DAKO CORPORATION -- TRIS-BUFFERED SALINE W/TWEEN 20 (TBST) 10X CO
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Material Safety Data Sheet
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MSDS Num: CJWTV
MSDS NAME: TRIS-BUFFERED SALINE W/TWEEN 20 (TBST) 10X CONCENTRATE,S3306
Responsible Party
Name: DAKO CORPORATION
Address: 6392 VIA REAL
City: CARPINTERIA CA 93013
Info Phone: 805-566-6655
Emergency Phone Number: 805-566-6655
Review Ind: Y
Published: Y
=======================================================
Contractor Summary
=======================================================
Name: DAKO CORPORATION
Address: 6392 VIA REAL
City: CARPINTERIA CA 93013
Phone: 805-566-6655
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Item Description Information
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Ingredients
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Cas: 7647-14-5
RTECS #: VZ4725000
Name: SODIUM CHLORIDE
% low Wt: 15.
% high Wt: 20.
Other REC Limits: N/K (FP N)
OSHA PEL: N/K (FP N)
OSHA STEL: N/K (FP N)
ACGIH TLV: N/K (FP N)
ACGIH STEL: N/K (FP N)
------------------------------
Cas: 77-86-1
RTECS #: TY2900000
Name: 1,3-PROPANEDIOL, 2-AMINO-2-(HYDROXYMETHYL)-; (TRIZMA BASE)
% low Wt: 6.
% high Wt: 7.
Other REC Limits: N/K (FP N)
OSHA PEL: N/K (FP N)
OSHA STEL: N/K (FP N)
ACGIH TLV: N/K (FP N)
ACGIH STEL: N/K (FP N)
------------------------------
Cas: 9005-64-5
RTECS #: TR7400000
Name: POLYSORBATE 20; (POLYOXYTHELENESORBITAN MONOLAURATE (TWEEN 20))
Percent by Wt: 1.
Other REC Limits: N/K (FP N)
OSHA PEL: N/K (FP N)
OSHA STEL: N/K (FP N)
ACGIH TLV: N/K (FP N)
ACGIH STEL: N/K (FP N)
------------------------------
Name: NON-HAZARDOUS INGREDIENTS
Other REC Limits: N/K (FP N)
OSHA PEL: N/K (FP N)
OSHA STEL: N/K (FP N)
ACGIH TLV: N/K (FP N)
ACGIH STEL: N/K (FP N)
=======================================================
Health Hazards Data
=======================================================
LD50 LC50 Mixture: SEE TOXICOLOGICAL INFORMATION.
Route Of Entry Inds - Inhalation: YES
Skin: YES
Ingestion: YES
Carcinogenicity Inds - NTP: NO
IARC: NO
OSHA: NO
Effects of Exposure: MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN
ABSORPTION. MAY CAUSE IRRITATION. TO THE BEST OF MANUFACTURER'S KNOWLEDGE,
THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHL
Y INVESTIGATED.
Signs And Symptions Of Overexposure: SEE HEALTH HAZARDS.
First Aid: INHALATION: REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN. IF EXPOSURE SYMPTOMS
PERSIST, SEEK MEDICAL ATTENTION. SKIN: IMMEDIATELY WASH WI TH SOAP AND
COPIOUS AMOUNTS OF WATER. REMOVE AND WASH CONTAMINATED CLOTHING IMMEDIATELY.
EYES: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
MINUTES. ASSURE ADEQUATE FLUSHING BY SEPA RATING THE EYELIDS WITH FINGERS. IF
EXPOSURE SYMPTOMS DEVELOP, SEEK MEDICAL ATTENTION. INGESTION: WASH OUT MOUTH
WITH WATER PROVIDED PERSON IS CONSCIOUS. SEEK MEDICAL ATTENTION.
=======================================================
Handling and Disposal
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Spill Release Procedures: PERS PROT EQUIP (INCL NIOSH APPRVD RESP) & CLTHG
IS REC DURING ALL CLEAN-UP PROC. REFER TO CTL MEASURES SECTION FOR ADDNL INFO
ON EXPOS CTLS & PERS PROT EQUIP. ENVIRON PREC: DATA NOT YET AVAIL. AVOID
PHYSICAL CONT DURING REMOVAL. NIOSH APPRVD RESP IS REC WHEN IRRITANT/NUISANCE
VAPS ARE PRDCED. ABSORB SPILLED SUBSTANCE USING PAPER TOWELS/ABSORB PADS.
PLACE IN BAG & HOLD FOR DISP. (SUP DAT)
Waste Disposal Methods: WHEN DISPOSING OF THE UNUSED CONTENTS, THE PREFERRED
OPTIONS ARE TO SEND TO A LICENSED RECLAIMER, OR TO PERMITTED INCINERATORS.
