*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : CD2995850
CHEMICAL NAME : Antipyrine, 4-(methylamino)-
CAS REGISTRY NUMBER : 519-98-2
BEILSTEIN REFERENCE NO. : 0195234
REFERENCE : 5-25-14-00116 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 5
MOLECULAR FORMULA : C12-H15-N3-O
MOLECULAR WEIGHT : 217.30
COMPOUND DESCRIPTOR : Drug
SYNONYMS/TRADE NAMES :
* Methylaminoantipyrine
* N-Methylaminoantipyrine
* 4-(Methylamino)antipyrine
* Methylaminophenazone
* N-Methylaminophenazone
* 4-Methylaminophenazone
* Monomethylaminoantipyrine
* 4-Monomethylaminoantipyrine
* 4-Monomethylaminophenazone
* N.A.P.
* Noramidopyrine
* Noraminopyrine
* 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1288 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 30,599,1967
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 7 gm/kg
TOXIC EFFECTS :
Behavioral - analgesia
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil,
France) V.1- 1943- Volume(issue)/page/year: 35,489,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1255 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon
Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year:
71,609,1975
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 400 mg/kg
TOXIC EFFECTS :
Behavioral - analgesia
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
(Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
V.9- 1974- Volume(issue)/page/year: 21,277,1986
** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1691 mg/kg/3D-I
TOXIC EFFECTS :
Liver - changes in liver weight
Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc.,
c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto
606, Japan) V.1- 1951- Volume(issue)/page/year: 43,335,1987
*** END OF RECORD ***
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| ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
| | NAME | CAS |
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Antineoplaston A5
| 142191-84-2 |
|
Antineoplaston AS2-1
| 104624-98-8 |
|
Antineoplaston AS2-5
| 104771-87-1 |
|
Antibiotic SF 1306A
| 52934-70-0 |
|
Antiogoside
| 3981-17-7 |
|
Antioside
| 3981-16-6 |
|
Antioxidant G-15
| 3981-16-6 |
|
Antioxidant G-16
| 61373-87-3 |
|
Antioxidant KSM
| 52622-55-6 |
|
Antioxidant TSP
| 12789-66-1 |
|
Antiphlei factor-ISUBSTANCE DEFINITION :Isolated from Streptomyces aureusREFERENCE :85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., BocaRaton, FL, CRC Press, 1980- Volume(issue)/page/year: 1,407,1980
| 12789-66-1 |
|
Antipyrine
| 60-80-0 |
|
Antipyrine, 4-(beta-acetylstyryl)-
| 24428-81-7 |
|
Antipyrine, 4-allyl-
| 24428-81-7 |
|
Antibiotic SF-1670-A
| 60440-43-9 |
|
Antipyrine, 4-amino-
| 83-07-8 |
|
Antipyrine, 4-(2-(p-aminobenzoyl)ethyl)-
| 24428-98-6 |
|
Antipyrine, 4-amino-, and sodium nitrite
| 24428-98-6 |
|
Antipyrine, 4-(2-(p-anisoyl)vinyl)-
| 24428-77-1 |
|
Antipyrine, 4,4'-azodi-
| 102585-65-9 |
|
Antipyrine, 4-(2-benzoylpropenyl)-
| 24428-80-6 |
|
Antipyrine, 4-(2-benzoylvinyl)-
| 15183-03-6 |
|
Antipyrine, 4-butyl-
| 101496-03-1 |
|
Antipyrine, 4-sec-butyl-
| 96974-48-0 |
|
Antipyrine, compd. with chloral hydrate (12)
| 480-30-8 |
|
Antibiotic SF 2107 A(sub 1)
| 81030-78-6 |
|
Antipyrine, 4-(2-(p-chlorobenzoyl)vinyl)-
| 24429-12-7 |
|
Antipyrine, 4-((p-chlorophenacylidene)amino)-
| 24377-61-5 |
|
Antipyrine, 4-(2-(diethylamino)ethyl)-
| 24377-61-5 |
|
Antipyrine,4-((3,4-dimethoxy-2-(1-pyrrolidinylcarbonyl)benzylidene)amino)-
| 66913-52-8 |
|
Antipyrine, 4-(dimethylamino)-
| 58-15-1 |
|
Antipyrine, 4-(dimethylamino)- mixed with sodiumnitrite (1:1)
| 58-15-1 |
|
Antipyrine, 4-(dimethylamino)-, sodium salt
| 6062-19-7 |
|
Antipyrine, 4-(2,6-dimethylpiperidinothiocarbamoyl)-
| 73791-34-1 |
|
Antipyrine, 4-ethyl-
| 73791-34-1 |
|
Antipyrine, 4-(ethylamino)-
| 15166-10-6 |
|
Antibiotic SF 1306B
| 52934-72-2 |
|
Antipyrine, 4-(2-(p-hydroxybenzoyl)propenyl)-,hydrate
| 26405-20-9 |
|
Antipyrine, 4-isobutyl-
| 26405-20-9 |
|
Antipyrine, 4-isopentyl-
| 26405-20-9 |
|
Antipyrine, 4-isopropyl-
| 479-92-5 |
|
Antipyrine, 4-(isopropylamino)-
| 3615-24-5 |
|
Antipyrine, 4-((m-methoxybenzylidene)amino)-
| 70318-54-6 |
|
Antipyrine, 4-((p-methoxybenzylidene)amino)-
| 32061-14-6 |
|
Antipyrine, 4-((p-methoxyphenacylidene)amino)-
| 24428-97-5 |
|
Antipyrine, 4-(methylamino)-
| 519-98-2 |
|
Antipyrine, 4-((p-methylphenacylidene)amino)-
| 24428-96-4 |
|
Antibiotic SF 1771B
| 63798-93-6 |
|
Antipyrine,4-(4-(3-methyl-2-phenylmorpholino)methyl)-, gentisate
| 63798-93-6 |
|
Antipyrine,4-(4-(3-methyl-2-phenylmorpholino)methyl)-,hydrochloride
| 50321-35-2 |
|
|