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MSDS  : Phosphonic acid, ethyl-, ethyl p-nitrophenyl ester
CAS  : 546-71-4
SYNONYMS  : * Armin (ester) * Armine * Arminum * Ethoxy-4-nitrophenyloxyethyl-phosphineoxide * Ethyl-4-nitrophenyl ethylphosphonate * Ethylphosphonic acid ethyl p-nitrophenyl ester
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : SZ8020000
CHEMICAL NAME : Phosphonic acid, ethyl-, ethyl p-nitrophenyl ester
CAS REGISTRY NUMBER : 546-71-4
OTHER CAS REGISTRY NOS. : 8053-54-1
BEILSTEIN REFERENCE NO. : 1990082
REFERENCE : 4-06-00-01319 (Beilstein Handbook Reference)
LAST UPDATED : 199709
DATA ITEMS CITED : 6
MOLECULAR FORMULA : C10-H14-N-O5-P
MOLECULAR WEIGHT : 259.22
WISWESSER LINE NOTATION : WNR DOPO&2&O2
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Armin (ester)
* Armine
* Arminum
* Ethoxy-4-nitrophenyloxyethyl-phosphineoxide
* Ethyl-4-nitrophenyl ethylphosphonate
* Ethylphosphonic acid ethyl p-nitrophenyl ester

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 230 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,411,1968

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 250 ug/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - bronchiolar constriction
Lungs, Thorax, or Respiration - other changes
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 42,299,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1862 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
(usually neuromuscular blockage)
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year:
35,806,1980

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,411,1968

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPTOAN Russian Pharmacology and Toxicology (English Translation).
Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
UK) V.30- 1967- Volume(issue)/page/year: 42,106,1979

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 460 ug/kg
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation
of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1-
1967- Volume(issue)/page/year: 3,508,1969

*** END OF RECORD ***
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ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
Phosphonic acid,(3-(4-(dimethylamino)phenyl)-4,5-dihydro-5-isoxazolyl)-, monohydrobromide 125674-86-4
Phosphonic acid, dimethyl ester 868-85-9
Phosphonic acid,(3-(1,1-dimethylethyl)-4,5-dihydro-5-isoxazolyl)- 125674-52-4
Phosphonic acid,(4-(diphenylhydroxymethyl)piperidino)-, dibutyl ester 125674-52-4
Phosphonic acid, (dithiodimethylene)di-, tetramethylester 32674-23-0
Phosphonic acid,(4-(di-o-tolylhydroxymethyl)piperidino)-, diethylester 32674-23-0
Phosphonic acid, dodecyl- 5137-70-2
Phosphonic acid, (1,2-epoxypropyl)-, (1R,2S)-(-)- 23155-02-4
Phosphonic acid, (1,2-epoxypropyl)-, calcium salt(1:1), (1R,2S)-(-)- 26016-98-8
Phosphonic acid, 2,3-epoxypropyl-, diethyl ester 7316-37-2
Phosphine oxide, hexyldipentyl- 74038-20-3
Phosphonic acid, (1,2-epoxypropyl)-, disodium salt(1R,2S) (-)- 26016-99-9
Phosphonic acid, 1,2-ethanediylbis- 6145-31-9
Phosphonic acid, ethenyl- 1746-03-8
Phosphonic acid, ethenyl-,bis(2-((butoxymethylphosphinyl)oxy)ethyl) ester 53529-45-6
Phosphonic acid, (2-ethoxyethyl)-, diethyl ester 5191-35-5
Phosphonic acid, (m-ethylaminophenyl)- 100860-49-9
Phosphonic acid, ethyl-, bis(p-chlorophenyl) ester 100860-49-9
Phosphonic acid, ethyl-, butyl p-nitrophenyl ester 71002-67-0
Phosphonic acid, ethyl-, p-chlorophenyl methyl ester 33232-87-0
Phosphonic acid, ethyl-, cyclic methylene-o-phenyleneester 5853-68-9
Phosphine oxide,1,4-piperazinediylbis(bis(1-aziridinyl)- 738-99-8
Phosphonic acid, ethyl-, ethyl ester, ester withp-hydroxybenzamide 74038-41-8
Phosphonic acid, ethyl, O-ethylO-(2-(ethylthio)-6-methyl-4-pyrimidinyl) ester 25537-46-6
Phosphonic acid, ethyl-, ethyl methyl ester 5301-65-5
Phosphonic acid, ethyl-, ethyl p-nitrophenyl ester 546-71-4
Phosphonic acid, (2-ethyl-1-hydroxyhexyl)- 7506-91-4
Phosphonic acid, ethyl-, isopropyl p-nitrophenylester 7284-58-4
Phosphonic acid, ethyl-, methyl (p-cyanophenyl) ester 33232-88-1
Phosphonic acid, ethyl-, methylp-(methylsulfonyl)phenyl ester 33267-37-7
Phosphonic acid, ethyl-, methyl p-nitrophenyl ester 15536-01-3
Phosphonic acid, ethyl-, methyl p-tolyl ester 33232-85-8
Phosphine oxide,1,4-piperazinediylbis(bis(1-aziridinyl)-, plusN-(5-(aminosulfonyl)-1,3,4- thiadiazol-2-yl)acetamide 72060-03-8
Phosphonic acid, ethyl-, monoethyl ester 7305-61-5
Phosphonic acid, ethylthiomethyl-, dibutyl ester 74038-42-9
Phosphonic acid, ((ethylthio)methylidyne)tri-,hexaethyl ester 3247-33-4
Phosphonic acid,((ethylthio)(phenylthio)methylene)bis-, tetraethylester 63869-22-7
Phosphonic acid,(5-(3-fluorobenzoyl)-2,4-dihydro-3H-pyrazol-3-ylidene)bis-, tetraethyl ester 132508-17-9
Phosphonic acid, fluoro-, ethyl isopropyl ester 132508-17-9
Phosphonic acid, p-fluorophenyl-,bis(2-(dimethylamino)ethyl) ester 339-32-2
Phosphonic acid,(3-(4-fluorophenyl)-4,5-dihydro-5-isoxazolyl)-,dimethyl ester 125674-80-8
Phosphonic acid,(3-(formylhydroxyamino)-1-propenyl)-, (E)- 66508-88-1
Phosphonic acid,(3-(formylhydroxyamino)-1-propenyl)-, monopotassiumsalt, (E)- 66508-52-9
Phosphine oxide, tri(mixed(C4-C7)-alkyl)- 66508-52-9
Phosphonic acid, (3-(formylhydroxyamino)propyl)-,monosodium salt 66508-37-0
Phosphonic acid, heptyl-, O-ethyl O-(p-nitrophenyl)ester 3015-77-8
Phosphonic acid, (hexahydro-1H-azepin-1-yl)-, cyclicO,O,O',O'-neopentanetetrayl ester 19341-49-2
Phosphonic acid,(hexahydro-3,6-epoxyphthalimido)methyl-, diethylester 74038-43-0
Phosphonic acid, hexamethylenedi-, tetrabutyl ester 63904-89-2
Phosphonic acid,(1,6-hexanediylbis(nitrilobis(methylene)))tetrakis- 23605-74-5

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