**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 66-81-9 |Cycloheximide | >95 | 200-636-0 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+ N
Risk Phrases: 28 61 51/53 68
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Very toxic if swallowed. May cause harm to the unborn child. Toxic
to aquatic organisms, may cause long-term adverse effects in the
aquatic environment.Possible risk of irreversible effects.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
Ingestion:
May be fatal if swallowed.
Inhalation:
Causes respiratory tract irritation.
Chronic:
Repeated exposure may cause sensitization dermatitis. May cause
reproductive and fetal effects.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Ingestion:
POISON material. If swallowed, get medical aid immediately. Only
induce vomiting if directed to do so by medical personnel. Never give
anything by mouth to an unconscious person.
Inhalation:
Get medical aid immediately. Remove from exposure and move to fresh
air immediately. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Do NOT use mouth-to-mouth
resuscitation.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Vapors may
be heavier than air. They can spread along the ground and collect
in low or confined areas.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal
container. Reduce airborne dust and prevent scattering by moistening
with water. Clean up spills immediately, observing precautions in
the Protective Equipment section. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Wash hands before eating. Remove
contaminated clothing and wash before reuse. Minimize dust generation
and accumulation. Do not get on skin or in eyes. Do not ingest or
inhale. Use only in a chemical fume hood.
Storage:
Store in a cool, dry place. Store in a tightly closed container.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Exposure Limits
CAS# 66-81-9:
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Crystalline powder
Color: white to beige
Odor: odorless
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 107-114 deg C
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: Slightly soluble in water.
Specific Gravity/Density: Not available.
Molecular Formula: C15H23NO4
Molecular Weight: 281.35
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Dust generation, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases, acid chlorides, acid
anhydrides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 66-81-9: MA4375000
LD50/LC50:
CAS# 66-81-9: Draize test, rabbit, skin: 1 pph/24H Moderate; Oral,
mouse: LD50 = 133 mg/kg; Oral, rat: LD50 = 2 mg/kg.
Carcinogenicity:
Cycloheximide -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.*
Hazard Class: 6.1
UN Number: 2811
Packing Group: I
IMO
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing Group: I
RID/ADR
Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.
Hazard Class: 6.1
UN Number: 2811
Packing group: I
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 61 May cause harm to the unborn child.
R 28 Very toxic if swallowed.
R 51/53 Toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
R 68 Possible risk of irreversible effects.
Safety Phrases:
S 53 Avoid exposure - obtain special instructions
before use.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 66-81-9: 3
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 66-81-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 66-81-9 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 10/15/1998 Revision #5 Date: 6/24/2004
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
L-Carnosine, 98%
| 305-84-0 |
|
Ethylbenzene-d10, 98+ atom % d
| 25837-05-2 |
|
Molybdenyl acetylacetonate, 99%
| 17524-05-9 |
|
3,7-Dimethyl-7-Hydroxyoctanal, 98%
| 107-75-5 |
|
D-L-5-Fluorotryptophan, 99+%
| 154-08-5 |
|
6-Chloronicotinic Acid, 99%
| 5326-23-8 |
|
Methyl 3,3-Dimethoxypropionate, 99%
| 7424-54-6 |
|
1-Acetamidoadamantane, 99+%
| 880-52-4 |
|
2-Nitroimidazole, 98%
| 527-73-1 |
|
Tetraphenylmethane, 97%
| 630-76-2 |
|
8-Nitroquinoline, 98%
| 607-35-2 |
|
3-Octylthiophene, 94%, remainder mainly tetradecane
| 65016-62-8 |
|
4-Nitrobenzophenone, 99+%
| 1144-74-7 |
|
9-Chloroacridine
| 1207-69-8 |
|
4-Epichlortetracycline hydrochloride 'can be used as secondary
| 101342-45-4 |
|
Sarcosine Hydrochloride, 99%
| 637-96-7 |
|
5-alpha-Cholestan-3-one, 97%
| 15600-08-5 |
|
n-Glycyl-l-isoleucine, 99%
| 19462-38-2 |
|
2,4-Dinitrophenylacetic Acid, Tech., 90%(GC)
| 643-43-6 |
|
2-Chloroethanesulfonyl Chloride, 95% (gc)
| 1622-32-8 |
|
Heptyl Isothiocyanate
| 4426-83-9 |
|
Alpha-Bromo-Meta-Tolunitrile, 95%
| 28188-41-2 |
|
Phenylpropiolic acid, 97%
| 637-44-5 |
|
2,3,5-Trimethylphenol, 98+%
| 697-82-5 |
|
2,4-Dinitrophenyl Acetate
| 4232-27-3 |
|
(1r,2r)-(+)-n,n'-dimethyl-1,2-diphenyl-1,2 -ethane diamine, 99%
| 118628-68-5 |
|
Isobutyric anhydride, 97%
| 97-72-3 |
|
Diethyl Ketomalonate, 95% (GC)
| 609-09-6 |
|
3-Aminopyrazine-2-Carboxylic Acid, 99+%
| 5424-01-1 |
|
2,3' -diethyl-9-methylthiacarbocyanine iodide
| 3065-79-0 |
|
6-Chloro-2-Pyridinol, 98%
| 16879-02-0 |
|
9-Aminofluorene hydrochloride, 99%
| 5978-75-6 |
|
1-Methoxy-3-(Trimethylsilyloxy)-1,3-Butadiene, 90%
| 59414-23-2 |
|
Aminoacetonitrile Hydrochloride, 99%
| 6011-14-9 |
|
Diphenylphosphinyl Chloride, 98%
| 1499-21-4 |
|
2-(2-Tritylaminothiazole-4-Yl)-2-Methoxyiminoacetic Acid
| 64485-90-1 |
|
Antimony (III) Sulfide, 98%
| 1345-04-6 |
|
Magnesiumhydrogenphosphate trihydrate, c.p
| 7782-75-4 |
|
1-Hydroxyethylethoxypiperazine, 95%
| 13349-82-1 |
|
4'-Chloroacetoacetanilide, 98%
| 101-92-8 |
|
Cycloheximide
| 66-81-9 |
|
??2,4??-Dibenzo-18-Crown-6, 99+%
| 14187-32-7 |
|
Cyanuric Chloride, 99% (Titr.)
| 108-77-0 |
|
Alpha-Toluenesulfonamide
| 4563-33-1 |
|
Ethyl 2-Mercaptoacetate, 99% (GC)
| 623-51-8 |
|
N-Carbethoxy-4-Tropinone, 98%
| 32499-64-2 |
|
2,3-Dimethylquinoxaline, 97%
| 2379-55-7 |
|
Potassium perchlorate
| 7778-74-7 |
|
Benzylamine
| 100-46-9 |
|
N-Omega-Acetylhistamine, 98%
| 673-49-4 |
|
|