**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 111-46-6 |Diethylene glycol | 100.0 | 203-872-2 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: 22
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful if swallowed.Hygroscopic.
Potential Health Effects
Eye:
May cause mild eye irritation.
Skin:
May cause mild skin irritation. May be absorbed through the skin.
Ingestion:
May cause liver and kidney damage. May cause central nervous system
depression, characterized by excitement, followed by headache,
dizziness, drowsiness, and nausea. Advanced stages may cause
collapse, unconsciousness, coma and possible death due to respiratory
failure. Human fatalities have been reported from acute poisoning.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Inhalation of heated or misted form may cause pulmonary edema.
Chronic:
Adverse reproductive effects have been reported in animals. A long
term rat feeding study showed that 1% diethylene glycol in the diet
over a 2-year period resulted in slight growth depression, a few
calcium oxalate bladder stones, minimal kidney damage, and
occasional liver damage. At 4% dietary level, there was increased
mortality, a marked depression of growth rate, bladder stones, severe
kidney damage, and moderate liver damage. In addition, bladder tumors
appeared rather frequently.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Immediately flush skin with plenty of soap and
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:
Treatment options include ipecac/lavage, activated charcoal,
cathartics--admisitered within two hours of ingestion. Hemodialysis
should be considered in severe intoxication.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Use water
spray to keep fire-exposed containers cool.
Extinguishing Media:
Water or foam may cause frothing. Alcohol foam, water fog, carbon
dioxide, dry chemical.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid
breathing vapors from heated material. Avoid contact with eyes, skin,
and clothing. Keep container tightly closed. Wash clothing before
reuse. Avoid breathing spray or mist.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible
substances. Keep containers tightly closed. Store protected from
moisture.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Good general ventilation should be sufficient to control airborne
levels.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR ??1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Viscous liquid
Appearance: colorless liquid
Odor: practically odorless
pH: Not available.
Vapor Pressure: 0.01 mm Hg @ 30 deg C
Viscosity: 0.30 cP @ 25 deg C
Boiling Point: 245 deg C
Freezing/Melting Point: -10 deg C
Autoignition Temperature: 224 deg C ( 435.20 deg F)
Flash Point: 124 deg C ( 255.20 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Soluble.
Specific Gravity/Density: 1.11
Molecular Formula: C4H10O3
Molecular Weight: 106.12
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 111-46-6: ID5950000
LD50/LC50:
CAS# 111-46-6: Draize test, rabbit, eye: 50 mg Mild; Draize test,
rabbit, skin: 500 mg Mild; Oral, mouse: LD50 = 23700 mg/kg; Oral,
rabbit: LD50 = 4400 mg/kg; Oral, rat: LD50 = 12565 mg/kg; Skin,
rabbit: LD50 = 11890 mg/kg.
Carcinogenicity:
Diethylene glycol -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish: Fathead Minnow: LC50 = >100.0 mg/L; 96 Hr.; Static
ConditionWater flea Daphnia: LC50 = 0.3-1.0 mg/L; 96 Hr.; Static
ConditionBacteria: Phytobacterium phosphoreum: EC50 = 228 mg/L; 15
minutes; Microtox test
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
No information available.
IMO
No information available.
RID/ADR
No information available.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
S 46 If swallowed, seek medical advice immediately
and show this container or label.
WGK (Water Danger/Protection)
CAS# 111-46-6: 1
United Kingdom Occupational Exposure Limits
CAS# 111-46-6: OES-United Kingdom, TWA 23 ppm TWA; 101 mg/m3 TWA
Canada
CAS# 111-46-6 is listed on Canada's DSL List.
