**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 99-52-5 |2-Methyl-4-nitroaniline | 99 | 202-762-1 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T N
Risk Phrases: 23/24/25 33 51/53
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed. Danger
of cumulative effects. Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. Harmful if absorbed through the skin.
Ingestion:
Harmful if swallowed. Causes gastrointestinal tract irritation.
Inhalation:
Causes respiratory tract irritation.
Chronic:
May cause methemoglobinemia, which is characterized by
chocolate-brown colored blood, headache, weakness, dizziness, breath
shortness, cyanosis (bluish skin due to deficient oxygenation of
blood), rapid heart rate, unconsciousness and possible death.
Laboratory experiments have resulted in mutagenic effects.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical
aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Treat symptomatically and supportively.
Antidote:
Methylene blue, alone or in combination with oxygen is indicated as
a treatment in nitrite induced methemoglobinemia.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Water runoff can cause environmental damage. Dike
and collect water used to fight fire. During a fire, irritating and
highly toxic gases may be generated by thermal decomposition or
combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. In case of fire, use
carbon dioxide, dry chemical powder or appropriate foam.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Avoid
generating dusty conditions. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Do not get in eyes, on skin, or on
clothing. Do not ingest or inhale.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 99-52-5:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR 1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant respirator use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Powder
Color: yellow
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 131-133 deg C
Autoignition Temperature: Not available.
Flash Point: 300 deg C ( 572.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: 300 deg C
Solubility in water: Insoluble.
Specific Gravity/Density:
Molecular Formula: C7H8N2O2
Molecular Weight: 152.15
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, strong oxidants.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides, acid anhydrides,
chloroformates.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 99-52-5: XU8210000
LD50/LC50:
Not available.
CAS #: 62-53-3 Oral, rat: LD50 = 250 mg/kg.; Dermal, rabbit: LD50 =
820 uL/kg. The toxicity of this product was partially based on the
hazards associated with
Carcinogenicity:
2-Methyl-4-nitroaniline -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
This data is based on 2-Methyl-5-nitroanailine. Estimated BCF value =
1.96. This value suggests that bioconcentration in aquatic organisms
would not be significant. Estimated Koc value = 277. The Koc value
suggests that 2-Methyl-5-nitroaniline would be moderately mobile in
soil. Adsorption to suspended solids and sediments in water and loss
of mobility in soil may result from bonding with humates.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: NITROTOLUIDINES (MONO)
Hazard Class: 6.1
UN Number: 2660
Packing Group: III
IMO
Shipping Name: NITROTOLUIDINES
Hazard Class: 6.1
UN Number: 2660
Packing Group: III
RID/ADR
Shipping Name: NITROTOLUIDINES (MONO)
Hazard Class: 6.1
UN Number: 2660
Packing group: III
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T N
Risk Phrases:
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 33 Danger of cumulative effects.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 99-52-5: 2
Canada
CAS# 99-52-5 is listed on Canada's NDSL List.
CAS# 99-52-5 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 99-52-5 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 2/03/1999 Revision #2 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
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(R)-(-)-3-Quinuclidinol, 99+% (GC)
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(+)-N-Methylephedrine, 98%
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4-Methoxy-3-pyrrolin-2-one, 99+%
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5-Iodouracil, 99%
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2,2-Dimethyl-6,6,7,7,8,8,8-Heptafluoro-3,5-Octanedione, 98%
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Chloromethyl pivalate, 99+%
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18-Crown-6 Acetonitrile Complex, Mole Ratio 2.0 +/-0.2 to 1.0
| 55075-35-9 |
|
9-Cyanophenanthrene
| 2510-55-6 |
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Ethyl (2S,3S)-2,3-epoxy-3-methylpropanoate 99%
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Butyl pbd, scintillation grade
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N-Alpha-Benzoyl-L-Arginine Amide Hydrochloride Monohydrate, 99%
| 965-03-7 |
|
2,4-Dinitrodiphenylamine, 98%
| 961-68-2 |
|
Methyl tetrahydrofurfuryl ether
| 19354-27-9 |
|
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| 84271-26-1 |
|
Gramine, 99%
| 87-52-5 |
|
Cyanoacetohydrazide, 98%
| 140-87-4 |
|
(1r,2s)-1-carboxy-1,2-dihydroxycyclohexa- 3,5-diene, 95%
| 100459-00-5 |
|
l(+)-Isoleucinol, 97%
| 24629-25-2 |
|
4-(Diethylamino)benzoic Acid, 99%
| 5429-28-7 |
|
5'-Tosyladenosine, 99+%
| 5135-30-8 |
|
3-Fluorobenzyl chloride, 96%
| 456-42-8 |
|
2-Chloro-4-Fluorobenzylalcohol
| |
|
Normal-Butyronitrile, P.A.
| 109-74-0 |
|
Dicyclopentamethylenethiuram Disulfide 99+%
| 94-37-1 |
|
DL-2-Phenylpropionic Acid, 98%
| 492-37-5 |
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n-Acetyl-5-hydroxytryptamine
| 17994-17-1 |
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| 634-35-5 |
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Tragacanth, Powder
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Perfluoro-compound FC-40
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| 6283-25-6 |
|
2-Diphenylacetyl-1,3-Indandione-1-Hydrazone, 98%
| 5102-79-4 |
|
Naphthenic acids sodium salts (pract)
| 61790-13-4 |
|
p-Phenylenediamine dihydrochloride, 99+%
| 624-18-0 |
|
Thymolphthalein monophosphoric acid, disodium salt
| 28749-63-5 |
|
O-Cresolphtalein Complexone Sodium Salt
| 62698-54-8 |
|
Ytterbium(III) Chloride Hexahydrate, 99.999%
| 10035-01-5 |
|
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| 99-52-5 |
|
2,4,6-Collidine, tech., 75%
| 108-75-8 |
|
Ethyl 2-chloropropionate, 97%
| 535-13-7 |
|
4-Cyanobenzaldehyde, 98%
| 105-07-7 |
|
2-Coumaranone, 97%
| 553-86-6 |
|
beta-Glycerophosphoric acid disodium salt, pentahydrate, 98% (Titr.)
| 819-83-0 |
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DL-Alpha-Hydroxyisocaproic Acid, 99%
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| 10003-69-7 |
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Cyclopentane, spectr. grade, 75% cyclopent ane, balance sat. c 5
| 287-92-3 |
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2-Thiophenemethanol, 99+%
| 636-72-6 |
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|