**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 54-11-5 |Nicotine | 95% | 200-193-3 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+ N
Risk Phrases: 25 27 51/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic if swallowed. Very toxic in contact with skin. Toxic to
aquatic organisms, may cause long-term adverse effects in the
aquatic environment.Hygroscopic (absorbs moisture from the air).
Potential Health Effects
Eye:
Causes eye irritation. Causes redness and pain.
Skin:
Causes skin irritation. May be fatal if absorbed through the skin.
May cause dermatitis.
Ingestion:
Poison by ingestion. May cause adverse effects of the musculature.
May cause severe digestive tract irritation with abdominal pain,
nausea, vomiting and diarrhea. May cause tremors and convulsions.
May cause muscle paralysis, respiratory failure, and possible death.
Inhalation:
May cause effects similar to those described for ingestion.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. May cause
digestive tract and cardiac disturbances. Prolonged or repeated
exposure may cause nausea, dizziness, and headache.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists. Discard contaminated clothing in a
manner which limits further exposure. Destroy contaminated shoes.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Can form explosive mixtures at temperatures above
the flashpoint.
Extinguishing Media:
For small fires, use water spray, dry chemical, carbon dioxide or
chemical foam. Water or foam may cause frothing.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Wear a self contained breathing apparatus and appropriate personal
protection. (See Exposure Controls, Personal Protection section).
Remove all sources of ignition. Absorb spill using an absorbent,
non-combustible material such as earth, sand, or vermiculite. Do not
use combustible materials such as sawdust.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Ground and bond
containers when transferring material. Use spark-proof tools and
explosion proof equipment. Do not reuse this container. Do not get
on skin or in eyes. Do not ingest or inhale. Use only in a chemical
fume hood.
Storage:
Keep away from sources of ignition. Keep under a nitrogen blanket.
Keep from contact with oxidizing materials. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep away
from strong acids. Poison room locked.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 54-11-5:
United Kingdom, WEL - TWA: 0.5 mg/m3 TWA
United Kingdom, WEL - STEL: 1.5 ppm STEL
United States OSHA: 0.5 mg/m3 TWA
Belgium - TWA: 0.5 mg/m3 VLE
France - VME: 0.5 mg/m3 VME
Germany: 0.07 ppm TWA; 0.47 mg/m3 TWA
Germany: Skin absorber
Malaysia: 0.5 mg/m3 TWA
Netherlands: 0.07 ppm MAC; 0.5 mg/m3 MAC
Spain: 0.5 mg/m3 VLA-ED
Personal Protective Equipment
Eyes:
Not available.
Skin:
Wear impervious gloves.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Clear liquid
Color: brown
Odor: fish-like - weak odor
pH: Not available.
Vapor Pressure: 1.3 mbar @ 62 deg C
Viscosity: Not available.
Boiling Point: 247 deg C @ 760.00M
Freezing/Melting Point: -80 deg C
Autoignition Temperature: 240 deg C ( 464.00 deg F)
Flash Point: 101 deg C ( 213.80 deg F)
Explosion Limits, lower: .70 vol %
Explosion Limits, upper: 4.00 vol %
Decomposition Temperature:
Solubility in water: IN WATER: MISCIBLE BELOW 60C
Specific Gravity/Density: 1.0100g/cm3
Molecular Formula:
Molecular Weight: 162.23
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable at normal temperatures in tightly closed containers under an
inert atmosphere. Substance undergoes color change upon exposure to
light and air.
Conditions to Avoid:
Incompatible materials, light, exposure to air, exposure to moist air
or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, strong bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 54-11-5: QS5250000
LD50/LC50:
CAS# 54-11-5: Oral, mouse: LD50 = 3340 ug/kg; Oral, rat: LD50 = 50
mg/kg; Skin, rabbit: LD50 = 50 mg/kg; Skin, rat: LD50 = 140 mg/kg.
Carcinogenicity:
Nicotine -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Fish (fresh water) 3-29ppm toxic (time period not specified).
LC50
(96hr) rainbow trout ~ 4 mg/l (Edsall, C.C. Bull. Environ. Contam.
Toxicol. 1991, 46, 173-188).
Trout, bluegill sunfish 5 ppm caused
death within 22, 7 hr respectively. 5 ppm (24 hr) goldfish no effect
was observed (The Toxicity of 3400 Chemicals to Fish 1987,
EPA560/6-87-002, PB87-200-275, Washington DC
Steel trout, bridge
sucker 2 mg/l caused death within 2 hr of exposure (Lethal Effects
of 2014 Chemicals to Fish 1989, EPA 560/6-89-001, PB 89-156715,
Washington DC).
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: NICOTINE
Hazard Class: 6.1
UN Number: 1654
Packing Group: II
IMO
Shipping Name: NICOTINE
Hazard Class: 6.1
UN Number: 1654
Packing Group: II
RID/ADR
Shipping Name: NICOTINE
Hazard Class: 6.1
UN Number: 1654
Packing group: II
USA RQ: CAS# 54-11-5: 100 lb final RQ; 45.4 kg final RQ
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 25 Toxic if swallowed.
R 27 Very toxic in contact with skin.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 54-11-5: No information available.
Canada
CAS# 54-11-5 is listed on Canada's DSL List.
CAS# 54-11-5 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 54-11-5 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 7/03/2000 Revision #1 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
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