**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 1712-64-7 |Isopropyl Nitrate | ca 100 | 216-983-6 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: O F
Risk Phrases: 11 8
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Highly flammable. Contact with combustible material may cause fire.
Potential Health Effects
Eye:
May cause permanent corneal opacification. May cause chemical
conjunctivitis and corneal damage.
Skin:
May cause severe irritation and possible burns. May cause irritation
and dermatitis. May cause cyanosis of the extremities.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea. Methemoglobinemia is characterized by dizziness,
drowsiness, headache, shortness of breath, cyanosis (bluish
discoloration of skin due to deficient oxygenation of the blood),
rapid heart rate and chocolate-brown colored blood. May cause burns
to the gastrointestinal tract. Ingestion of large amounts may cause
CNS depression. Ingestion of nitrate containing compounds can lead to
methemoglobinemia. May cause nausea, vomiting, and diarrhea, possibly
with blood.
Inhalation:
Aspiration may lead to pulmonary edema. Methemoglobinemia is
characterized by dizziness, drowsiness, headache, shortness of
breath, cyanosis (bluish discoloration of skin due to deficient
oxygenation of the blood), rapid heart rate and chocolate-brown
blood. Vapors may cause dizziness or suffocation. May cause burning
sensation in the chest. May cause acute pulmonary edema, asphyxia,
chemical pneumonitis, and upper airway obstruction caused by edema.
Chronic:
May cause methemoglobinemia, which is characterized by
chocolate-brown colored blood, headache, weakness, dizziness, breath
shortness, cyanosis (bluish skin due to deficient oxygenation of
blood), rapid heart rate, unconsciousness and possible death.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid. Do
NOT allow victim to rub eyes or keep eyes closed.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene
Blue depending on the methemoglobin concentration in the blood. Treat
symptomatically and supportively.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. Strong
oxidizer. Contact with other material may cause fire. During a fire,
irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed
containers cool. Use water with caution and in flooding amounts.
Water may be ineffective. Material is lighter than water and a fire
may be spread by the use of water. Containers may explode in the heat
of a fire. Flammable liquid and vapor. Vapors may be heavier than
air. They can spread along the ground and collect in low or confined
areas. May polymerize explosively when involved in a fire. Runoff to
sewer may create fire or explosion hazard.
Extinguishing Media:
Use water spray to cool fire-exposed containers. Water may be
ineffective. Do NOT use straight streams of water. For small fires,
use dry chemical, carbon dioxide, water spray or regular foam.
Contact professional fire-fighters immediately. For large fires, use
water spray, fog or regular foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. A vapor suppressing foam
may be used to reduce vapors.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Ground and bond
containers when transferring material. Use spark-proof tools and
explosion proof equipment. Empty containers retain product residue,
(liquid and/or vapor), and can be dangerous. Keep away from heat,
sparks and flame. Avoid contact with clothing and other combustible
materials. Do not get on skin or in eyes. Avoid ingestion and
inhalation. Do not pressurize, cut, weld, braze, solder, drill,
grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Do not store near combustible materials. Store in a cool,
dry place. Keep container closed when not in use. Flammables-area.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to
acceptable levels.
Exposure Limits
CAS# 1712-64-7:
Germany: 45 mg/m3 TWA
Russia: 5 mg/m3 TWA
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear a chemical apron. Wear appropriate clothing to
prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 98.0 - 102.0 deg C
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: 11.1 deg C ( 51.98 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.0360g/cm3
Molecular Formula: C3H7NO3
Molecular Weight: 105.09
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, combustible
materials, reducing agents, strong oxidants.
Incompatibilities with Other Materials:
Reducing agents, finely powdered metals, strong acids.
Hazardous Decomposition Products:
Carbon monoxide, oxides of nitrogen, irritating and toxic fumes and
gases, carbon dioxide.
Hazardous Polymerization: Has not been reported
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 1712-64-7: QU8930000
LD50/LC50:
CAS# 1712-64-7: Inhalation, mouse: LC50 = 65 gm/m3/2H; Inhalation,
rat: LC50 = 29 gm/m3/2H.
Carcinogenicity:
Isopropyl Nitrate -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ISOPROPYL NITRATE
Hazard Class: 3
UN Number: 1222
Packing Group: II
IMO
Shipping Name: ISOPROPYL NITRATE
Hazard Class: 3.2
UN Number: 1222
Packing Group: II
RID/ADR
Shipping Name: ISOPROPYL NITRATE
Hazard Class: 3
UN Number: 1222
Packing group: II
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: O F
Risk Phrases:
R 11 Highly flammable.
R 8 Contact with combustible material may cause
fire.
Safety Phrases:
S 9 Keep container in a well-ventilated place.
S 16 Keep away from sources of ignition - No
smoking.
S 33 Take precautionary measures against static
discharges.
WGK (Water Danger/Protection)
CAS# 1712-64-7: No information available.
Canada
CAS# 1712-64-7 is listed on Canada's NDSL List.
CAS# 1712-64-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 1712-64-7 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 7/15/1999 Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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