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MSDS  : Hyoscyamine, (-)-
CAS  : 101-31-5
SYNONYMS  : * (-)-Atropine * Daturine * Duboisine * Hyoscyamine * (-)-Hyoscyamine * 1-Hyoscyamine * Levsin * Tropic acid, (-)-, ester with tropine * Tropine, (-)-tropate (ester)
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : NH0875000
CHEMICAL NAME : Hyoscyamine, (-)-
CAS REGISTRY NUMBER : 101-31-5
LAST UPDATED : 199701
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C17-H23-N-O3
MOLECULAR WEIGHT : 289.41
WISWESSER LINE NOTATION : T56 A ANTJ A1 GOVYR&1Q -L
COMPOUND DESCRIPTOR : Human
Natural Product
SYNONYMS/TRADE NAMES :
* (-)-Atropine
* Daturine
* Duboisine
* Hyoscyamine
* (-)-Hyoscyamine
* 1-Hyoscyamine
* Levsin
* Tropic acid, (-)-, ester with tropine
* Tropine, (-)-tropate (ester)

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Human - man
DOSE/DURATION : 1471 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M.,
Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 95 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK)
V.1-33, 1946-68. For publisher information, see BJPCBM.
Volume(issue)/page/year: 24,138,1965

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - A1029
No. of Facilities: 68 (estimated)
No. of Industries: 1
No. of Occupations: 6
No. of Employees: 2770 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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NAMECAS
Hyoscyamine, (-)- 101-31-5
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