MSDS
EN
**** MATERIAL SAFETY DATA SHEET ****
Benzyl chloroformate, stabilized, 97wt%
**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****
MSDS Name: Benzyl chloroformate, stabilized, 97wt%
Catalog Numbers:
15294-0000, 15294-0050, 15294-1000
Synonyms:
Carbobenzoxy chloride, Carbonochloride acid benzylester
Company Identification (Europe): Acros Organics BVBA
Janssen Pharmaceuticalaan 3a
2440 Geel, Belgium
Company Identification (USA): Acros Organics
One Reagent Lane
Fairlawn, NJ 07410
For information in North America, call: 800-ACROS-01
For information in Europe, call: 0032(0) 14575211
For emergencies in the US, call CHEMTREC: 800-424-9300
For emergencies in Europe, call: 0032(0) 14575299
**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
| CAS# | Chemical Name | % | EINECS# |Haz Symbols| Risk Phrases |
|----------------|--------------------------------------|----------|-----------|-----------|---------------+
|----------------|--------------------------------------|----------|-----------|-----------|---------------|
| 100-44-7 |Benzylchloride | >0.1% | 202-853-6 |||
|----------------|--------------------------------------|----------|-----------|-----------|---------------|
| 501-53-1 |Benzyl chloroformate | 97 wt% | 207-925-0 |||
+----------------+--------------------------------------+----------+-----------+-----------+---------------+
Text for R-phrases: see Section 16
Hazard Symbols: T N
Risk Phrases: 34 45 20
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Causes burns. May cause cancer. Harmful by inhalation. Very toxic to
aquatic organisms, may cause long-term adverse effects in the aquatic
environment.Moisture sensitive.
Potential Health Effects
Eye:
Causes eye burns. Lachrymator (substance which increases the flow
of tears).
Skin:
Causes skin burns.
Ingestion:
Causes gastrointestinal tract burns.
Inhalation:
Causes respiratory tract irritation. Causes chemical burns to the
respiratory tract. Inhalation may be fatal as a result of spasm,
inflammation, edema of the larynx and bronchi, chemical pneumonitis
and pulmonary edema. May cause burning sensation, coughing, wheezing,
laryngitis, shortness of breath, headache, nausea, and vomiting.
Chronic:
May cause cancer in humans. May alter genetic material.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
http://newsearchfr2.chemexper.com/cheminfo/servlet/org....%3D%7E%3F%29&searchValue=501-53-1&options=brandqtyoffer (1 of 5)2008-5-6 21:59:12
MSDS
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
Treat symptomatically and supportively.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Will burn if involved in a fire. Containers may
explode in the heat of a fire.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Use foam, dry
chemical, or carbon dioxide. DO NOT USE WATER!
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Neutralize spill with sodium
bicarbonate. Isolate area and deny entry.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on
skin, or on clothing. Use only in a chemical fume hood.
Storage:
Keep away from sources of ignition. Store in a tightly closed
container. Store in a dry area. Keep refrigerated. (Store below
4鈥/39鈥.) Bottles should be vented periodically in order to
overcome pressure buildup.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Personal Protective Equipment
Eyes:
Wear chemical goggles.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Always use
http://newsearchfr2.chemexper.com/cheminfo/servlet/org....%3D%7E%3F%29&searchValue=501-53-1&options=brandqtyoffer (2 of 5)2008-5-6 21:59:12
MSDS
a NIOSH or European Standard EN 149 approved
respirator when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Clear liquid
Color: almost colorless
Odor: acrid odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 103 deg C @ 20 mmHg
Freezing/Melting Point: -20 deg C
Autoignition Temperature: Not available.
Flash Point: 91 deg C ( 195.80 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: > 50 deg C
Solubility in water: Reacts.
Specific Gravity/Density: 1.2 g/cm3
Molecular Formula: C8H7ClO2
Molecular Weight: 170.60
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Unstable.
Conditions to Avoid:
Incompatible materials, exposure to moist air or water, heat.
Incompatibilities with Other Materials:
Water, acids, bases, alcohols, amines.
Hazardous Decomposition Products:
Hydrogen chloride, phosgene, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 100-44-7: XS8925000
CAS# 501-53-1: LQ5860000
LD50/LC50:
CAS# 100-44-7: Inhalation, mouse: LC50 = 80 ppm/2H; Inhalation,
mouse: LC50 = 390 mg/m3/2H; Inhalation, rat: LC50 = 150 ppm/2H;
Inhalation, rat: LC50 = 740 mg/m3/2H; Oral, mouse: LD50 = 1500
mg/kg; Oral, rat: LD50 = 1231 mg/kg.
