diphenyl-
CAS REGISTRY NUMBER : 16143-89-8
BEILSTEIN REFERENCE NO. : 2814176
REFERENCE : 3-10-00-01337 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C22-H17-N-O
MOLECULAR WEIGHT : 311.40
WISWESSER LINE NOTATION : 1OR DYCN&UYR&R
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* alpha-(p-Methoxyphenyl)-beta,beta-diphenylacrylonitrile
* 2-(p-Methoxyphenyl)-3,3-diphenylacrylonitrile

*** HEALTH HAZARD DATA ***

** TUMORIGENIC DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 94 mg/kg/26W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
REFERENCE :
MMJJAI Mie Medical Journal. (Mie Univ. of Medicine, Tsu 514, Japan) V.3-
1952- Volume(issue)/page/year: 11,95,1961

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Parenteral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 320 mg/kg/1Y-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Blood - lymphoma, including Hodgkin's disease
Skin and Appendages - tumors
REFERENCE :
NNGZAZ Nippon Naibumpi Gakkai Zasshi. Journal of the Japan Endocrine
Society. (Nippon Naibumpi Gakkai, c/o Kyoto-Furitsu Ika Daigaku, Kojinbashi
Nishizume-Sagaru, Kamigyo-ku, Kyoto 602, Japan) V.1- 1925-
Volume(issue)/page/year: 33,53,1957

*** END OF RECORD ***
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