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MSDS  : Indole, 3-((dimethylamino)methyl)-
CAS  : 87-52-5
SYNONYMS  : * beta-Dimethylaminomethylindole * 3-(Dimethylaminomethyl)indole * Donaxin * Donaxine * Gramin * Gramine * 1H-Indole-3-methanamine, N,N-dimethyl-
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : NL7525000
CHEMICAL NAME : Indole, 3-((dimethylamino)methyl)-
CAS REGISTRY NUMBER : 87-52-5
LAST UPDATED : 199712
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C11-H14-N2
MOLECULAR WEIGHT : 174.27
WISWESSER LINE NOTATION : T56 BMJ D1N1&1
COMPOUND DESCRIPTOR : Agricultural Chemical
Drug
SYNONYMS/TRADE NAMES :
* beta-Dimethylaminomethylindole
* 3-(Dimethylaminomethyl)indole
* Donaxin
* Donaxine
* Gramin
* Gramine
* 1H-Indole-3-methanamine, N,N-dimethyl-

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council,
Chemical-Biological Coordination Center, Review. (Washington, DC)
Volume(issue)/page/year: 5,11,1953

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 122 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For
publisher information, see PSCHDL. Volume(issue)/page/year: 16,385,1970

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 46 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
Behavioral - excitement
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams &
Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
Volume(issue)/page/year: 105,130,1952

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 127 gm/kg/3W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in both tubules and glomeruli
Endocrine - changes in spleen weight
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - phosphatases
REFERENCE :
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
Limerick, Ireland) V.1- 1973- Volume(issue)/page/year: 18,125,1980

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY


*** END OF RECORD ***
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NAMECAS
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Indole, 3-(2-((3-amino-4-pyridyl)amino)ethyl)-,dihydrochloride 18527-61-2
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Indole, 3-(2-(diisobutylamino)ethyl)-,monohydrochloride 63938-64-7
Indole, 3-(2-(diisopropylamino)ethyl)-,monohydrochloride 67292-67-5
Indole,5,6-dimethoxy-2-methyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)- 153-87-7
Indole,5,6-dimethoxy-2-methyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)-, hydrochloride 40523-01-1
1H-Indole,2-(2,4-dimethoxyphenyl)-3-((1H-tetrazol-5-ylmethyl)thio)- 66355-04-2
Indole, 2,3-dimethyl- 91-55-4
Indole, 5-(dimethylamino)- 6843-23-8
Indole, 3-(dimethylaminoacetyl)- 30256-72-5
3H-Indole, 3-(p-dimethylamino)benzylidene- 74038-99-6
Indole, 5-amino-3-(1-pyrrolidinylmethyl)- 3414-75-3
Indole, 3-(4-(dimethylamino)butyl)-, hydrochloride 74039-00-2
Indole, 3-(3-(dimethylamino)-2-butyl)-5-methylthio- 5564-16-9
Indole, 3-(4-(dimethylamino)butyl)-1-phenyl- 102552-17-0
Indole, 5-dimethylamino-3-(2-(dimethylamino)ethyl)- 6843-22-7
Indole, 5-(dimethylamino)-3-((dimethylamino)methyl)- 6843-25-0
Indole, 3-(2-(dimethylamino)ethyl)- 61-50-7
Indole, 1-(2-(dimethylamino)ethylamino)-3-phenyl-,hydrochloride 74758-30-8
Indole,1-(2-(dimethylamino)ethyl)-3-(p-ethoxybenzyl)-5-nitro- 101831-86-1
Indole, 3-(2-(dimethylamino)ethyl)-, hydrochloride 13392-38-6
Indole, 5-(dimethylamino)-3-ethyl-, hydrochloride 101831-87-2
Indole, 3-(2-anilinoethyl)-5-(benzyloxy)-,monohydrochloride 101831-87-2
Indole, 3-(2-(N,N-dimethylamino)ethyl)-5-methoxy- 1019-45-0
Indole,3-(2-(dimethylamino)ethyl)-1-(p-methoxybenzyl)-5-methoxy-, monohydrochloride 1019-45-0
Indole, 2-(2-dimethylaminoethyl)-5-methoxy-3-methyl- 41055-69-0
Indole,3-(2-(dimethylamino)ethyl)-5-methoxy-2-methyl- 67292-68-6
Indole,3-(2-(dimethylamino)ethyl)-5-methoxy-1-phenethyl-,monohydrochloride 67292-68-6
Indole,3-(2-(dimethylamino)ethyl)-5-methoxy-1-(3-phenylpropyl)-, monohydrochloride 67292-68-6
Indole, 3-(2-(dimethylamino)ethyl)-1-methyl- 13366-47-7
Indole, 3-(2-(dimethylamino)ethyl)-5-methyl- 22120-39-4
Indole, 3-(2-(dimethylamino)ethyl)-7-methyl- 65882-39-5
Indole,1-((2-(dimethylamino)ethyl)methylamino)-5-methyl-3-phenyl-, hydrochloride 74764-93-5
Indole, 1-(alpha-L-arabinopyranosyl)-6-nitro- 67189-84-8
Indole,1-((2-(dimethylamino)ethyl)methylamino)-3-phenyl-,hydrochloride 57647-35-5
Indole, 3-(2-(dimethylamino)ethyl)-5-methylthio- 5102-11-4
Indole, 3-(2-(dimethylamino)ethyl)-1-phenethyl-,monohydrochloride 5102-11-4
Indole, 3-(2-(dimethylamino)ethyl)-1-phenyl- 109692-21-9
Indole, 3-(2-(dimethylamino)ethyl)-, sulfosalicylate 101831-88-3
Indole, 2-((2-(dimethylamino)ethyl)thio)- 24450-18-8
Indole, 2-((2-(dimethylamino)ethyl)thio)-1-methyl-,monohydrochloride 27292-24-6
Indole, 3-(2-(dimethylamino)ethyl)-4,5,6-trimethoxy- 27292-24-6
Indole, 3-((dimethylamino)methyl)- 87-52-5
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Indole, 3-((dimethylamino)methyl)-5-methoxy- 16620-52-3
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