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MSDS  : Hypochlorous acid, sodium salt, pentahydrate
CAS  : 10022-70-5
SYNONYMS  : * Sodium hypochlorite pentahydrate
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : NH3486800
CHEMICAL NAME : Hypochlorous acid, sodium salt, pentahydrate
CAS REGISTRY NUMBER : 10022-70-5
LAST UPDATED : 199706
DATA ITEMS CITED : 10
MOLECULAR FORMULA : Cl-O.Na.5H2-O
MOLECULAR WEIGHT : 164.54
COMPOUND DESCRIPTOR : Tumorigen
Primary Irritant
SYNONYMS/TRADE NAMES :
* Sodium hypochlorite pentahydrate

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 18-4/1970

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 100 mg
REACTION SEVERITY : Moderate
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 18-4/1970

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 8910 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Olfaction) - effect, not otherwise
specified
Behavioral - somnolence (general depressed activity)
Behavioral - muscle weakness
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 18-4/1970

TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >10500 mg/m3/1H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - lacrimation
Behavioral - somnolence (general depressed activity)
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 18-4/1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : >10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 18-4/1970

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 50400 ug/kg/28D-C
TOXIC EFFECTS :
Endocrine - changes in adrenal weight
REFERENCE :
BIOFX* BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. (1810
Frontage Rd., Northbrook, IL 60062) Volume(issue)/page/year: 18-4/1970

*** REVIEWS ***

IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 52,159,1991

IARC Cancer Review:Human No Available Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 52,159,1991

IARC Cancer Review:Group 3
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 52,159,1991

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - X7253
No. of Facilities: 4 (estimated)
No. of Industries: 1
No. of Occupations: 3
No. of Employees: 979 (estimated)
No. of Female Employees: 33 (estimated)


*** END OF RECORD ***
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