**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 75-31-0 |Isopropylamine | ca.100 | 200-860-9 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XI F+
Risk Phrases: 12 36/37/38
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Extremely flammable. Irritating to eyes, respiratory system and
skin.Corrosive.
Potential Health Effects
Eye:
May cause 'blue haze' or 'halo vision'. Causes eye irritation and
burns. May cause tearing, conjunctivitis and corneal edema when
vapor is absorbed into the tissue of the eye. Direct contact with
liquid may cause blindness or permanent eye damage.
Skin:
Harmful if absorbed through the skin. May cause skin sensitization,
an allergic reaction, which becomes evident upon re-exposure to this
material. Causes severe skin irritation and burns.
Ingestion:
Causes gastrointestinal tract burns. May cause central nervous
system depression, characterized by excitement, followed by headache,
dizziness, drowsiness, and nausea. Advanced stages may cause
collapse, unconsciousness, coma and possible death due to respiratory
failure. May be harmful if swallowed.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by nausea, headache, dizziness, unconsciousness
and coma. Inhalation of high concentrations may cause narcotic
effects. Can produce delayed pulmonary edema. Causes respiratory
tract irritation with possible burns.
Chronic:
Prolonged or repeated skin contact may cause dermatitis.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Get medical aid immediately. Do NOT allow victim to rub or keep eyes
closed. Extensive irrigation with water is required (at least 30
minutes).
Skin:
Get medical aid immediately. Immediately flush skin with plenty of
soap and water for at least 15 minutes while removing contaminated
clothing and shoes. Discard contaminated clothing in a manner which
limits further exposure. Destroy contaminated shoes.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure to fresh air immediately. If breathing is
difficult, give oxygen. Get medical aid. Do NOT use mouth-to-mouth
resuscitation. If breathing has ceased apply artificial respiration
using oxygen and a suitable mechanical device such as a bag and a
mask.
Notes to Physician:
Treat symptomatically and supportively. Rapidly penetrates eye
tissue. Extensive flushing of the eye is recommended. Persons with
asthma, chronic respiratory disease, skin disorders, eye problems or
allergies may be at increased risk from exposure to this substance.
Antidote:
Do not apply greases or ointments.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
Containers can build up pressure if exposed to heat and/or fire. As
in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors may form an explosive mixture with air.
Vapors can travel to a source of ignition and flash back. During a
fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Use water spray to keep fire-exposed
containers cool. Water may be ineffective. Material is lighter than
water and a fire may be spread by the use of water. Flammable liquid
and vapor. Vapors may be heavier than air. They can spread along the
ground and collect in low or confined areas. May polymerize
explosively when involved in a fire. May be ignited by heat, sparks,
and flame. Will be easily ignited by heat, sparks or flame.
Extinguishing Media:
Water may be ineffective. Do NOT get water inside containers. Do NOT
use straight streams of water. Cool containers with flooding
quantities of water until well after fire is out. For large fires,
use water spray or alcohol foam. For small fires, use carbon dioxide,
dry chemical, dry sand or limestone.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Clean up spills immediately,
observing precautions in the Protective Equipment section. Remove all
sources of ignition. Use a spark-proof tool. Provide ventilation. Do
not get water inside containers. A vapor suppressing foam may be
used to reduce vapors. Water spray may reduce vapor but may not
prevent ignition in closed spaces.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Ground and
bond containers when transferring material. Do not breathe dust,
vapor, mist, or gas. Do not get in eyes, on skin, or on clothing.
Empty containers retain product residue, (liquid and/or vapor), and
can be dangerous. Keep container tightly closed. Avoid contact with
heat, sparks and flame. Do not ingest or inhale. Do not pressurize,
cut, weld, braze, solder, drill, grind, or expose empty containers
to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of
ignition. Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances. Keep
refrigerated. (Store below 4C/39F.) Store in steel containers.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use process enclosure, local exhaust ventilation, or other
engineering controls to control airborne levels below recommended
exposure limits. Use explosion-proof ventilation equipment.
