MSDS NAME:ACTIMMUNE
NIIN:01-352-2216
MSDS Number: BWXXK
=== Responsible Party ===
Company:GENENTECH INC
Address:460 POINT SAN BRUNO BLVD
City:SO SAN FRANCISCO
State:CA
ZIP:94080-5000
Country:US
Info Phone Num:415-266-1000/800-821-8590
Emergency Phone Num:415-266-1000/800-821-8590
CAGE:1HZ12
=== Contractor Identification ===
Company:GENENTECH INC
Address:460 PT. SAN BRUNO BLVD
Box:City:SOUTH SAN FRANSCISCO
State:CA
ZIP:94080
Country:US
Phone:415-266-1000/800-821-8590
CAGE:1HZ12
============= Composition/Information on Ingredients =============
Name:INTERFERON GAMMA-1B
Fraction by Wt: 0.02%
Name:MANNITOL *95-1*
CAS:87-78-1
RTECS #:OP2050000
Fraction by Wt: 3.8%
Name:SODIUM SUCCINATE HEXAHYDRIDE
Fraction by Wt: 0.07%
Routes of Entry: Inhalation:NO Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:TRANSIENT CUTANEOUS RASHES HAVE
OCCURED IN SOME PATIENTS FOLLOWING INJECTION. NO ADVERSE HEALTH
EFFECTS ARE EXPECTED.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:TRANSIENT CUTANEOUS RASHES HAVE OCCURRED IN
SOME PATIENTS FOLLOWING INJECTION. NO ADVERSE HEALTH EFFECTS.
======================= First Aid Measures =======================
First Aid:SKIN/EYES: FLUSH W/WATER. OBTAIN MEDICAL ATTENTION IN ALL
CASES.
Spill Release Procedures:CONTAIN W/ABSORBENT MATERIAL SUCH AS
VERMICULITE. WEAR PROTECTIVE GARMENTS AS APPLICABLE TO CLEANING UP
A NON HAZARDOUS LIQUID SPILL.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE AT 35.6-46.4F (UNDER
REFRIGERATION). HEAT WILL DEGRADE THE PROTEIN.
Respiratory Protection:NONE REQUIRED
Ventilation:NONE REQUIRED
Protective Gloves:NONE REQUIRED
Eye Protection:NONE REQUIRED
Other Protective Equipment:WEAR STANDARD LABORATORY/MANUFACTURING
PROTECTIVE GARMENTS.
Supplemental Safety and Health
RECOMBINANT HUMAN INTERFERON GAMMA-1B IS A THERAPEUTIC AGENT, WHICH IS
USED TO REDUCE THE FREQUENCY & SEVERITY OF SERIOUS INFECTIONS
ASSOCIATED W/CHRONIC GRANULOMATOUS DISEASE.
Waste Disposal Methods:DISPOSE OF IN ACCORDANCE W/LOCAL, STATE &
FEDERAL REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.