**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 6283-25-6 |2-Chloro-5-Nitroaniline | 99 | 228-498-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+ N
Risk Phrases: 26/27/28 33 51/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Danger of cumulative effects. Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.The
toxicological properties of this material have not been fully
investigated.Dangerous for the environment.
Potential Health Effects
Eye:
May cause eye irritation. The toxicological properties of this
material have not been fully investigated.
Skin:
May cause skin irritation. The toxicological properties of this
material have not been fully investigated.
Ingestion:
May cause irritation of the digestive tract. The toxicological
properties of this substance have not been fully investigated.
Methemoglobinemia is characterized by dizziness, drowsiness,
headache, shortness of breath, cyanosis (bluish discoloration of skin
due to deficient oxygenation of the blood), rapid heart rate and
chocolate-brown colored blood. May form methemoglobin which in
sufficient concentration causes cyanosis (bluish discoloration of
skin due to deficient oxygenation of the blood).
Inhalation:
May cause respiratory tract irritation. The toxicological properties
of this substance have not been fully investigated. Inhalation of
aniline causes anoxia due to the formation of methemoglobin.
Chronic:
No information found. Absorption into the body leads to the
formation of methemoglobin which in sufficient concentrations causes
cyanosis (bluish discoloration of skin due to deficient oxygenation
of the blood).
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical
aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and
drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
For methemoglobinemia, administer oxygen alone or with Methylene
Blue depending on the methemoglobin concentration in the blood.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry
chemical, carbon dioxide, or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective
Equipment section. Sweep up, then place into a suitable container for
disposal. Avoid generating dusty conditions. Remove all sources of
ignition. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid
contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 6283-25-6:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: dark yellow
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Decomposes
Freezing/Melting Point: 116 - 121 deg C
Autoignition Temperature: 320 deg C ( 608.00 deg F)
Flash Point: 200 deg C ( 392.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 320 deg C
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C6H5ClN2O2
Molecular Weight: 172.57
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, ignition sources, dust generation, excess
heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 6283-25-6: BX1500000
LD50/LC50:
CAS# 6283-25-6: Oral, mouse: LD50 = 1600 mg/kg; Oral, rat: LD50 =
2015 mg/kg.
Not available.
Carcinogenicity:
2-Chloro-5-Nitroaniline -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: CHLORONITROANILINES
Hazard Class: 6.1
UN Number: 2237
Packing Group: III
IMO
Shipping Name: CHLORONITROANILINES
Hazard Class: 6.1
UN Number: 2237
Packing Group: III
RID/ADR
Shipping Name: CHLORONITROANILINES
Hazard Class: 6.1
UN Number: 2237
Packing group: III
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 33 Danger of cumulative effects.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 6283-25-6: 2
Canada
CAS# 6283-25-6 is listed on Canada's NDSL List.
CAS# 6283-25-6 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 6283-25-6 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 12/14/1998 Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
4-Aminoantipyrine Hydrochloride, 99% (Titr.)
| 22198-72-7 |
|
n-Phenylmaleimide, 97%
| 941-69-5 |
|
(R)-(-)-3-Quinuclidinol, 99+% (GC)
| 25333-42-0 |
|
(+)-N-Methylephedrine, 98%
| 42151-56-4 |
|
4-Methoxy-3-pyrrolin-2-one, 99+%
| 69778-83-2 |
|
5-Iodouracil, 99%
| 696-07-1 |
|
2,2-Dimethyl-6,6,7,7,8,8,8-Heptafluoro-3,5-Octanedione, 98%
| 17587-22-3 |
|
Chloromethyl pivalate, 99+%
| 18997-19-8 |
|
18-Crown-6 Acetonitrile Complex, Mole Ratio 2.0 +/-0.2 to 1.0
| 55075-35-9 |
|
9-Cyanophenanthrene
| 2510-55-6 |
|
Isobutyramide, 99%
| 563-83-7 |
|
Ethyl (2S,3S)-2,3-epoxy-3-methylpropanoate 99%
| 110508-08-2 |
|
Butyl pbd, scintillation grade
| 15082-28-7 |
|
N-Alpha-Benzoyl-L-Arginine Amide Hydrochloride Monohydrate, 99%
| 965-03-7 |
|
2,4-Dinitrodiphenylamine, 98%
| 961-68-2 |
|
Methyl tetrahydrofurfuryl ether
| 19354-27-9 |
|
2,2,5,5-Tetramethyl-4-Phenacetyliden Imidazolidine-1-Oxyl, Free
| 84271-26-1 |
|
Gramine, 99%
| 87-52-5 |
|
Cyanoacetohydrazide, 98%
| 140-87-4 |
|
(1r,2s)-1-carboxy-1,2-dihydroxycyclohexa- 3,5-diene, 95%
| 100459-00-5 |
|
l(+)-Isoleucinol, 97%
| 24629-25-2 |
|
4-(Diethylamino)benzoic Acid, 99%
| 5429-28-7 |
|
5'-Tosyladenosine, 99+%
| 5135-30-8 |
|
3-Fluorobenzyl chloride, 96%
| 456-42-8 |
|
2-Chloro-4-Fluorobenzylalcohol
| |
|
Normal-Butyronitrile, P.A.
| 109-74-0 |
|
Dicyclopentamethylenethiuram Disulfide 99+%
| 94-37-1 |
|
DL-2-Phenylpropionic Acid, 98%
| 492-37-5 |
|
n-Acetyl-5-hydroxytryptamine
| 17994-17-1 |
|
1-Ethylquinolinium Iodide
| 634-35-5 |
|
Tragacanth, Powder
| 9000-65-1 |
|
Perfluoro-compound FC-40
| 51142-49-5 |
|
2-Chloro-5-Nitroaniline, 99%
| 6283-25-6 |
|
2-Diphenylacetyl-1,3-Indandione-1-Hydrazone, 98%
| 5102-79-4 |
|
Naphthenic acids sodium salts (pract)
| 61790-13-4 |
|
p-Phenylenediamine dihydrochloride, 99+%
| 624-18-0 |
|
Thymolphthalein monophosphoric acid, disodium salt
| 28749-63-5 |
|
O-Cresolphtalein Complexone Sodium Salt
| 62698-54-8 |
|
Ytterbium(III) Chloride Hexahydrate, 99.999%
| 10035-01-5 |
|
2-Methyl-4-nitroaniline, 99%
| 99-52-5 |
|
2,4,6-Collidine, tech., 75%
| 108-75-8 |
|
Ethyl 2-chloropropionate, 97%
| 535-13-7 |
|
4-Cyanobenzaldehyde, 98%
| 105-07-7 |
|
2-Coumaranone, 97%
| 553-86-6 |
|
beta-Glycerophosphoric acid disodium salt, pentahydrate, 98% (Titr.)
| 819-83-0 |
|
2,2,2-Trichloroethyl chloroformate, 98% (titr.)
| 17341-93-4 |
|
DL-Alpha-Hydroxyisocaproic Acid, 99%
| 10303-64-7 |
|
(Ethanediylidenetetrathio)tetraacetic acid, 99%
| 10003-69-7 |
|
Cyclopentane, spectr. grade, 75% cyclopent ane, balance sat. c 5
| 287-92-3 |
|
2-Thiophenemethanol, 99+%
| 636-72-6 |
|
|