*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : PB0370000
CHEMICAL NAME : Methanesulfenyl chloride, trichloro-
CAS REGISTRY NUMBER : 594-42-3
BEILSTEIN REFERENCE NO. : 0506034
REFERENCE : 4-03-00-00290 (Beilstein Handbook Reference)
LAST UPDATED : 199712
DATA ITEMS CITED : 34
MOLECULAR FORMULA : C-Cl4-S
MOLECULAR WEIGHT : 185.87
WISWESSER LINE NOTATION : GXGGSG
COMPOUND DESCRIPTOR : Primary Irritant
SYNONYMS/TRADE NAMES :
* Clairsit
* Mercaptan methylique perchlore
* Perchlormethylmerkaptan
* Perchloromethyl mercaptan
* RCRA waste number P118
* Trichloromethane sulfenyl chloride
* Trichloromethanesulphenyl chloride
* Trichloromethylsulfenyl chloride
* Trichloromethylsulphenyl chloride
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 500 mg/24H
REACTION SEVERITY : Severe
REFERENCE :
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,"
Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu
Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,13,1972
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration into the eye
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 50 ug/24H
REACTION SEVERITY : Severe
REFERENCE :
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,"
Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu
Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,13,1972
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 82600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,"
Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu
Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,13,1972
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 11 ppm/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
42,417,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 25 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Lungs, Thorax, or Respiration - dyspnea
Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0533569
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Gastrointestinal - hypermotility, diarrhea
Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0533569
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 296 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,97,1982
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 10 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
Gastrointestinal - other changes
Skin and Appendages - hair
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0533569
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
Volume(issue)/page/year: NX#06768
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 1410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
42,417,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 500 uL/kg
TOXIC EFFECTS :
Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: OTS0533569
*** REVIEWS ***
ACGIH TLV-TWA 0.76 mg/m3 (0.1 ppm)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 0.1 ppm (0.8 mg/m3)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
3,202,1971
OSHA PEL (Gen Indu):8H TWA 0.1 ppm (0.8 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1910.1000,1994
OSHA PEL (Construc):8H TWA 0.1 ppm (0.8 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1926.55,1994
OSHA PEL (Shipyard):8H TWA 0.1 ppm (0.8 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
29,1915.1000,1993
OSHA PEL (Fed Cont):8H TWA 0.1 ppm (0.8 mg/m3)
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt.
of Documents, Washington, DC 20402) Volume(issue)/page/year:
41,50-204.50,1994
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-AUSTRALIA:TWA 0.1 ppm (0.8 mg/m3) JAN 1993
OEL-BELGIUM:TWA 0.1 ppm (0.76 mg/m3) JAN 1993
OEL-DENMARK:TWA 0.1 ppm (0.8 mg/m3) JAN 1993
OEL-FINLAND:STEL 0.1 ppm (0.8 mg/m3) JAN 1993
OEL-FRANCE:TWA 0.1 ppm (0.8 mg/m3) JAN 1993
OEL-THE NETHERLANDS:TWA 0.1 ppm (0.8 mg/m3) JAN 1993
OEL-THE PHILIPPINES:TWA 0.1 ppm (0.8 mg/m3) JAN 1993
OEL-SWITZERLAND:TWA 0.1 ppm (0.8 mg/m3);STEL 0.2 ppm (1.6 mg/m3) JAN 1993
