Jamaica ginger extract
SUBSTANCE DEFINITION :
Adulterated with tri-o-cresyl phosphate
REFERENCE :
JHHBAI Bulletin of the Johns Hopkins Hospital. (Baltimore, MD) V.1-119,
1889-1966. For publisher information, see JHMJAX.
CAS  
:
8037-96-5
SYNONYMS  
:
* Extract of jamaica ginger
* Fluid-extract of jamaica ginger U.S.P.
*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NY5980000
CHEMICAL NAME : Jamaica ginger extract
SUBSTANCE DEFINITION :
Adulterated with tri-o-cresyl phosphate
REFERENCE :
JHHBAI Bulletin of the Johns Hopkins Hospital. (Baltimore, MD) V.1-119,
1889-1966. For publisher information, see JHMJAX.
LAST UPDATED : 199506
DATA ITEMS CITED : 2
COMPOUND DESCRIPTOR : Human
SYNONYMS/TRADE NAMES :
* Extract of jamaica ginger
* Fluid-extract of jamaica ginger U.S.P.
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - man
DOSE/DURATION : 12 gm/kg/7D
TOXIC EFFECTS :
Spinal Cord - demyelination
Spinal Cord - other degenerative changes
Peripheral Nerve and Sensation - structural change in nerve or sheath
REFERENCE :
ANPSAI Archives of Neurology and Psychiatry. (Chicago, IL) V.1-64,
1919-50. For publisher information, see ARNEAS. Volume(issue)/page/year:
25,29,1931
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 284 gm/kg/15W
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
Behavioral - muscle weakness
Lungs, Thorax, or Respiration - other changes
REFERENCE :
JHHBAI Bulletin of the Johns Hopkins Hospital. (Baltimore, MD) V.1-119,
1889-1966. For publisher information, see JHMJAX. Volume(issue)/page/year:
52,39,1933
*** END OF RECORD ***
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