PRODUCT: CAS NO:
Ingenol 3,20-dibenzoate 59086-90-7
CATALOG NO.: LOT NO.: P3420
PE-186
STRUCTURE:
H CH3
CH3
H3 C
O H
O H
O
HO H O
O
HO
O
PHYSICAL APPEARANCE: Colorless oil
MOLECULAR FORMULA: MOLECULAR WEIGHT: 556.7
C34H36O7
PURITY: 97%
SOLUBILITY: Soluble in ethanol (20 mg/ml) and DMSO (20 mg/ml)
STORAGE: Store, as supplied, at 鈥?20掳C for up to 1 year. Store
solutions at -20掳C for up to 3 months.
APPLICATION NOTES: Use Caution 鈥? product is a tumor promoter.
Diterpenoid related to phorbol. Competes with [3H]phorbol dibutyrate
for binding to PKC伪(Ki for binding = 240 nM). 1 The product is not
sterile.
REFERENCES: 1. J.D.Winkler et al. J.Org.Chem. 1995 60 1381
CAUTION!!! The pharmacological and toxicological properties of this product have not been fully
investigated. Avoid all forms of contact with this product by wearing appropriate protective
clothing (gloves, mask, lab coat). The Material Safety Data Sheet (MSDS), is available on request.
This product must not be used in humans
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