**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 100-00-5 |1-Chloro-4-nitrobenzene | 99 | 202-809-6 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T
Risk Phrases: 25 33 43
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic if swallowed. Danger of cumulative effects. May cause
sensitization by skin contact.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
Ingestion:
Harmful if swallowed. Aspiration of material into the lungs may
cause chemical pneumonitis, which may be fatal. Methemoglobinemia is
characterized by dizziness, drowsiness, headache, shortness of
breath, cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood), rapid heart rate and chocolate-brown
colored blood. May cause central nervous system depression.
Inhalation:
May cause effects similar to those described for ingestion.
Methemoglobinemia is characterized by dizziness, drowsiness,
headache, shortness of breath, cyanosis (bluish discoloration of skin
due to deficient oxygenation of the blood), rapid heart rate and
chocolate-brown blood.
Chronic:
May cause liver and kidney damage. Absorption into the body leads to
the formation of methemoglobin which in sufficient concentrations
causes cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood). May cause anemia and other blood cell
abnormalities. May cause fatigue, dizziness, headache, insomnia and
weight loss.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid immediately. Do NOT induce vomiting. If conscious and alert,
rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Do NOT use mouth-to-mouth
resuscitation.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene
Blue depending on the methemoglobin concentration in the blood.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool. Vapors may be heavier
than air. They can spread along the ground and collect in low or
confined areas. Containers may explode when heated.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Cool containers with flooding quantities of
water until well after fire is out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal. Avoid generating dusty conditions. Remove all sources of
ignition. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Avoid contact
with skin and eyes. Do not ingest or inhale.
Storage:
Store in a cool, dry place. Store in a cool, dry, well-ventilated
area away from incompatible substances. Keep containers tightly
closed.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.
Exposure Limits
CAS# 100-00-5:
United Kingdom, WEL - TWA: 1 mg/m3 TWA
United Kingdom, WEL - STEL: 2 mg/m3 STEL
United States OSHA: 1 mg/m3 TWA
Belgium - TWA: 0.1 ppm VLE; 0.65 mg/m3 VLE
Germany: 0.075 ppm TWA; 0.5 mg/m3 TWA
Germany: Skin absorber
Japan: 0.1 ppm OEL; 0.64 mg/m3 OEL
Malaysia: 0.1 ppm TWA; 0.64 mg/m3 TWA
Netherlands: 1 mg/m3 MAC
Russia: 1 mg/m3 TWA
Spain: 0.1 ppm VLA-ED; 0.65 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to
prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Crystals
Color: yellow
Odor: sweetish odor
pH: Not available.
Vapor Pressure: 0.019 mbar @ 20 deg C
Viscosity: Not available.
Boiling Point: 242 deg C @ 760 mm Hg
Freezing/Melting Point: 83 - 84 deg C
Autoignition Temperature: 510 deg C ( 950.00 deg F)
Flash Point: 127 deg C ( 260.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >300 deg C
Solubility in water: 0.3 G/L WATER (20C)
Specific Gravity/Density: 1.2980g/cm3
Molecular Formula: C6H4ClNO2
Molecular Weight: 157.56
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Ignition sources, dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 100-00-5: CZ1050000
LD50/LC50:
CAS# 100-00-5: Oral, mouse: LD50 = 440 mg/kg; Oral, rat: LD50 = 420
mg/kg; Skin, rabbit: LD50 = 3040 mg/kg; Skin, rat: LD50 = 16 gm/kg.
Carcinogenicity:
1-Chloro-4-nitrobenzene -
ACGIH: A3 - Confirmed animal carcinogen with unknown relevance to
California: carcinogen, initial date 10/29/99
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Other
No information available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: CHLORONITROBENZENES, SOLID
Hazard Class: 6.1
UN Number: 1578
Packing Group: II
IMO
Shipping Name: CHLORONITROBENZENES, SOLID
Hazard Class: 6.1
UN Number: 1578
Packing Group: II
RID/ADR
Shipping Name: CHLORONITROBENZENES
Hazard Class: 6.1
UN Number: 1578
Packing group: II
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T
Risk Phrases:
R 25 Toxic if swallowed.
R 33 Danger of cumulative effects.
R 43 May cause sensitization by skin contact.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 100-00-5: 2
Canada
CAS# 100-00-5 is listed on Canada's DSL List.