ANY DISPOSAL PRACTICE MUST BE IN ACCORDANCE WITH LOCAL, STATE, AND FEDER AL
LAWS AND REGULATIONS. CHECK WITH LOCAL AND STATE REGULATIONS BEFORE DUMPING
INTO SEWERS. DO NOT D UMP INTO ANY BODY OF WATER.
Handling And Storage Precautions: KEEP CONTAINER TIGHTLY CLOSED. STORE IN A
COOL DRY PLACE (2-8C). KEEP OUT OF REACH OF CHILDREN.
=======================================================
Fire and Explosion Hazard Information
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Extinguishing Media: NO RESTRICTIONS. USE EXTINGUISHING MEDIA APPROPRIATE TO
SURROUNDING FIRE CONDITIONS.
Fire Fighting Procedures: WEAR NIOSH APPROVED SELF-CONTAINED BREATHING
APPARATUS AND FULL PROTECTIVE EQUIPMENT (FP N). AVOID INHALATION OF TOXIC
FUMES. MOVE CONTAINER FROM FIRE AREA IF IT CAN BE DONE WITHOUT RISK.
Unusual Fire/Explosion Hazard: FLAMMABILITY (LIQUID): NON-FLAMMABLE. COMBUSTION
OR DECOMPOSITION OF MATERIAL MAY PRODUCE HAZARDOUS AND/OR IRRITATING FUMES.
HAZARDOUS POLYMERIZATION WILL NOT OCCUR.
=======================================================
Control Measures
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Respiratory Protection: AN APPROPRIATE NIOSH APPROVED RESPIRATOR IS RECOMMENDED
WHEN NUISANCE OR IRRITATING MISTS OR VAPORS ARE PRODUCED.
Ventilation: MECHANICAL EXHAUST IS REQUIRED.
Protective Gloves: CHEMICAL-RESISTANT GLOVES (RUBBER, PLASTIC).
Eye Protection: ANSI APPROVED CHEMICAL WORKERS GOGGLES (FP N).
Other Protective Equipment: ANSI APPROVED EMERGENCY EYEWASH AND DELUGE SHOWER
(FP N). WEAR APPROPRIATE PROTECTIVE CLOTHING.
Work Hygienic Practices: AVOID PHYSICAL CONTACT AND PROLONGED OR REPEATED
EXPOSURES. DO NOT GET IN EYES, ON SKIN, OR ON CLOTHING. WASH THOROUGHLY AFTER
HANDLING.
Supplemental Safety and Health: SPILL PROC: VENT AREA & WASH SPILL SITE
AFTER MATL PICKUP IS COMPLETE. REFER TO WASTE DISP METH SECTION FOR COMPLETE
DISP INFO.
=======================================================
Physical/Chemical Properties
=======================================================
Solubility in Water: SOLUBLE
Appearance and Odor: CLEAR AND COLORLESS LIQUID.
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Reactivity Data
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Stability Indicator: YES
Stability Condition To Avoid: NONE IDENTIFIED. STABLE WHEN USED APPROPRIATELY.
Materials To Avoid: NONE IDENTIFIED.
Hazardous Decomposition Products: CARBON MONOXIDE, CARBON DIOXIDE, NITROGEN
OXIDES.
Hazardous Polymerization Indicator: NO
=======================================================
Toxicological Information
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Toxicological Information: TOXICITY DATA: ORL-RAT LD50 (SODIUM CHLORIDE): 3000
MG/KG (IN PURE FORM). ORL-RAT LD50 (TRIZMA BASE): 5900 MG/KG (IN PURE FORM).
ORL-RAT LD50 (TWEEN 20): 3670 MG/KG (IN PURE FORM). ROUTES OF EXPOSURE:
INHALATION (LUNGS), INGESTION (GASTROINTESTINAL), SKIN (IN SOLUTION).
SHORT-TERM EFFECTS: MAY BE HARMFUL IF SWALLOWED, INHALED, OR ABSORBED THROUGH
THE SKIN. MATERIAL MAY BE IRRITATING TO THE EYES A ND SKIN. LONG-TERM
EFFECTS: NONE IDENTIFIED. TO THE BEST OF MANUFACTURER'S KNOWLEDGE, THE
CHEMICAL, PHYSICAL, AND TOXICOLOGICAL PROPERTIES OF THIS PRODUCT HAVE NOT
BEEN THOROUGHLY INVESTIGATED AT PROD UCT CONCENTRATIONS.
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Ecological Information
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MSDS Transport Information
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Regulatory Information
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Sara Title III Information: OTHER INFO: & CHEMS (HAZ INFO & PACKAGING
FOR SUPPLY) REGS 1994 (EUROPEAN COMMUNITY). THIS MSDS HAS BEEN PREPARED I/A/W
ANSI Z400.1-1993. REGULATORY EXCEPTIONS: 1) HAZ CLASSIFICATION (&
SUBSEQUENT R/S PHRASES/HAZ LABEL) IS NOT APPLIC WHEN CONC OF CHEM IN PROD IS
BELOW REPORTABLE "CONC LIMS" (88/379/EEC). 2) I/A/W DIRECTIVE 67/548/EEC,
ARTICLE 23, SECTION 3: "IN CASE OF IRRITANT, HIGHLY FLAMM, FLAM M &
OXIDIZING SUBSTANCES, AN INDICATION OF R-PHRASES & S-PHRASES NEED NOT BE
GIVEN WHERE PACKAGE DOES NOT CONTAIN MORE THAN 125 ML".
