===================== Product Identification =====================
MSDS NAME:T8524 TRIZMA BASE MOLECULAR BIOLOGY REAGENT
NIIN:00-936-4996
MSDS Number: CFGTK
=== Responsible Party ===
Company:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:SAINT LOUIS
State:MO
ZIP:63178-5000
Country:US
Info Phone Num:314-771-5765/800-325-3010
Emergency Phone Num:314-771-5765/800-325-3010
CAGE:21076
=== Contractor Identification ===
Company:SIGMA CHEMICAL COMPANY
Address:3050 SPRUCE ST
Box:14508
City:ST LOUIS
State:MO
ZIP:63178
Country:US
Phone:314-771-5765
CAGE:21076
============= Composition/Information on Ingredients =============
Name:1,3-PROPANEDIOL , 2-AMINO-2-(HYDROXYMETHYL), TROMETHAMINE
CAS:77-86-1
RTECS #:TY2900000
===================== Hazards Identification =====================
LD50 LC50 Mixture:ORAL LD50(RAT): 5900 MG/KG
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:MAY BE HARMFUL BY INHALATION,
INGESTION/SKIN ABSORPTION. EYES/SKIN: IRRITATION. INHALATION:
IRRITATING TO MUCOUS MEMBRANES & UPPER RESPIRATORY TRACT.
Explanation of Carcinogenicity:NONE
Effects of Overexposure:IRRITATION.
======================= First Aid Measures =======================
First Aid:EYES/SKIN: FLUSH W/COPIOUS AMOUNTS OF WATER FOR 15 MINS.
INHALATION: REMOVE TO FRESH AIR. GIVE CPR/OXYGEN IF NEEDED.
INGESTION: WASH OUT MOUTH W/WATER IF CONSCIOUS. OBTAIN MEDICAL
ATTENTION IN ALL CAS ES.
===================== Fire Fighting Measures =====================
Extinguishing Media:WATER SPRAY, CO2, DRY CHEMICAL POWDER/APPROPRIATE
FOAM.
Fire Fighting Procedures:WEAR SCBA & PROTECTIVE CLOTHING.
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
================== Accidental Release Measures ==================
Spill Release Procedures:WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES,
RUBBER BOOTS & HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN A BAG & HOLD
FOR WASTE DISPOSAL. AVOID RAISING DUST. VENTILATE AREA & WASH SITE
AFTER MATERIAL PICKUP I S COMPLETE.
====================== Handling and Storage ======================
Handling and Storage Precautions:STORE IN A COOL DRY PLACE. KEEP
TIGHTLY CLOSED.
Other Precautions:AVOID PROLONGED/REPEATED EXPOSURE. AVOID CONTACT
W/EYES, SKIN/CLOTHING. DON'T BREATHE DUST.
============= Exposure Controls/Personal Protection =============
Respiratory Protection:USE NIOSH/MSHA APPROVED RESPIRATOR.
Ventilation:MECHANICAL EXHAUST REQUIRED.
Protective Gloves:COMPATIBLE CHEMICAL RESISTANT
Eye Protection:CHEMICAL SAFETY GOGGLES
Other Protective Equipment:SAFETY SHOWER & EYE BATH, PROTECTIVE
CLOTHING.
Work Hygienic Practices:REMOVE/LAUNDER CONTAMINATED CLOTHING & SHOES
BEFORE REUSE. WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
MELTING POINT: 340.16-342.14F.
================== Physical/Chemical Properties ==================
Boiling Pt:B.P. Text:426.2-428F
Melt/Freeze Pt:M.P/F.P Text:(SEE SUPP)
Appearance and Odor:WHITE CRYSTALS
================= Stability and Reactivity Data =================
Stability Indicator/Materials to Avoid:YES
BASES, OXIDIZING AGENTS.
Stability Condition to Avoid:MOISTURE.
Hazardous Decomposition Products:THERMAL COMBUSTION: CO, CO2, NITROGEN
OXIDES.
==================== Disposal Considerations ====================
Waste Disposal Methods:DISSOLVE/MIX W/A COMBUSTIBLE SOLVENT & BURN IN A
CHEMICAL INCINERATOR EQUIPPED W/AN AFTERBURNER & SCRUBBER,
IAW/FEDERAL, STATE & LOCAL REGULATIONS.
Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.
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