CAS# 501-53-1: Inhalation, rat: LC50 = 590 mg/m3/4H; Oral, rat: LD50
= 3 gm/kg.
Not available.
Carcinogenicity:
Benzylchloride -
ACGIH: A3 - Animal Carcinogen
California: carcinogen; initial date 1/1/90
OSHA: Possible Select carcinogen
IARC: Group 2A carcinogen
Benzyl chloroformate -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Other
Avoid entering into waters or underground water.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
http://newsearchfr2.chemexper.com/cheminfo/servlet/org....%3D%7E%3F%29&searchValue=501-53-1&options=brandqtyoffer (3 of 5)2008-5-6 21:59:12
MSDS
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: BENZYL CHLOROFORMATE (forbidden to ship via passen
ger aircraft). (forbidden to ship via passenger aircraft). (forbidden
Hazard Class: 8
UN Number: 1739
Packing Group: I
IMO
Shipping Name: BENZYL CHLOROFORMATE
Hazard Class: 8
UN Number: 1739
Packing Group: I
RID/ADR
Shipping Name: BENZYL CHLOROFORMATE
Hazard Class: 8
UN Number: 1739
Packing group: I
USA RQ:CAS# 100-44-7: 100 lb final RQ; 45.4 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 45 May cause cancer.
R 20 Harmful by inhalation.
R 34 Causes burns.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 100-44-7: 3
CAS# 501-53-1: No information available.
United Kingdom Occupational Exposure Limits
United Kingdom Maximum Exposure Limits
CAS# 100-44-7: MEL-United Kingdom, TWA 0.5 ppm TWA; 2.6 mg/m3 TWA
CAS# 100-44-7: MEL-United Kingdom, STEL 1.5 ppm STEL; 7.9 mg/m3 STEL
CAS# 100-44-7: MEL-United Kingdom, STEL 1.5 ppm STEL; 7.9 mg/m3 STEL
Canada
CAS# 100-44-7 is listed on Canada's DSL List.
CAS# 501-53-1 is listed on Canada's DSL List.
CAS# 100-44-7 is listed on Canada's Ingredient Disclosure List.
CAS# 501-53-1 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 100-44-7: OEL-AUSTRALIA:TWA 1 ppm (5 mg/m3)
OEL-AUSTRIA:TWA 1 ppm (5 mg/m3)
OEL-BELGIUM:TWA 1 ppm (5.2 mg/m3)
OEL-DENMARK:STEL 1 ppm (5 mg/m3)
OEL-DENMARK:TWA 1 ppm (5 mg/m3)
OEL-FINLAND:TWA 1 ppm (5 mg/m3);STEL 3 ppm (15 mg/m3)
http://newsearchfr2.chemexper.com/cheminfo/servlet/org....%3D%7E%3F%29&searchValue=501-53-1&options=brandqtyoffer (4 of 5)2008-5-6 21:59:12
MSDS
OEL-FRANCE:TWA 1 ppm (5 mg/m3);STEL 2 ppm (11 mg/m3);Skin
OEL-FRANCE:TWA 1 ppm (5 mg/m3);STEL 3 ppm (15 mg/m3);CAR
OEL-GERMANY:TWA 1 ppm (5 mg/m3);Carcinogen
OEL-HUNGARY:STEL 0.5 mg/m3;Skin
OEL-THE NETHERLANDS:TWA 1 ppm (5 mg/m3)
OEL-THE PHILIPPINES:TWA 1 ppm (5 mg/m3)
OEL-RUSSIA:STEL 0.5 mg/m3
OEL-SWEDEN:TWA 1 ppm (5 mg/m3);STEL 2 ppm (11 mg/m3)
OEL-SWEDEN:TWA 1 ppm (5 mg/m3);STEL 2 ppm (11 mg/m3);CAR
OEL-SWITZERLAND:TWA 1 ppm (5 mg/m3);STEL 2 ppm (1 mg/m3)
OEL-TURKEY:TWA 1 ppm (5 mg/m3)
OEL-UNITED KINGDOM:TWA 1 ppm (3 mg/m3);STEL 2 ppm (6 mg/m3)
OEL-UNITED KINGDOM:TWA 1 ppm (5 mg/m3)
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 100-44-7 is listed on the TSCA inventory.
CAS# 501-53-1 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 7/16/1996 Revision #3 Date: 3/05/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
http://newsearchfr2.chemexper.com/cheminfo/servlet/org....%3D%7E%3F%29&searchValue=501-53-1&options=brandqtyoffer (5 of 5)2008-5-6 21:59:12
|