RTECS NUMBER : OO7177000
CHEMICAL NAME : Mandelic acid, alpha-cyclopentyl-,
1-ethyl-3-pyrrolidinyl ester, hydrochloride
CAS REGISTRY NUMBER : 60573-74-2
LAST UPDATED : 199010
DATA ITEMS CITED : 2
MOLECULAR FORMULA : C19-H27-N-O3.Cl-H
MOLECULAR WEIGHT : 353.93
WISWESSER LINE NOTATION : T5NTJ A2 COVXQR&- AL5TJ &GH
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* AHR 379
* Benzeneacetic acid, alpha-cyclopentyl-alpha-hydroxy-,
1-ethyl-3-pyrrolidinyl ester, HCl
* alpha-Cyclopentylmandelic acid 1-ethyl-3-pyrrolidinyl ester hydrochloride
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 480 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC)
V.1-5, 1959-62. For publisher information, see JMCMAR.
Volume(issue)/page/year: 2,523,1960
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 230 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - convulsions or effect on seizure threshold
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC)
V.1-5, 1959-62. For publisher information, see JMCMAR.
Volume(issue)/page/year: 2,523,1960
*** END OF RECORD ***
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