OEL-TURKEY:TWA 0.1 ppm (0.8 mg/m3) JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO PERCHLOROMETHYL MERCAPTAN-air:10H TWA 0.1 ppm
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 54800
No. of Facilities: 324 (estimated)
No. of Industries: 6
No. of Occupations: 17
No. of Employees: 9112 (estimated)
No. of Female Employees: 1677 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8978;8EHQ-0892-9092
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| NAME | CAS |
4,7-Methano-1H-isoindole-1,3(2H)-dione,3a,4,7,7a-tetrahydro-2-(4-(2-propynyloxy)phenyl)-
| 39488-06-7 |
4,7-Methano-1H-isoindole-1,3(2H)-dione,3a,4,7,7a-tetrahydro-2-(4-(1-pyrrolidinyl)-2-butynyl)-, monohydrochloride
| 39488-11-4 |
4,7-Methanoisoindole-2-ethanol, 4,7-dihydro-
| 78593-81-4 |
4,7-Methanoisoindole-2-ethanol, 4,5,6,7-tetrahydro-
| 63023-85-8 |
Methanearsonic acid, compd. with2,2',2''-nitrilotriethanol
| 5902-97-6 |
Methaneperoxic acid
| 107-32-4 |
4,7-Methanoisoindole,4,5,6,7-tetrahydro-2-tert-butyl-
| 78593-85-8 |
4,7-Methanoisoindole, 4,5,6,7-tetrahydro-2-phenyl-
| 78593-82-5 |
4,7-Methanoisoindole, 4,5,6,7-tetrahydro-2-(p-tolyl)-
| 30451-37-7 |
4,7-Methanoisoindoline,3a,7a-dihydro-2-(diethylaminoethyl)-
| 74037-58-4 |
4,7-Methanoisoindoline,3a,7a-dihydro-2-(3-morpholinopropyl)-
| 73855-76-2 |
4,7-Methanoisoindoline-2-ethanol, hexahydro-
| 63023-83-6 |
4,7-Methanoisoindoline, hexahydro-2-tert-butyl-
| 78593-87-0 |
4,7-Methanoisoindoline, hexahydro-2-phenyl-
| 78593-86-9 |
4,7-Methanoisoindoline, 3a,4,7,7a-tetrahydro-,hydrochloride
| 15997-94-1 |
4,7-Methanoisoindolinium,3a,7a-dihydro-2-(2-(diethylmethylammonio)ethyl)-2-methyl-, diiodide
| 74051-64-2 |
Methanesulfenyl chloride, dichlorofluoro-
| 2712-93-8 |
4,7-Methanoisoindolinium,3a,7a-dihydro-2-methyl-2-(3-(4-methyl-4-morpholinio)propyl)-, diiodide
| 74037-59-5 |
Methanol
| 67-56-1 |
Methanol, benzoyl-, compd with morpholine acetate
| 67-56-1 |
Methanol, (benzylnitrosamino)-, acetate (ester)
| 63531-81-7 |
Methanol,(4,6-bis(bis(butoxymethyl)amino)-s-triazin-2-ylimino)di-
| 74037-60-8 |
Methanol,((6-bis(2-chloroethoxymethyl)amino)-s-triazine-2,4-diyl)(N,N'-bis(2-chloro ethoxy methyldinitrilo))di-
| 74037-61-9 |
Methanol, bis(p-chlorophenyl)cyclopropyl-
| 14088-71-2 |
Methanol,((4,6-bis(dimethylamino)-s-triazin-2-yl)methylamino)-
| 16269-01-5 |
Methanol,((6-bis(1-hydroxy-2-propenyl)amino)-s-triazine-2,4-diyl)dinitrilotetra-
| 74037-62-0 |
Methanol, (butyldimethylsilyl)-, carbamate
| 3124-39-8 |
Methanesulfenyl chloride, trichloro-
| 594-42-3 |
Methanol, (tert-butyldioxy)-
| 17742-78-8 |
Methanol, (butylmethylsilylene)di-, dicarbamate(ester)
| 3124-49-0 |
Methanol, (butylnitrosoamino)-
| 76671-53-9 |
Methanol,(5-chloro-3-(5-chloro-2-hydroxybenzyl)-2-hydroxyphenyl)-
| 76671-53-9 |
Methanol, cyclohexylphenyl-
| 945-49-3 |
Methanol, cyclopropyldiphenyl-
| 5785-66-0 |
Methanol, compd. with(+-)-alpha-(2-dimethylamino)-1-methylethyl-alpha-phenylphenethyl propionate (1:1)
| 2621-61-6 |
Methanol, (dimethylethylsilyl)-, carbamate
| 2621-61-6 |
Methanol, (dimethylphosphino)-
| 33796-25-7 |
Methanol, (dimethylpropylsilyl)-, carbamate
| 3124-41-2 |
Methanesulfinic acid, 1-(p-butoxyanilino)-, sodiumsalt
| 3124-41-2 |
Methanol, diphenyl(2-(4-pyridyl)cyclopropyl)-, (E)-
| 4904-00-1 |
Methanol, diphenyl(2-(4-pyridyl)cyclopropyl)-,hydrochloride
| 2364-72-9 |
Methanol, (1,2-ethanediylbis(nitroimino))bis-,diacetate (ester)
| 14168-48-0 |
Methanol, (ethylnitrosoamino)-
| 86860-62-0 |
Methanol, methoxy-ONN-azoxy-, acetate (ester)
| 67293-86-1 |
Methanol, (methyl-ONN-azoxy)-
| 590-96-5 |
Methanol, (methyl-ONN-azoxy)-, acetate (ester)
| 592-62-1 |
Methanol, (methylazoxy)-, benzoate (ester)
| 3527-05-7 |
Methanol,methyl-3-cyclohexenyl
| 17264-01-6 |
Methanol, (methylnitramino)-
| 32818-80-7 |
Methanesulfinic acid, 1-((6-butoxy-3-pyridyl)amino)-,sodium salt
| 32818-80-7 |
|
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