Federal Regulatory Information: HAZ SYMBOL: NOT REQUIRED. R-& S-PHRASES:
NONE REQUIRED. I/A/W EUROPEAN UNION DIRECTIVE 88/379/EEC, IT HAS BEEN
DETERMINED THAT CHEM COMPONENTS OF THIS PROD ARE CLASSIFIED AS HAVING NO
SIGNIFICANT HAZ, DUE TO PHYSICAL/CHEM NATURE &/OR CONCS OF INGS PRESENT.
RESTRICTIONS ON USE: PROD IS FOR LAB ONLY. PROD MUST NOT BE HANDLED BY PERS
UNDER 18 YRS OF AGE. TRAINING PROVISIONS: PROD SHOULD BE HANDLED ON LY BY
TECHNICALLY-QUALIFIED INDIVIDUALS EXPERIENCED IN HNDLG POTENTIALLY HAZ CHEMS.
CONTENTS OF THIS MSDS SHOULD ALSO BE KNOWN BEFORE USE. (OTHER INFO)
State Regulatory Information: CALIFORNIA PROPOSITION 65: THE FOLLOWING
STATEMENT IS MADE IN ORDER TO COMPLY WITH THE CALIFORNIA STATE DRINKING WATER
AND TOXIC ENFORCEMENT ACT OF 1986. THE PRODUCTS ON THIS MSDS DO NOT CONTAIN
CHEMI CALS ON CALIFORNIA'S LISTING OF KNOWN OR SUSPECTED CARCINOGENS.
=======================================================
Other Information
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Other Information: REC USE: THIS BUFFERED SALINE SOLN, AFTER DILUTION, IS
REQUIRED IN MANY IMMUNOHISTOCHEMICAL & IN SITU HYBRIDIZATION PROC.
SOURCES OF KEY DATA: MSDS FROM SUPPLIERS, SIGMA-ALDRICH LIBRARY OF CHEM SFTY,
MERCK INDEX, & SAX'S DANGEROUS PROPERTIES OF INDUS MATLS. FED REGS: OSHA
STATUS: I/A/W OSHA HAZ COMMUNICATION STD, AT PROD CONCS, CHEM COMPONENTS
LISTED ON THIS MSDS ARE CLASSIFIED AS HAVING NON SIGNI FICANT HAZ. TSCA: THIS
PROD COMPLIES W/ALL TSCA INVENTORY REQS. APPLIC COMPLIANCE STDS: THIS MSDS IS
IN COMPLIANCE W/FED OCCUP SFTY & HLTH ADMIN'S HAZ COMMUNICATION STD [29
CFR 1910.1200 ET. SEQ.], (S ARA REGS)
=======================================================
HAZCOM Label
=======================================================
MSDS NAME: TRIS-BUFFERED SALINE W/TWEEN 20 (TBST) 10X CONCENTRATE,S3306
Company: DAKO CORPORATION
Street: 6392 VIA REAL
City: CARPINTERIA CA
Zipcode: 93013
Health Emergency Phone: 805-566-6655
Label Required IND: Y
Date Of Label Review: 12/20/1999
Status Code: A
Origination Code: F
Eye Protection IND: YES
Skin Protection IND: YES
Signal Word: CAUTION
Respiratory Protection IND: YES
Health Hazard: Slight
Contact Hazard: Slight
Fire Hazard: None
Reactivity Hazard: None
Hazard And Precautions: ACUTE: MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN
ABSORPTION. MAY CAUSE IRRITATION. CHRONIC: NONE SPECIFIED BY MANUFACTURER
(FP N). TO THE BEST OF MANUFACTURER'S KNOWLEDGE, THE CHEMICAL, PHYSIC AL, AND
TOXICOLOGICAL PROPERTIES HAVE NOT BEEN THOROUGHLY INVESTIGATED.
=======================================================
Disclaimer (provided with this information by the compiling agencies): This
information is formulated for use by elements of the Department of Defense.
The United States of America in no manner whatsoever expressly or implied
warrants, states, or intends said information to have any application, use or
viability by or to any person or persons outside the Department of Defense
nor any person or persons contracting with any instrumentality of the United
States of America and disclaims all liability for such use. Any person
utilizing this instruction who is not a military or civilian employee of the
United States of America should seek competent professional advice to verify
and assume responsibility for the suitability of this information to their
particular situation regardless of similarity to a corresponding Department
of Defense or other government situation.
*** END OF RECORD *** |
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