* Acetyl-tropate du diethylamino-1 dimethyl-2,2 propanol-3 chlorhydrate
* Acetylatrolactinsaeureester des
3-diaethylamino-2,2-dimethyl-1-propanolhydrochlorid
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : OD5740000
CHEMICAL NAME : Lactic acid, 2-phenyl-,
3-(diethylamino)-2,2-dimethylpropyl ester, acetate,
hydrochloride
CAS REGISTRY NUMBER : 67465-29-6
LAST UPDATED : 199203
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C20-H31-N-O4.Cl-H
MOLECULAR WEIGHT : 385.98
SYNONYMS/TRADE NAMES :
* Acetyl-tropate du diethylamino-1 dimethyl-2,2 propanol-3 chlorhydrate
* Acetylatrolactinsaeureester des
3-diaethylamino-2,2-dimethyl-1-propanolhydrochlorid
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1250 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 59,149,1938
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 65 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 173,86,1933
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intradermal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1750 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 59,149,1938
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 35 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher
information, see NSAPCC. Volume(issue)/page/year: 173,86,1933
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intradermal
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 550 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
Behavioral - ataxia
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4-
1898- Volume(issue)/page/year: 59,149,1938
*** END OF RECORD ***
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