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MSDS  : Luteinizing hormone-releasing hormone, (D-leu(sup 6),des-gly(sup 10))-, ethylamide
CAS  : 58591-23-4
SYNONYMS  : * D-Leu(sup 6),des-gly(sup 10)-Gnrh ethylamide * (D-Leu(sup 6),des-gly(sup 10))-gonadotropin releasing hormone ethylamide * (D-Leu(sup 6),des-gly(sup 10))-LHRH ethylamide * (D-Leu(sup 6),des-gly(sup 10))-luteinizing hormone-releasing hormone ethylamide
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : OK6515000
CHEMICAL NAME : Luteinizing hormone-releasing hormone, (D-leu(sup
6),des-gly(sup 10))-, ethylamide
LAST UPDATED : 198910
DATA ITEMS CITED : 2
COMPOUND DESCRIPTOR : Reproductive Effector
Hormone
SYNONYMS/TRADE NAMES :
* D-Leu(sup 6),des-gly(sup 10)-Gnrh ethylamide
* (D-Leu(sup 6),des-gly(sup 10))-gonadotropin releasing hormone ethylamide
* (D-Leu(sup 6),des-gly(sup 10))-LHRH ethylamide
* (D-Leu(sup 6),des-gly(sup 10))-luteinizing hormone-releasing hormone
ethylamide

*** HEALTH HAZARD DATA ***

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 11200 ng/kg
SEX/DURATION : male 14 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
accessory glands
REFERENCE :
BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W.
Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year:
30,646,1984

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 16800 ng/kg
SEX/DURATION : male 21 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
sperm morphology, motility, and count)
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S,
Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 41,309,1984

*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Luteinizing hormone-releasing hormone, (des-gly(sup10))-, ethylamide 77215-53-3
Luteinizing hormone-releasing hormone, (des-gly(sup10)-(D-leu(sup 6)(N(sup alpha)-Me) leu(sup 7),pro(sup9)-nhet))- 77215-53-3
Luteinizing hormone-releasing hormone, (des-gly(sup10)-D-try(sup 6)-pro)-, ethylamide 77215-53-3
Luteinizing hormone-releasing hormone, (des-his(sup2)-des-gly(sup 10))-, ethylamide 77215-53-3
Luteinizing hormone-releasing hormone, diacetate(salt) 71447-49-9
Luteinizing hormone-releasing hormone, diacetate,tetrahydrate 71447-49-9
Luteinizing hormone-releasing hormone, (D-dmb(sup6))- 71447-49-9
Levorin A1 58591-17-6
Luteinizing hormone-releasing hormone, (D-p-F-phe(sup2)-D-ala(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, Z-(gln(sup1)-des-his(sup 2)-D-pse(sup 6)- des-gly(sup 10))-,ethylamide, acetate 57383-17-2
Luteinizing hormone-releasing hormone, Z-(gln(sup1)-des-his(sup 2)-D-pse(sup 6)- des-gly(sup 10))-,ethylamide, hydrochloride 57383-17-2
Luteinizing hormone-releasing hormone, (L-glu(sup1)-D-phe(sup 2)-pro(sup 3)-D-phe(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (L-glu(sup1)-D-phe(sup 2)-pro(sup 3)-D-trp(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-pglu(sup1),D-phe(sup 2),D-trp(sup 3,6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-glu(sup1)-D-phe(sup 2)-D-trp(sup 3)- D-phe(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-p-glu(sup1)-D-phe(sup 2)-D-trp(sup 3)- D-phe(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (L-glu-pro(sup1)-D-phe(sup 2)-D-trp(sup 3)- D-trp(sup 6))- 57383-17-2
Luteinizing hormone-releasing hormone, (D-glu(sup1)-D-thi(sup 2)-D-trp(sup 3,6))- 57383-17-2
Levorin A3 58591-23-4
Luteinizing hormone-releasing hormone, (D-his(sub6)(IM-bzl)-pro(sup 9)-NEt)- 58591-23-4
Luteinizing hormone-releasing hormone,2-L-histidine-6-L-glycine- 58591-23-4
Luteinizing hormone-releasing hormone,((imbzl)-D-his(sup 6)-pro(sup 9)-net)- 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6))- 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6),des-gly(sup 10))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6),des-gly-NH2(sup 10))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6)-des-gly(sup 10)-pro(sup 9))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6))-, ethylamide 58591-23-4
Luteinizing hormone-releasing hormone, (D-leu(sup6)(N(sup alpha)-ME)leu(sup 7))- 58591-23-4
Luteinizing hormone-releasing hormone,6-(2-methylalanine) 60452-40-6
Levulinamide, N,N-diethyl- 6946-94-7
Luteinizing hormone-releasing hormone, monoacetate,tetrahydrate 6946-94-7
Luteinizing hormone-releasing hormone, (D-nia(sup6),pro(sup 9)-nhet)- 6946-94-7
Luteinizing hormone-releasing hormone, (D-phe(sup2))- 6946-94-7
Luteinizing hormone-releasing hormone, (D-phe(sup2))-(D-ala(sup 6))- 54784-44-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-ala(sup 3)-ala(sup 4)-D-phe(sup 6))- 54784-44-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-arg(sup 6))- 57292-40-7
Luteinizing hormone-releasing hormone, (D-phe(sup2)-arg(sup 3)-D-phe(sup 6))- 57292-40-7
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-leu(sup 6))- 56269-16-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-leu(sup 3)-D-phe(sup 6))- 56269-16-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-leu(sup 3)-D-trp(sup 6))- 56269-16-0
Levulinamide, N,N-dimethyl- 13458-51-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-leu(sup 3)-D-trp(sup 6)-ME-leu(sup 7))- 13458-51-0
Luteinizing hormone-releasing hormone, (D-phe(sup2))-(2-ME-ala(sup 6))- 57292-43-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-ME-leu(sup 3)-D-phe(sup 6))- 57292-43-0
Luteinizing hormone-releasing hormone, (phe(sup2)-nva(sup 3)-D-ala(sup 6)- des-gly(sup 10))-,ethylamide 57292-43-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-nva(sup 3)-D-phe(sup 6))- 57292-43-0
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-phe(sup 6))- 57292-41-8
Luteinizing hormone-releasing hormone, (D-phe(sup2)-phe(sup 3)-D-phe(sup 6))- 58811-17-9
Luteinizing hormone-releasing hormone, (D-phe(sup2)-phe(sup 5)-D-phe(sup 6))- 58811-17-9
Luteinizing hormone-releasing hormone, (D-phe(sup2)-D-(PH)gly(sup 6))- 56558-32-8

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