===================== Product Identification =====================
MSDS NAME:03880 PIPRACIL STERILE PIPERACILLIN SODIUM 4 G/VIAL
NIIN:01-302-2668
MSDS Number: BWXWM
=== Responsible Party ===
Company:WYETH-AYERST LABORATORIES
Box:8299
City:PHILADELPHIA
State:PA
ZIP:19101-5000
Country:US
Info Phone Num:610-902-5171
Emergency Phone Num:610-902-5171
CAGE:0HMG4
=== Contractor Identification ===
Company:WYETH-AYERST LABORATORIES
Box:City:PHILADELPHIA
State:PA
ZIP:19101-5000
Country:US
Phone:610-902-5171
CAGE:0HMG4
============= Composition/Information on Ingredients =============
Name:SODIUM BICARBONATE
CAS:144-55-8
RTECS #:VZ0950000
Fraction by Wt: 2-4%
Name:PIPERACILLIN SODIUM, PENTCILLIN *95-1*
CAS:59703-84-3
RTECS #:XI0180000
Fraction by Wt: 96-98%
Name:PIPERACILLIN, T 1220
CAS:61477-96-1
RTECS #:XH8952200
===================== Hazards Identification =====================
LD50 LC50 Mixture:ORAL LD50 (RATS): >10 G/KG
Routes of Entry: Inhalation:YES Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:HAS THE CHARACTERISTICALLY LOW
POTENTIAL FOR TOXICITY FOUND W/OPTHER PENICILLIAN-TYPE ANTIBIOTICS.
CLINICALLY-OBSERVED SIDE EFFECTS THAT ARE SEEN INCLUDE ALLERGIC
REACTIONS. REVERSIBLE EFFECTS ON THE BLOOD, LIVER & KIDNEY FROM
PROLONGED/HIGH-DOSE CLINICAL USE.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:RASH, HIVES, SEVERE ITCHING, DIARRHEA, NAUSEA,
VOMITING, FEVER, HEADACHE, DIZZINESS, FATIGUE, LOCAL REDNESS,
ERYTHEMA, THROMBOPHLEBITIS.
Medical Cond Aggravated by Exposure:ALLERGIC REACTIONS TO ANY
PENICILLINS &/CEPHALOSPORINS.
======================= First Aid Measures =======================
Eyes: IMMEDIATELY FLUSH W/PLENTY OF COOL, LOW-PRESSURE WATER
FOR 20 MINS. SKIN: PROMPTLY WASH W/SOAP & COOL RUNNING WATER.
INHALATION: REMOVE TO FRESH AIR. GIVE CPR/OXYGEN IF NEEDED.
INGESTION: DON'T INDUCE VOMITING EXCEPT AS DIRECTED BY MEDICAL
PERSONNEL. NEVER GIVE ANYTHING BY MOUTH/INDUCE VOMITING IF
UNCONSCIOUS. OBTAIN MEDICAL ATTENTION IN ALL CASES.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR DISPOSABLE COVERALLS, RUBBER GLOVES & AN
APPROVED FULL FACE AIR-PURIFYING RESPIRATOR W/HIGH EFFICIENCY
CARTRIDGES/SELF CONTAINED/SUPPLIED AIR RESPIRATOR. CONTAIN &
COLLECT.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE AT CONTROLLED ROOM TEMP OF
59-86F. MINIMIZE EXCESS HANDLING. KEEP CONTAINER CLOSED WHEN NOT IN
USE.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:WEAR AN APPROVED AIR-PURIFYING RESPIRATOR
W/HIGH-EFFICIENCY CARTRIDGES ADEQUATE TO CONTROL EXPOSURE IF PEL IS
EXCEEDED.
Ventilation:USE CLOSED-SYSTEM HANDLING, LABORATORY BENCH HOOD/LOCAL
EXHAUST TO CONTROL DUST/MIST.
Protective Gloves:RUBBER
Eye Protection:REQUIRED
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING. REMOVE/LAUNDER
CONTAMINATED CLOTHING BEFORE REUSE.
Supplemental Safety and Health
INFORMATION IS FOR SODIUM BICARBONATE. PH: 5.5-7.5 (AQUEOUS SOLUTION OF
PIPRACIL).
================== Physical/Chemical Properties ==================
Decomp Temp:Decomp Text:518F (SUPP)
pH:(SUPP)
Solubility in Water:COMPLETE (SUPP)
Appearance and Odor:WHITE LYOPHILIZED CAKE.
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZERS/BASES.
Hazardous Decomposition Products:CO/CO2/NITROGEN
OXIDES/ALDEHYDES/KETONES/ORGANIC ACIDS/HYDROGEN CYANIDE/SULFUR
OXIDES/OTHER SULFUR CONTAINING COMPOUNDS.
==================== Disposal Considerations ====================
Waste Disposal Methods:DISPOSE OF IAW/FEDERAL, STATE & LOCAL
REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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