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MSDS  : Silicic acid (H2SiO3), disodium salt
CAS  : 6834-92-0
SYNONYMS  : * B-W * Crystamet * Disodium metasilicate * Disodium monosilicate * Metso 20 * Metso beads 2048 * Metso beads, drymet * Metso pentabead 20 * Orthosil * Sodium metasilicate * Sodium metasilicate, anhydrous * Sodium silicate * Water glass
*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER : VV9275000
CHEMICAL NAME : Silicic acid (H2SiO3), disodium salt
CAS REGISTRY NUMBER : 6834-92-0
LAST UPDATED : 199710
DATA ITEMS CITED : 18
MOLECULAR FORMULA : O3-Si.2Na
MOLECULAR WEIGHT : 122.07
WISWESSER LINE NOTATION : NA2 SI-O3
COMPOUND DESCRIPTOR : Reproductive Effector
Primary Irritant
SYNONYMS/TRADE NAMES :
* B-W
* Crystamet
* Disodium metasilicate
* Disodium monosilicate
* Metso 20
* Metso beads 2048
* Metso beads, drymet
* Metso pentabead 20
* Orthosil
* Sodium metasilicate
* Sodium metasilicate, anhydrous
* Sodium silicate
* Water glass

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Human
DOSE/DURATION : 250 mg/24H
REACTION SEVERITY : Severe
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
31,481,1975

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 250 mg/24H
REACTION SEVERITY : Severe
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
31,481,1975

TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 250 mg/24H
REACTION SEVERITY : Moderate
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year:
31,481,1975

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1153 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
Gastrointestinal - ulceration or bleeding from duodenum
Gastrointestinal - ulceration or bleeding from small intestine
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year:
31(Suppl),44,1986

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 770 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
Gastrointestinal - ulceration or bleeding from duodenum
Gastrointestinal - ulceration or bleeding from small intestine
REFERENCE :
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year:
31(Suppl),44,1986

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - dog
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes
Gastrointestinal - other changes
Kidney, Ureter, Bladder - other changes
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 14,78,1976

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Mammal - pig
DOSE/DURATION : 250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For
publisher information, see FCTOD7. Volume(issue)/page/year: 14,78,1976

TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N.
Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year:
111,1925,1938

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 15 gm/kg
SEX/DURATION : male 14 week(s) pre-mating
female 14 week(s) pre-mating - 3 week(s) post-birth
TOXIC EFFECTS :
Reproductive - Effects on Newborn - stillbirth
Reproductive - Effects on Newborn - live birth index (measured after birth)
Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
alive at weaning per # alive at day 4)
REFERENCE :
JANSAG Journal of Animal Science. (American Soc. of Animal Science, 309 W.
Clark St., Champaign, IL 61820) V.1- 1942- Volume(issue)/page/year:
36,271,1973

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 9766 ug/kg
SEX/DURATION : male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 7,21,1964

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intratesticular
SPECIES OBSERVED : Rodent - rat
DOSE : 9766 ug/kg
SEX/DURATION : male 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 7,21,1964

*** REVIEWS ***

TOXICOLOGY REVIEW
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB-287-766

*** U.S. STANDARDS AND REGULATIONS ***

EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - 80079
No. of Facilities: 97326 (estimated)
No. of Industries: 300
No. of Occupations: 154
No. of Employees: 838120 (estimated)

NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - 80079
No. of Facilities: 59514 (estimated)
No. of Industries: 281
No. of Occupations: 164
No. of Employees: 971688 (estimated)
No. of Female Employees: 275947 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998


*** END OF RECORD ***
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Silicate, soapstoneSUBSTANCE DEFINITION :Containing less than 1% crystalline silicaREFERENCE :FEREAC Federal Register. (U.S. Government Printing Office, Supt. ofDocuments, Washington, DC 20402) V.1- 1936- 65997-15-1
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Silicic acid, beryllium salt 15191-85-2
Silicic acid, beryllium zinc salt 39413-47-3
SF-1508 56378-68-8
Silicic acid, calcium salt 1344-95-2
Silicic acid (H2SiO3), calcium salt (11) 10101-39-0
Silicic acid, 2-chloroethyl ester 10101-39-0
Silicic acid (H2SiO3), disodium salt 6834-92-0
Silicic acid, 2-ethylbutyl ester 68037-57-0
Silicic acid, methyl ester 12002-26-5
Silicic acid, tetra(2-ethylbutyl) ester 78-13-7
Silicic acid, tetraethyl ester 78-10-4
Silicic acid, tetra(2-fluoroethyl) ester 650-00-0
Silicic acid, tetrakis(2-chloroethyl) ester 18290-84-1
SF-1739 61991-01-3
Silicic acid (H2SiO4), tetrakis(1-methylpropyl) ester 5089-76-9
Silicic acid, tetramethyl ester 681-84-5
Silicon 7440-21-3
Silicon(1+),(1-(bis(2-hydroxyethyl)amino)-2-propanolato(3-)-N,O,O',O") (ethylmethylsulfonium eta-methylide)-, iodide,(TB-5-34)- 67349-10-4
Silicon carbide 409-21-2
Silicon chloride 10026-04-7
Silicon chrome 11133-78-1
Silicon(1+), (diethylsulfoniumeta-methylide)((1,1',1"-nitrilotris(2-propanolato))(3-)- N,O,O',O")-, bromide, (TB-5-23) 67366-36-3
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SF 3024-B20-KOSUBSTANCE DEFINITION :Phenol resin which is mixture of oligomersREFERENCE :GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene andOccupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)V.1-36, 1957-1992. For publisher information, see MTPEEIVolume(issue)/page/year: 28(7),53,1984 67349-11-5
Silicon,(3,3,4,4,5,5,6,6,7,7,8,8-dodecafluoro-1-iodooctyl)((2,2'2,''-nitrilotris(e thanolato))(3-)-N,O,O',O'')-,(TB-5-23)- 135798-16-2
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Silicon,(3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-hexadecafluoro-1-iododecyl)((2,2',2''-n itrilotris(ethanolato))(3-)-N,O,O',O'')-, (TB-5-23)- 135798-17-3
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Silicone 7158 112341-57-8
Silicone antifoam sag-47 112341-57-8
SF-1540 A 71329-58-3
Silicone antifoam sag-100 71329-58-3
Silicone C-25 71329-58-3
Silicone fluid L-43 71329-58-3
Silicone L-31 71329-58-3
Silicone L-42 (oil) 71329-58-3
Silicone L-45 63148-62-9
Silicone L-75 63148-53-8
Silicone L-76 63148-53-8
Silicone L-77 63148-53-8

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