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MSDS  : Luteinizing hormone-releasing hormone, (D-phe(sup 2))-(D-ala(sup 6))-
CAS  : 54784-44-0
SYNONYMS  : * Luteinizing hormone-releasing hormone (pig), 2-D-phenylalanine-6-D-alanine- * (D-Phe(sup 2))-(D-ala(sup 6))-LHRH * (D-Phe(sup 2))-(D-ala(sup 6))-luteinizing hormone-releasing hormone * WY-18,185
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OK6600000
CHEMICAL NAME : Luteinizing hormone-releasing hormone, (D-phe(sup
2))-(D-ala(sup 6))-
CAS REGISTRY NUMBER : 54784-44-0
LAST UPDATED : 198910
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C59-H79-N15-O13
MOLECULAR WEIGHT : 1206.53
COMPOUND DESCRIPTOR : Reproductive Effector
Hormone
SYNONYMS/TRADE NAMES :
* Luteinizing hormone-releasing hormone (pig),
2-D-phenylalanine-6-D-alanine-
* (D-Phe(sup 2))-(D-ala(sup 6))-LHRH
* (D-Phe(sup 2))-(D-ala(sup 6))-luteinizing hormone-releasing hormone
* WY-18,185

*** HEALTH HAZARD DATA ***

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 3750 ug/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 18,1247,1975

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 2500 ug/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant
per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
IJGOAL International Journal of Gynaecology & Obstetrics. (Elsevier
Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.7- 1969-
Volume(issue)/page/year: 16,359,1979

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Rodent - rat
DOSE : 30 mg/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
EDRCAM Endocrine Research Communcations. (New York, NY) V.1-9, 1974-83.
Volume(issue)/page/year: 2,1,1975

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rabbit
DOSE : 12500 ug/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
EDRCAM Endocrine Research Communcations. (New York, NY) V.1-9, 1974-83.
Volume(issue)/page/year: 2,1,1975

*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Luteinizing hormone-releasing hormone, (des-gly(sup10))-, ethylamide 77215-53-3
Luteinizing hormone-releasing hormone, (des-gly(sup10)-(D-leu(sup 6)(N(sup alpha)-Me) leu(sup 7),pro(sup9)-nhet))- 77215-53-3
Luteinizing hormone-releasing hormone, (des-gly(sup10)-D-try(sup 6)-pro)-, ethylamide 77215-53-3
Luteinizing hormone-releasing hormone, (des-his(sup2)-des-gly(sup 10))-, ethylamide 77215-53-3
Luteinizing hormone-releasing hormone, diacetate(salt) 71447-49-9
Luteinizing hormone-releasing hormone, diacetate,tetrahydrate 71447-49-9
Luteinizing hormone-releasing hormone, (D-dmb(sup6))- 71447-49-9
Levorin A1 58591-17-6
Luteinizing hormone-releasing hormone, (D-p-F-phe(sup2)-D-ala(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, Z-(gln(sup1)-des-his(sup 2)-D-pse(sup 6)- des-gly(sup 10))-,ethylamide, acetate 57383-17-2
Luteinizing hormone-releasing hormone, Z-(gln(sup1)-des-his(sup 2)-D-pse(sup 6)- des-gly(sup 10))-,ethylamide, hydrochloride 57383-17-2
Luteinizing hormone-releasing hormone, (L-glu(sup1)-D-phe(sup 2)-pro(sup 3)-D-phe(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (L-glu(sup1)-D-phe(sup 2)-pro(sup 3)-D-trp(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-pglu(sup1),D-phe(sup 2),D-trp(sup 3,6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-glu(sup1)-D-phe(sup 2)-D-trp(sup 3)- D-phe(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-p-glu(sup1)-D-phe(sup 2)-D-trp(sup 3)- D-phe(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (L-glu-pro(sup1)-D-phe(sup 2)-D-trp(sup 3)- D-trp(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-glu(sup1)-D-thi(sup 2)-D-trp(sup 3,6))- 57383-17-2
Levorin A3 58591-23-4
Luteinizing hormone-releasing hormone, (D-his(sub6)(IM-bzl)-pro(sup 9)-NEt)- 58591-23-4
Luteinizing hormone-releasing hormone,2-L-histidine-6-L-glycine- 58591-23-4
Luteinizing hormone-releasing hormone,((imbzl)-D-his(sup 6)-pro(sup 9)-net)- 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6))- 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6),des-gly(sup 10))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6),des-gly-NH2(sup 10))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6)-des-gly(sup 10)-pro(sup 9))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6)(N(sup alpha)-ME)leu(sup 7))- 58591-23-4
Luteinizing hormone-releasing hormone,6-(2-methylalanine) 60452-40-6
Levulinamide, N,N-diethyl- 6946-94-7
Luteinizing hormone-releasing hormone, monoacetate,tetrahydrate 6946-94-7
Luteinizing hormone-releasing hormone, (D-nia(sup6),pro(sup 9)-nhet)- 6946-94-7
Luteinizing hormone-releasing hormone, (D-phe(sup2))- 6946-94-7
Luteinizing hormone-releasing hormone, (D-phe(sup2))-(D-ala(sup 6))- 54784-44-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-ala(sup 3)-ala(sup 4)-D-phe(sup 6))- 54784-44-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-arg(sup 6))- 57292-40-7
Luteinizing hormone-releasing hormone, (D-phe(sup2)-arg(sup 3)-D-phe(sup 6))- 57292-40-7
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-leu(sup 6))- 56269-16-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-leu(sup 3)-D-phe(sup 6))- 56269-16-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-leu(sup 3)-D-trp(sup 6))- 56269-16-0
Levulinamide, N,N-dimethyl- 13458-51-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-leu(sup 3)-D-trp(sup 6)-ME-leu(sup 7))- 13458-51-0
Luteinizing hormone-releasing hormone, (D-phe(sup2))-(2-ME-ala(sup 6))- 57292-43-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-ME-leu(sup 3)-D-phe(sup 6))- 57292-43-0
Luteinizing hormone-releasing hormone, (phe(sup2)-nva(sup 3)-D-ala(sup 6)- des-gly(sup 10))-,ethylamide 57292-43-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-nva(sup 3)-D-phe(sup 6))- 57292-43-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-phe(sup 6))- 57292-41-8
Luteinizing hormone-releasing hormone, (D-phe(sup2)-phe(sup 3)-D-phe(sup 6))- 58811-17-9
Luteinizing hormone-releasing hormone, (D-phe(sup2)-phe(sup 5)-D-phe(sup 6))- 58811-17-9
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-(PH)gly(sup 6))- 56558-32-8

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