Facilities storing or utilizing this material should be equipped with
an eyewash facility and a safety shower.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
A respiratory protection program that meets OSHA's 29
CFR ??1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Liquid
Appearance: colorless liquid
Odor: ammonia-like
pH: Strong Base (12.30)
Vapor Pressure: 248 mm Hg @ 20 deg C
Viscosity: Not available.
Boiling Point: 47 deg C
Freezing/Melting Point: -83 deg C
Autoignition Temperature: 402 deg C ( 755.60 deg F)
Flash Point: -35 deg C ( -31.00 deg F)
Explosion Limits, lower: 2.00 vol %
Explosion Limits, upper: 10.4 vol %
Decomposition Temperature:
Solubility in water: Miscible.
Specific Gravity/Density: 0.694
Molecular Formula: CH3CH2CH2NH2
Molecular Weight: 59.0697
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong acids, acid chlorides, acid
anhydrides, perchloryl fluoride, 1-chloro-1,3-epoxypropane,
aldehydes, epoxides (e.g. butyl glycidyl ether), halogenated agents,
mineral acids, organic acids, sodium hypochlorite, calcium
hypochlorite, copper, aluminum, zinc, galvanized surfaces, peroxides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and
gases, carbon dioxide, ammonia, nitric acid.
Hazardous Polymerization: Will not occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 75-31-0: NT8400000
LD50/LC50:
CAS# 75-31-0: Draize test, rabbit, eye: 100 uL Severe; Inhalation,
rat: LC50 = 4000 ppm/4H; Oral, mouse: LD50 = 2200 mg/kg; Oral,
rabbit: LD50 = 3200 mg/kg; Oral, rat: LD50 = 111 mg/kg; Skin,
rabbit: LD50 = 380 mg/kg.
Carcinogenicity:
Isopropylamine -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Water flea Daphnia: EC50 = 91.5-91.6 mg/L; 48 Hr; UnspecifiedBased on
the vapor pressure, isopropylamine should rapidly evaporate from dry
surfaces, especially when present in high concn such as in spill
situations. The miscibility of isopropylamine in water suggests that
adsorption and bioconcentration, in addition to volatilization, are
not important fate processes. This is supported by low estimates for
the bioconcentration factor (log BCF = 0.43) and soil adsorption
coefficient (Koc = 33).
Other
Harmful to aquatic life in very low concentrations. Waste from this
product may present long-term environmental hazards.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ISOPROPYLAMINE
Hazard Class: 3
UN Number: 1221
Packing Group: I
IMO
Shipping Name: ISOPROPYLAMINE
Hazard Class: 3
UN Number: 1221
Packing Group: I
RID/ADR
Shipping Name: ISOPROPYLAMINE
Dangerous Goods Code: 3(22A)
UN Number: 1221
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI F+
Risk Phrases:
R 12 Extremely flammable.
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 29 Do not empty into drains.
WGK (Water Danger/Protection)
CAS# 75-31-0: 2
United Kingdom Occupational Exposure Limits
Canada
CAS# 75-31-0 is listed on Canada's DSL List.
CAS# 75-31-0 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 75-31-0: OEL-AUSTRALIA:TWA 5 ppm (12 mg/m3);STEL 10 ppm (24 mg/m3
)
OEL-BELGIUM:TWA 5 ppm (12 mg/m3);STEL 10 ppm (24 mg/m3)
OEL-DENMARK:TWA 5 ppm (12 mg/m3)
OEL-FRANCE:TWA 5 ppm (12 mg/m3)
OEL-GERMANY:TWA 5 ppm (12 mg/m3)
OEL-THE NETHERLANDS:TWA 5 ppm (12 mg/m3)
OEL-THE PHILIPPINES:TWA 5 ppm (12 mg/m3)
OEL-RUSSIA:STEL 1 mg/m3
OEL-SWITZERLAND:TWA 5 ppm (12 mg/m3);STEL 10 ppm (24 mg/m3)
OEL-TURKEY:TWA 5 ppm (12 mg/m3)
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 75-31-0 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 6/17/1999 Revision #1 Date: 8/02/2000
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|