CAS# 111-46-6 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 111-46-6: OEL-RUSSIA:STEL 10 mg/m3
OEL-UNITED KINGDOM:TWA 23 ppm (100 mg/m3)
US FEDERAL
TSCA
CAS# 111-46-6 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 6/08/1999 Revision #6 Date: 5/23/2002
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
3-Hydroxy-4-iodobenzoic acid, 97%
| 58123-77-6 |
|
Ethyl 1-cyclopropyl-4-formyl-2,5-dimethyl-1h-pyrrole-3-carboxylate,
| 423768-53-0 |
|
5-Chloro-3-methyl-1-benzothiophene-2-carboxylic acid, tech
| 50451-84-8 |
|
Tri-(2-Furyl)Phosphine, 98%
| 5518-52-5 |
|
4-[(4-Chlorophenyl)sulfonyl]-3-thiophenecarboxylic acid, 97%
| 423769-77-1 |
|
5-(Dihydroxyboryl)-2-thiophenecarboxylic acid, 95+%
| 465515-31-5 |
|
tert-Butyl n-[(5-bromo-2-thienyl)methyl]carbamate, 97%
| 215183-27-0 |
|
4-Acetyl-1-cyclopropyl-2,5-dimethyl-1h-pyrrole-3-carboxylic acid, 97%
| 423769-78-2 |
|
2-Bromo-1-[2-(trifluoromethyl)phenyl]-1-ethanone, 95+%
| 54109-16-9 |
|
Methyl 5-(chlorosulfonyl)-4-methyl-2-thiophenecarboxylate, 97%
| 423768-46-1 |
|
[5-[1-Methyl-5-(trifluoromethyl)-1h-pyrazol-3-yl]-2-thienyl]methanol,
| 465514-19-6 |
|
5-Nitro-1-benzothiophene-2-carboxylic acid, 97%
| 6345-55-7 |
|
Methyl 3-(chlorosulfonyl)-4-(isopropylsulf
| 423768-47-2 |
|
4-[4-(Trifluoromethyl)phenyl]-1,2,3-thiadiazol-5-amine, 97%
| 423769-76-0 |
|
Dl-alpha-bromophenylacetic acid, 99.5%
| 4870-65-9 |
|
Lead atomic absorption standard solution, 1 mg/ml Pb in 2% HNO3
| 7439-92-1 |
|
Methyl 5-formyl-2-methyl-3-furoate, 97%
| 81661-26-9 |
|
2-Bromo-1-[3-(trifluoromethyl)phenyl]-1-ethanone, tech
| 2003-10-3 |
|
Ethyl 4-acetyl-1-cyclopropyl-2,5-dimethyl-1h-pyrrole-3-carboxylate,
| 423768-51-8 |
|
3-(Aminomethyl)-N,N-dimethyltetrahydro-3-thiophenamine, 97%
| 176445-79-7 |
|
3-(2-Methyl-4-pyrimidinyl)benzenesulfonyl chloride, 90+%
| 465514-07-2 |
|
4-Bromo-1,3-dimethyl-1h-pyrazole-5-carboxylic acid, 97%
| 5775-88-2 |
|
3,5-Dimethyl-1-phenyl-1h-pyrazole-4-carboxylic acid, 97%
| 61226-19-5 |
|
Ethyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylate, 97%
| 22900-83-0 |
|
2-Bromo-4-methyl-1,3-thiazole-5-carboxylic acid, 97%
| 40003-41-6 |
|
2-Cyano-5-methylbenzenesulfonyl chloride, 97%
| 197960-31-9 |
|
3-Aminothieno[2,3-b]pyridine-2-carboxylic acid, 97%
| 58327-75-6 |
|
(S)-(-)-N,N-Dimethyl-1-Phenethylamine, 99+%
| 17279-31-1 |
|
[1-(4-Fluorophenyl)-5-methyl-1h-pyrazol-4-yl]methanol, 97%
| 465514-37-8 |
|
6-Chloro-imidazo[2,1-b]thiazole-5-sulfonic acid amide, 97%
| 112582-89-5 |
|
Ethyl 2-(chlorosulfonyl)-4-methyl-1,3-thiazole-5-carboxylate, 97%
| 89694-92-8 |
|
4-Methyl-thiazole-5-carboxylic acid, 97%
| 20485-41-0 |
|
2,3-Dihydroxy-benzoic acid ethyl ester, 97%
| 3943-73-5 |
|
Benzyl 4-hydroxytetrahydro-1(2h)-pyridinecarboxylate, 97+%
| 95798-23-5 |
|
Diethylene Glycol
| 111-46-6 |
|
2,3-Dihydro-1,4-benzodioxine-5-carboxamide, 97%
| 349550-81-8 |
|
1H-Benzimidazol-4-ylboronic acid, 97%
| 499769-95-8 |
|
4-Iodo-2-methyl-1h-imidazole, 97%
| 73746-45-9 |
|
1-Benzyl-1h-indol-5-ylamine, 97%
| 26807-73-8 |
|
1,3-Dinitrobenzene
| 99-65-0 |
|
3-(Benzyloxy)-4-methylphenylamine, 97%
| 219492-12-3 |
|
5-(Benzyloxy)-2-bromo-4-methylaniline, 97%
| 499770-88-6 |
|
4-(Bromomethyl)-1-methyl-1,2,3,6-tetrahydropyridine, 97%
| 499770-89-7 |
|
Bis(2-methoxyethyl) Ether
| 111-96-6 |
|
2,6-Dichloro-4-(chloromethyl)pyridine, tech
| 101990-72-1 |
|
4-(Benzyloxy)-3-fluorophenylboronic acid, 97%
| 133057-83-7 |
|
4-(Benzyloxy)-2-fluorophenylboronic acid, 97%
| 166744-78-1 |
|
5-Cyano-2-thienylboronic acid, 97%
| 305832-67-1 |
|
Alpha, Alpha, Alpha-Trifluoro-P-Tolualdehyde, 95%
| 455-19-6 |
|
5-(Methylsulfanyl)-2-thienylboronic acid, 97%
| 499769-93-6 |
|
|