CAS# 100-00-5 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 100-00-5 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 12/14/1998 Revision #4 Date: 6/08/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
Tetrahydropyran-2-Methanol, 98%
| 100-72-1 |
|
Molecular sieves, 4a, 8 to 12 mesh
| 70955-01-0 |
|
1-Chloro-4-nitrobenzene, 99%
| 100-00-5 |
|
L-Strychnine, 98%
| 57-24-9 |
|
2-Nitrophenylacetic acid, 99%
| 3740-52-1 |
|
3-Chlorothiophene-2-carboxylic acid, 99+%
| 59337-89-2 |
|
4-Biphenylacetic acid, 98%
| 5728-52-9 |
|
N,N-Diethylnipecotamide, Tech.
| 3367-95-1 |
|
2-Hydroxy-5-methylbenzophenone
| 1470-57-1 |
|
2-Chloro-4-nitrobenzoic acid, 98%
| 99-60-5 |
|
3-(3-(Trifluoromethyl)Phenoxy)Benzaldehyde 97%
| 78725-46-9 |
|
Ethylenediaminetetraacetic acid, tetrasodium salt, hydrate , 99%
| 64-02-8 |
|
3,4-Dinitrobenzoic acid, 99%
| 528-45-0 |
|
Methyltrichlorosilane, 98%
| 75-79-6 |
|
2,2'-Dinitrobiphenyl, 97%
| 2436-96-6 |
|
Phosphoric acid-d3, 85 wt % solution in D2O, 99+ atom % D
| 14335-33-2 |
|
2-Amino-3-Hydroxypyridine, 98%
| 16867-03-1 |
|
1,2,3-Trichloropropane, 99+ %
| 96-18-4 |
|
2-(Ethylamino)-1,3,4-Thiadiazole
| 13275-68-8 |
|
Triethyl 2-phosphonopropionate, 98%
| 3699-66-9 |
|
1,2,3-Tribromo-5-Fluorobenzene, 99+%
| 3925-78-8 |
|
1-Methylimidazole, 99%
| 616-47-7 |
|
(r,r)-chiraphos, 97%
| 74839-84-2 |
|
1-Acetyl-1-cyclohexene, 97%
| 932-66-1 |
|
4-Nitroindole, 98%
| 4769-97-5 |
|
N,N-Dimethylacetamide Dimethyl Acetal, Tech., 85%
| 7732-18-5 |
|
Benzimidazole, 98%
| 51-17-2 |
|
DL-O-Methoxy-Alpha-Methylbenzyl Alcohol, 99%
| 13513-82-1 |
|
2,4-Dichloro-6-nitrophenol moist solid containing 20% water
| 609-89-2 |
|
3-Acetyl-n-tosylpyrrole, 99+%
| |
|
1-(Pyrrolidino)-1-cyclohexene, 97%
| 1125-99-1 |
|
4-Chlororesorcinol, 98%
| 95-88-5 |
|
P-(Methylthio)Benzyl Alcohol, 98%
| 3446-90-0 |
|
2-Hydroxy-gamma-butyrolactone, 99%
| 19444-84-9 |
|
Ethyl 4-Methoxycarbonylbenzoylacetate
| 79322-76-2 |
|
2,2,6-Trimethyl-4H-1,3-dioxin-4-one, 97% (GC)
| 67-64-1 |
|
L-(+)-Cysteine, 99+% (TLC)
| 52-90-4 |
|
2-Methoxy-1,3-Dioxolane, 99%
| 19693-75-5 |
|
Z-Alpha,Beta-Dinitrostilbene 99.5+%
| 1796-05-0 |
|
N-Acetylglycine, 99%
| 543-24-8 |
|
p-Toluenesulfonic acid sodium salt, 99% (titr.)
| 657-84-1 |
|
Acridine orange, 80% (uv-vis)
| 65-61-2 |
|
2,2-Dichlorooctadecanal, 90%
| 119450-47-4 |
|
p-Acetophenetidide, 97%
| 62-44-2 |
|
Rhodium on carbon (5% rh)
| |
|
1,2,4-Benzenetriamine Dihydrochloride (Pract), 99% (titr.)
| 615-47-4 |
|
Ammonium hexafluoroniobate(v), 99.99%
| 12062-13-4 |
|
Nylon 6/6
| 32131-17-2 |
|
Aluminum fluoride monohydrate, 99.999%,
| 7784-18-1 |
|
2,4-Dinitrotoluene, 95%, remainder 2,6-dinitrotoluene
| 121-14-2 |
|
|