Search   
MSDS  : Isonicotinamide, 2-propylthio-
CAS  : 14222-60-7
SYNONYMS  : * Ektebin * Peteha * 2-Propylisonicotinylthioamide * 2-Propyl-4-pyridinecarbothioamide * 2-Propyl-4-thiocarbamoylpyridine * 2-Propyl-thioisonicotinamide * Prothionamide * Protion * Protionamid * Protionamide * Protionizina * 4-Pyridinecarbothioamide, 2-propyl- * 9778 R.P. * Tebeform * 1321 TH * Trevintix * Tuberex
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : NS0650000
CHEMICAL NAME : Isonicotinamide, 2-propylthio-
CAS REGISTRY NUMBER : 14222-60-7
BEILSTEIN REFERENCE NO. : 0118164
REFERENCE : 5-22-02-00376 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C9-H12-N2-S
MOLECULAR WEIGHT : 180.29
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Ektebin
* Peteha
* 2-Propylisonicotinylthioamide
* 2-Propyl-4-pyridinecarbothioamide
* 2-Propyl-4-thiocarbamoylpyridine
* 2-Propyl-thioisonicotinamide
* Prothionamide
* Protion
* Protionamid
* Protionamide
* Protionizina
* 4-Pyridinecarbothioamide, 2-propyl-
* 9778 R.P.
* Tebeform
* 1321 TH
* Trevintix
* Tuberex

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1320 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - muscle weakness
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 38,471,1975

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 760 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,726,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1 gm/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - muscle weakness
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 38,471,1975

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,
Japan) Volume(issue)/page/year: 6,726,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - cat
DOSE/DURATION : >1 gm/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - muscle weakness
Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 38,471,1975

*** END OF RECORD ***
Search More   
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Isonicotinamide, N-(2-aminoethyl)- 74484-66-5
Isonicotinamide, N-(5-(p-aminophenoxy)pentyl)- 101578-27-2
Isonicotinamide, N-(3,3-bis(p-chlorophenyl)propyl)- 102311-16-0
Isonicotinamide,N-(3,5-bis(4-pyridyl)-1H-1,2,4-triazolyl)-,dihydrochloride 67292-79-9
Isonicotinamide, N-cyclopropyl- 25764-75-4
Isonicotinamide, 2,6-dichloro-N-cyclopropyl-N-ethyl- 20373-56-2
Isonicotinamide, N,N-diethyl- 530-40-5
Isonicotinamide, N-(2-(diethylamino)ethyl)- 6011-13-8
Isonicotinamide, N-(3-difluoromethoxyphenyl)-,hydrochloride 54231-56-0
Isonicotinamide,N-(5,5-dimethyl-2-oxotetrahydro-3-furyl)- 77694-36-1
1H-Isoindole-1,3(2H)-dione,2-(2-((1-piperidinyl)methyl)-1H-benzimidazol-2-ylmethyl)- 115398-74-8
Isonicotinamide, N-(2,3-dimethylphenyl)-,hydrochloride 54231-55-9
Isonicotinamide, N-(3,4-dimethylphenyl)-,hydrochloride 54231-54-8
Isonicotinamide, N-(2,5-dimethylpyrrol-1-yl)- 5588-11-4
Isonicotinamide, N,N'-ethylenedi- 5588-11-4
Isonicotinamide, 2-ethylthio- 536-33-4
Isonicotinamide, N-(hydroxymethyl)- 13538-44-8
Isonicotinamide, N-(2-indol-2-ylethyl)- 63183-58-4
Isonicotinamide, N-(3-indolylmethyl)- 63183-54-0
Isonicotinamide, N-(3-(3-indolyl)propyl)-,hydrochloride, hydrate 72612-06-7
Isonicotinamide, N-(2-(5-methoxyindol-3-yl)ethyl)- 29745-43-5
1H-Isoindole-1,3(2H)-dione,2-(2-(4-(2-pyridyl)-1-piperazinyl)ethyl)-,hydrochloride 117992-70-8
Isonicotinamide, N-(3-(5-methoxy-3-indolyl)propyl)- 72612-10-3
Isonicotinamide, N,N'-methylenebis(thio-, hydrate 63905-50-0
Isonicotinamide, N-(2-(2-methyl-3-indolyl)ethyl)- 63183-56-2
Isonicotinamide, N-(2-methyl-5-phenylpyrrol-1-yl)- 93317-30-7
Isonicotinamide, N-(4-methyl-1-piperazinylmethyl)- 38221-52-2
Isonicotinamide, N-(morpholinomethyl)- 38221-50-0
Isonicotinamide, N-(4-oxo-2-thioxo-3-thiazolidinyl)- 38221-50-0
Isonicotinamide, 2-propylthio- 14222-60-7
Isonicotinamide, thio-, 1-oxide 63919-16-4
Isonicotinamidine, N-(p-chlorophenyl)- 23565-10-8
1H-Isoindole-1,3(2H)-dione,2-((1-(4-morpholinylmethyl)-1H-benzimidazol-2-yl)methyl)- 115398-75-9
1H-Isoindole-1,3(2H)-dione,2-((4-(1-pyrrolidinyl)-2-butynyl)oxy)-, ethanedioate(2:1) 74500-82-6
Isonicotinamidine, N-(3-chloro-p-tolyl)- 23564-67-2
Isonicotinamidine, N-(3,4-dichlorophenyl)- 23564-32-1
Isonicotinamidine, N-(2,5-dimethoxyphenyl)- 23564-31-0
Isonicotinamidine, N-(m-fluorophenyl)- 23565-11-9
Isonicotinamidine, N-(o-hydroxyphenyl)- 23564-33-2
Isonicotinamidine, N-(o-methoxyphenyl)- 23565-14-2
Isonicotinamidine, N-(p-methoxyphenyl)- 23565-15-3
Isonicotinamidine, N-1-naphthyl- 23565-16-4
Isonicotinamidine, N-2-naphthyl- 23564-66-1
Isonicotinamidine, N-phenyl- 23573-51-5
1H-Isoindole-1,3(2H)-dione,4,5,6,7-tetrahydro-2-(4-chlorophenyl)- 88402-43-1
Isonicotinamidine, N-(2-(2-pyridyl)-4-quinazolinyl)- 91748-42-4
Isonicotinamidine, N-p-tolyl- 23564-34-3
Isonicotinamidine,N-(alpha,alpha,alpha-trifluoro-m-tolyl)- 23565-12-0
Isonicotinamidoxime 1594-57-6
Isonicotinanilide, 4'-(bis(2-chloroethyl)amino)- 21908-17-8

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com| Ads link:todaystock.net