LILLY ELI & PHARMACEUTICAL DIV -- VL7051 DOBUTAMINE HYDROCHLORIDE FOR IN
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Material Safety Data Sheet
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MSDS Num: BXPJR
MSDS NAME: VL7051 DOBUTAMINE HYDROCHLORIDE FOR INJECTION
Responsible Party
Name: LILLY ELI & CO PHARMACEUTICAL DIV
Address: 307 E MCCARTY ST
City: INDIANAPOLIS IN 48285-5000
Info Phone: 317-276-2000/317-276-3494
Emergency Phone Number: 317-276-2000/317-276-3494
Review Ind: Y
Published: Y
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Preparer Co. when other than Responsible Party Co.
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Assigned Ind: Y
Name: LILLY ELI & CO PHARMACEUTICAL DIV
Address: LILLY CORPORATE CENTER
City: INDIANAPOLIS IN 46285
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Contractor Summary
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Name: LILLY ELI & CO PHARMACEUTICAL DIV
Address: LILLY CORPORATE CENTER
City: INDIANAPOLIS IN 46285
Phone: 317-276-2000
Name: LILLY ELI AND CO PHARMACEUTICAL DIV
Address: LILLY CORPORATE CENTER
City: INDIANAPOLIS IN 46285
Phone: 317-276-2000
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Ingredients
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Cas: 52663-81-7
RTECS #: CZ9001000
Name: 1,2-BENZENEDIOL,4-(2-((3-(4-HYDROXYPHENYL)-1-METHYLPROPYL)
AMINO)ETHYL)-HYDROCHLORIDE *95-1*
% Wt: 52-73
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Cas: 69-65-8
RTECS #: OP2060000
Name: MINNITOL, D- (MANNA SUGAR); MANNITOL
% Wt: 27-48
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Health Hazards Data
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LD50 LC50 Mixture: ORAL DL50(RAT): 500 MG/KG (SEE SUPP)
Route Of Entry Inds - Inhalation: YES
Skin: NO
Ingestion: NO
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: DOBUTAMINE HYDROCHLORIDE-EYE IRRITATION HAS BEEN REPORTED
FROM OCCUPATIONAL EXPOSURE.
Explanation Of Carcinogenicity: NONE
Signs And Symptions Of Overexposure: DOBUTAMINE HYDROCHLORIDE: IRRITATION
First Aid: EYES: FLUSH W/A STEADY, GENTLE STREAM OF WATER FOR 15 MINS. SKIN:
WASH W/PLENTY OF SOAP & WATER. INHALATION: MOVE TO FRESH AIR. IF NOT
BREATHING, GIVE CPR. INGESTION: DON'T INDUCE VOMITING. IF AVAILAB LE, GIVE
ACTIVATED CHARCOAL (6-8 HEAPING TEASPOONS) W/2-3 GLASSES OF WATER. DON'T GIVE
ANYTHING BY MOUTH IF UNCONSCIOUS. OBTAIN MEDICAL ATTENTION IN ALL CASES.
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Handling and Disposal
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Spill Release Procedures: CONTAIN DRY MATERIAL BY SWEEPING UP/VACUUMING.
VACUUMING MAY DISPERSE DUST IF APPROPRIATE DUST COLLECTION FILTER ISN'T PART
OF THE VACUUM. WEAR PROTECTIVE EQUIPMENT TO AVOID EXPOSURE.
Waste Disposal Methods: DISPOSE OF ANY CLEANUP MATERIALS & WASTE RESIDUE IN
ACCORDANCE W/LOCAL, STATE & FEDERAL REGULATIONS.
Other Precautions: AVOID EXPOSURE & SKIN CONTACT.
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Fire and Explosion Hazard Information
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Extinguishing Media: WATER, CO2, DRY CHEMICAL, FOAM/HALON
Unusual Fire/Explosion Hazard: MAY FORM DUST MIXTURES IN AIR WHICH COULD
EXPLODE IF SUBJECTED TO AN IGNITION SOURCE. MAY EMIT TOXIC CHLORIDE FUMES
WHEN HEATED TO DECOMPOSITION.
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Control Measures
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Respiratory Protection: IN PRODUCTION SETTINGS, AIRLINE-SUPPLIED, HOOD-TYPE
RESPIRATORS ARE PREFERRED.
Ventilation: LABORATORY FUME HOOD/LOCAL EXHAUST VENTILATION
Protective Gloves: CHEMICAL RESISTANT
Eye Protection: CHEMICAL GOGGLES/FACE SHIELD
Other Protective Equipment: SAFETY GLASSES, CHEMICAL RESISTANT BODY COVERING
Work Hygienic Practices: REMOVE/LAUNDER CONTAMINATED CLOTHING BEFORE REUSE.
Supplemental Safety and Health: ORAL LD50 INFORMATION IS FOR: DOBUTAMINE
HYDROCHLORIDE.
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Physical/Chemical Properties
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PH: 2.5-5
Solubility in Water: COMPLETE
Appearance and Odor: WHITE TO OFF-WHITE PLUG W/NO ODOR
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Reactivity Data
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Stability Indicator: YES
Materials To Avoid: STRONG OXIDIZING AGENTS & ELECTRICAL EQUIPMENT
Hazardous Decomposition Products: CHLORIDE FUMES
Hazardous Polymerization Indicator: NO
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Toxicological Information
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Ecological Information
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MSDS Transport Information
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Regulatory Information
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Other Information
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HAZCOM Label
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MSDS NAME: VL7051 DOBUTAMINE HYDROCHLORIDE FOR INJECTION
Assigned IND: Y
Company: LILLY ELI & CO PHARMACEUTICAL DIV
Street: LILLY CORPORATE CENTER
City: INDIANAPOLIS IN
Zipcode: 46285
Health Emergency Phone: 317-276-2000/317-276-3494
Label Required IND: Y
Date Of Label Review: 12/16/1998
Status Code: C
Label Date: 12/16/1998
Origination Code: G
Hazard And Precautions: DOBUTAMINE HYDROCHLORIDE-EYE IRRITATION HAS BEEN
REPORTED FROM OCCUPATIONAL EXPOSURE.
DOBUTAMINE HYDROCHLORIDE: IRRITATIO N
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Disclaimer (provided with this information by the compiling agencies): This
information is formulated for use by elements of the Department of Defense.
The United States of America in no manner whatsoever expressly or implied
warrants, states, or intends said information to have any application, use or
viability by or to any person or persons outside the Department of Defense
nor any person or persons contracting with any instrumentality of the United
States of America and disclaims all liability for such use. Any person
utilizing this instruction who is not a military or civilian employee of the
United States of America should seek competent professional advice to verify
and assume responsibility for the suitability of this information to their
particular situation regardless of similarity to a corresponding Department
of Defense or other government situation.
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